[PDF] Top 20 Oligomeric structure of gp41, the transmembrane protein of human immunodeficiency virus type 1.
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Oligomeric structure of gp41, the transmembrane protein of human immunodeficiency virus type 1.
... Commercially prepared test strips containing solubilized HTLV-Illb lysates Organon Teknika were treated by standard protocols with the following antibodies: lane 1, human serum from a pa[r] ... See full document
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The Cytoplasmic Domain of Human Immunodeficiency Virus Type 1 Transmembrane Protein gp41 Harbors Lipid Raft Association Determinants
... pro- virus were treated with different concentrations of  -MCD, which depletes cholesterol from the cell surface, at 37°C for 30 min ...with 1% Triton X-100 in PBS on ice and subjected to sucrose density ... See full document
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Peptides Corresponding to the Heptad Repeat Motifs in the Transmembrane Protein (gp41) of Human Immunodeficiency Virus Type 1 Elicit Antibodies to Receptor-Activated Conformations of the Envelope Glycoprotein
... the human immunode- ficiency virus type 1 (HIV-1) mediates virus entry by fusing viral and cellular membranes, resulting in delivery of the viral nucleocapsid to the cell ...the ... See full document
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Cellular Membrane-Binding Ability of the C-Terminal Cytoplasmic Domain of Human Immunodeficiency Virus Type 1 Envelope Transmembrane Protein gp41
... in virus-infected or Env-expressing ...simplex virus (HSV) Env glycoprotein gD-1 translocates across microsomal membranes ...the gp41 cytoplasmic tail has a close asso- ciation with cellular ... See full document
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Biophysical characterization of recombinant proteins expressing the leucine zipper-like domain of the human immunodeficiency virus type 1 transmembrane protein gp41.
... the gp41 zipper motif are critical for virus entry but not for Env assembly into oligomeric complexes (10, 11, 18, 51, ...the gp41 ectodomain is sufficient to direct the stable oligomeriza- ... See full document
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Epitope mapping of two immunodominant domains of gp41, the transmembrane protein of human immunodeficiency virus type 1, using ten human monoclonal antibodies.
... GORNY,1 THOMAS PALKER,2 SYLWIA KARWOWSKA,1 AND SUSAN ZOLLA-PAZNERl 3* Received 13 March 1991/Accepted 30 May 1991 Immunogenic regions of the gp4l transmembrane protein of human immunodef[r] ... See full document
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Structure-Function Studies of the Self-Assembly Domain of the Human Immunodeficiency Virus Type 1 Transmembrane Protein gp41
... each other, respectively (see Fig. 4C in reference 19). Q563 side chains also interact with hydrophobic residues L565, I642, and I646 (Fig. 5B). Smaller substitutions with alanine and glycine in position 563 probably do ... See full document
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Functional role of the zipper motif region of human immunodeficiency virus type 1 transmembrane protein gp41.
... 2002 Downloaded from http://jvi.asm.org/ on November 9, 2019 by guest To study the functional role of the zipper motif region, located in the N-terminal region of the envelope transmembr[r] ... See full document
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Mutational Analysis of Residues in the Coiled-Coil Domain of Human Immunodeficiency Virus Type 1 Transmembrane Protein gp41
... In this report, we describe the results of studies involving mutations in the coiled-coil domain (residues 553 to 595, here- after referred to as the heptad repeat) near the fusion peptide of gp41 that potentially ... See full document
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Immunogenicity and Protective Efficacy of Oligomeric Human Immunodeficiency Virus Type 1 gp140
... the human immunodeficiency virus type 1 (HIV-1) envelope (Env) glycopro- tein is ...Env protein, gp140, with a stable oligomeric structure composed of ... See full document
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Identification of the LWYIK Motif Located in the Human Immunodeficiency Virus Type 1 Transmembrane gp41 Protein as a Distinct Determinant for Viral Infection
... the gp41 transmembrane protein of human immunodeficiency virus type 1 has been proposed as being important for the surface envelope (Env) glycoprotein’s association ... See full document
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Determinants of human immunodeficiency virus type 1 envelope glycoprotein oligomeric structure.
... influenza virus hemagglutinin (7, 28, 47, 68) as well as HIV-1 gp160 and gp41 (13, 50, 51) have been de- tected by using polyclonal antibodies and ...of oligomeric structure resulting ... See full document
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Oligomeric Structure of the Human Immunodeficiency Virus Type 1 Envelope Protein on the Virion Surface
... envelope protein (Env) of human immunodeficiency virus type 1 (HIV-1) mediates functions that are critical to the viral life cycle, including viral attachment to target ... See full document
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Mutation-Directed Chemical Cross-Linking of Human Immunodeficiency Virus Type 1 gp41 Oligomers
... mutant gp41 cross-linking pattern, we observed that gp41 N termini are ...the transmembrane sequence, was readily cross-linked to Lys-678 on other monomers within the oligomeric ...surface ... See full document
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A Mutation in the Human Immunodeficiency Virus Type 1 Gag Protein Destabilizes the Interaction of the Envelope Protein Subunits gp120 and gp41
... HIV-1 virus-cell fusion ...fusion-competent virus and functional receptors on cells ...on virus-cell interactions that result in fusion. Inoculation with wild type HIV-1 reporter ... See full document
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Evidence for a Stable Interaction of gp41 with Pr55Gag in Immature Human Immunodeficiency Virus Type 1 Particles
... in 1⫻ sodium dodecyl sulfate (SDS) sample buffer for subsequent immunoblot ...Trono), human monoclonal antiserum against gp41 (C2F5) and gp120 (C2G12) (obtained from the NIH AIDS Re- search and ... See full document
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Role of a Putative gp41 Dimerization Domain in Human Immunodeficiency Virus Type 1 Membrane Fusion
... of human immunodeficiency virus type 1 (HIV-1) into a target cell entails a series of conforma- tional changes in the gp41 transmembrane glycoprotein that mediates ... See full document
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Structure-function studies of the human immunodeficiency virus type 1 matrix protein, p17.
... A particularly interesting mutant was the R39E,R43E dou- ble substitution. These arginine residues lie on the outside of helix A (Fig. 7B) and may well be part of the basic region that is involved in localization to the ... See full document
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Determinants of Tetherin Antagonism in the Transmembrane Domain of the Human Immunodeficiency Virus Type 1 Vpu Protein
... some extent here too, although these proteins now do not target CD4. HIV-1 group O Vpu proteins, by contrast, are devoid of tetherin antagonistic activity, while remaining capa- ble of targeting CD4 (53). We note ... See full document
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Effect of Mutations in the Human Immunodeficiency Virus Type 1 Protease on Cleavage of the gp41 Cytoplasmic Tail
... R236L gp41, we concentrated the virions after transfecting HeLa or 293T cells and purified them by high-performance liquid chromatography (HPLC) as described previously (9, ...28). Protein elution profiles ... See full document
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