[PDF] Top 20 Is there an optimal management for localized prostate cancer?

... those prostate cancers that develop more aggressive features during a period of surveillance and while the CaP is still amenable to definitive therapy such as surgery or ... See full document

... The optimal strategy for managing localized prostate cancer has not been established and currently includes a number of potential options: active surveillance, radical prostatec- tomy, ... See full document

... lower PSA levels (<10 ng/ml after RT; <5 ng/ml after RP) and longer PSAdt (>10 months; Fig. 1). Guidance related to administration of ADT, either intermittent or continuous, is limited in guidelines and ... See full document

... in localized prostate cancer but it leads to an increase in late toxicity of normal tissues so it becomes essential the implementation of all the principals in order to mini- mize the effects side, ... See full document

... Patients often choose brachytherapy because it is re- puted to be less damaging to erectile function. In this study we observed that 36 months after implantation, 73% of men with a IIEF score more than 12 before PB had a ... See full document

... of management to radical treatment might have been undertaken for reasons other than disease ...of management in the ProtecT trial were similar to those in other active surveillance ... See full document

... ≤6 prostate cancer rarely experience metastatic progression on watchful waiting or observation and therefore the members of the Working Group and Expert Panel feel that the results from these trials give ... See full document

... The LSPR sensor were incubated in different concentrations of standard total PSA solution ranging from 1 ng/ml to 50 ng/ml under optimal conditions, and LSPR peak were obtained with peak shifts recorded. Mean ... See full document

... Without definitive clinical guidelines and strong evidence to support one treatment over another, most professional organizations encourage a shared decision-making approach in which a patient and his health care ... See full document

... for localized prostate ...for prostate cancer that recurs after radiation ...the management of recurrent prostate cancer [18, ...in prostate cancer that is ... See full document

... conservative management (CM) for patients with localized PCa with a life-expectancy ≤10 years ...for localized PCa (CM, PADT, radical prostatectomy-RP, radiation therapy-RT) in elderly patients, as ... See full document

... Despite strong generalizability from the inclusion of phys- icians from many countries and practice environments, this study has limitations. First, as the organizations who circu- lated the survey invitation would not ... See full document

... castration-resistant prostate cancer (nmCRPC), metastatic castration-sensitive prostate cancer (mCSPC), metastatic castration-resistant prostate cancer (mCRPC), oligometastatic ... See full document

... an optimal HbA 1c threshold to predict diabetes complications and 2) to assess how well the recommended ...consistent optimal HbA 1c threshold for diabetes complications cannot be derived, and the ... See full document

... ported that the degree of post biopsy hemorrhage detected by MR image has a significant association with operative outcome such as operative time, estimated blood loss, and return of erectile function in patients who ... See full document

... aggressive cancer. Based on their Gleason scores, the prostate cancer cases were classified into mildly aggressive (5-6), moderately aggressive (7) and highly aggressive ...the prostate ... See full document

... of prostate cancer ...for prostate cancer patients, other elderly pa- tients without prostate cancer could be concerned by some of the issues mentioned in this ... See full document

... Microarrays analysis has been used to characterize the molecular profiles of breast cancer [72–74]. Important advances are being made in the use of genetic analysis to determine the risk of recurrence and to ... See full document

... qRT-PCR and in silico expression analyses confirm recent reports from smaller series about EEF1A2 overexpression in localized PCa. Furthermore this is the first study describing EEF1A2 expression to be stage- and ... See full document

... cludes Cancer of the Prostate Strategic Urologic Re- search Endeavor (CaPSURE) data was produced to pre- dict continence, erection status with physical and mental outcomes in the first year after RP ... See full document