[PDF] Top 20 Original Article Differential expression of PI3K isoforms and correlation with clinicopathological factors in patients with gastric cancer

... 153 patients died, 20 (13%) devel- oped recurrent disease and 10 (7%) were lost to ...p110γ expression was associ- ated with longer RFS, but this finding was not significant ...(P=0.053). Expression ... See full document

... man isoforms; HSP90α, HSP90β, glucose related protein 94 (GRP94) and tumor necrosis factor (TNF) receptor- associated protein 1 ...the differential expression of these HSP90 isoforms in ... See full document

... GC patients, was unable to elucidate a significant correlation between p110δ expres- sion and clinicopathological factors or patient survival, even though GCs with advanced stage or nodal ... See full document

... CDC20 expression and survival duration using a Kaplan-Meier analysis with a log-rank ...CDC20 expression was significantly associated to the survival of GC ...of patients with high CDC20 expres- sion ... See full document

... human isoforms; HSP90α, HSP90β, glucose related protein 94 (GRP94), and tumor necrosis factor (TNF) receptor-associated protein 1 ...the differential expression of these HSP90 isoforms in ... See full document

... breast cancer via immunohisto- chemical detection of the tumor cell-expressed molecules of ER, PR and Her2, which is similar to the molecular typing by gene sequencing that has been proved to be a vital prognostic ... See full document

... of gastric cancer samples with lymph node metastasis or ...protein expression was down-regulated by RNA interference, and a series of cytobiology functions were examined in ...protein ... See full document

... the correlation between miR-421 level and disease indexes to screen out those parameters with statistical signifi- ...of patients was analyzed by Kaplan-Meier survival curve, along with the ... See full document

... with clinicopathological features of GC ...important factors correlated with unfavorable outcomes of GC patients, may also show a possibility of Dicer as an indicator for GC ...aberrant ... See full document

... Originated from neural ectoderm, glioma accounts for about 40%-60% of brain cancers. Glioma, characterized by strong invasion capa- bility, high recurrence rate, poor prognosis, and high mortality, seriously affects ... See full document

... as gastric cancer [33], colon cancer [34], breast cancer [35] and esophageal carcinoma ...reduced expression of E-cadherin is common- ly caused by several molecular mechanisms ... See full document

... in gastric cancer ...and clinicopathological features along with pa- tients’ survival ...GC patients who received radical gastrec- tomy in Fudan University Shanghai Cancer ...Center. ... See full document

... in patients with advanced gas- tric carcinomas, Shh protein has an effect to promote carcinogenesis, progression, and in- crease cancer ...human gastric cancer [45, 46]. Second, chronic ... See full document

... in cancer initiation and ...with clinicopathological characteristics of gastric cancer in patients have been ...108 patients, and were subsequently categorized into low and high ... See full document

... The PI3K/AKT pathway performs critical func- tions in the regulation of cell growth, prolifera- tion, metabolism, survival and motility [3-5], and it is known that aberrant activation of this intracellular ... See full document

... including gastric cancer, ovarian cancer, lung cancer, pancreatic cancer and liver ...(Cox-2) expression and increased epidermal growth factor receptor (EGFR) signal transduction ... See full document

... gene expression profiling can simul- taneously assess the expression of thousands of genes, which was regarded as the powerful method for clarifying the biological characteris- tics of ...gene ... See full document

... positive gastric cancer, 25 cases were hepatoid type, which was the most common type and is consistent with the findings of Motoyama et al ...the correlation between AFP immunohistochemical staining ... See full document

... induce cancer formation ...of gastric cancer requires further ...of gastric cancer. The vari- ant genotype AG+GG in the gastric cancer group showed no significant ... See full document

... for gastric cancer. Our study has demonstrated a correlation between Bcl-2 expression and chemosensitivity in gastric can- cer to five widely used anticancer drugs; how- ever, further ... See full document