[PDF] Top 20 Original Article Effect of Torin 1 on suppressing inflammation in mice with dextran sodium sulfate-induced colitis
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Original Article Effect of Torin 1 on suppressing inflammation in mice with dextran sodium sulfate-induced colitis
... ulcerative colitis (UC) and Crohn’s disease (CD), still remains ...of Torin 1, an inhibitor of mTOR, in Dextran sulfate sodium (DSS)-induced experimental ...that ... See full document
9
Hyperoside attenuates dextran sulfate sodium-induced colitis in mice possibly via activation of the Nrf2 signalling pathway
... local inflammation and immune dysfunction, changes that trigger a positive feedback loop leading to the development of and increases in inflammation, resulting in intestinal mucosal damage ...experimental ... See full document
10
LL202 protects against dextran sulfate sodium-induced experimental colitis in mice by inhibiting MAPK/AP-1 signaling
... in inflammation along with its mechanism has not been ...anti-inflammatory effect of LL202 on intestinal inflammation by establishing dextran sulfate sodium (DSS)-induced ... See full document
14
Original Article Immuno-modulatory mechanism of T cell immunoglobulin mucin-1 antibody in experimental colitis induced by dextran sulfate sodium
... local inflammation is charac- terized by hyperemia, edema, hemorrhage and infiltration of inflammatory ...DSS colitis, the num- bers of pre-B cells in bone marrow and pre-T cells in thymus decreased, while ... See full document
10
The impact of JNK inhibitor D-JNKI-1 in a murine model of chronic colitis induced by dextran sulfate sodium
... chronic colitis. Histological analysis of the colon in the DSS-treated mice showed mod- erate inflammation, with slight immune cell infiltration and ulcerative tissue ...histological ... See full document
11
Original Article Chebulagic acid reduces inflammation and regulates enteric glial cells in mouse models of dextran sulfate sodium-induced colitis
... DSS-induced colitis, but the mechanisms responsible for this impaired glial function are not clearly under- ...mucosal inflammation [5, 6, 16, ...in mice with DSS- induced ... See full document
7
Umbilical cord mesenchymal stem cells modulate dextran sulfate sodium induced acute colitis in immunodeficient mice
... induce inflammation [6-10]. Inflammation can be induced directly by UPR pathways in stressed cells, or indirectly through interaction with immune cells re- cruited by inflammatory cytokines released ... See full document
14
THE EFFECT OF MAHKOTA DEWA (PHALERIA MACROCARPA) (SCHEFF.) FRUIT PERICARP EXTRACT ON COX-2 and β-CATENIN EXPRESSION IN MICE COLON INDUCED BY DEXTRAN SODIUM SULFATE
... anti-inflammatory effect of mahkota dewa (Phaleria macrocarpa) fruit pericarp extract on COX-2 and β-catenin expression in mice colon induced by dextran sodium sulphate ... See full document
7
Original Article BTLA associates with increased Foxp3 expression in CD4 T cells in dextran sulfate sodium-induced colitis
... Inflammatory bowel diseases (IBD), including ulcerative colitis (UC) and Crohn’s disease (CD), are chronic gastrointestinal disorders charac- terized by chronic intestinal inflammation. Although it is ... See full document
12
EVALUATION OF ETHANOLIC EXTRACT OF HEMIDESMUS INDICUS IN COMBINATION WITH OCIMUM BASILICUM FOR DEXTRAN SULFATE SODIUM INDUCED COLITIS IN MICE
... Ulcerative colitis and Crohn’s disease. Our study shows mostly the Dextran Sodium Sulphate induced colitis ...Ulcerative colitis is the long-lasting inflammation that is ... See full document
5
Original Article The effects of Qing Hua Chang Yin on the epithelial tight junctions of mice with inflammatory bowel disease
... profound colitis and the DSS treated mice exhibited all the manifestations characteristic of IBD including blood in the stool, diarrhea, weight loss, and the pathological features of gastrointestinal ... See full document
10
Dendrophthoe pentandra (L ) Miq extract effectively inhibits inflammation, proliferation and induces p53 expression on colitis associated colon cancer
... The cell proliferation patterns in the colon tissue were assessed by using BrdU immunohistochemistry. We used 4 μm thick paraffin-embedded sections from the colons of the mice in all groups then visualized by BrdU ... See full document
8
Atopic Dermatitis Deteriorates Dextran Sodium Sulfate Induced Ulcerative Colitis via Thymic Stromal Lymphopoietin in Mice
... model mice suggest that the pathway of TSLP/DC/Th2 cells becomes activated by DSS, sub- sequently deteriorating ulcerative ...been induced by activated DCs, with activated Th17 cells increasing the ... See full document
15
Fermented herbal formula KIOM MA 128 protects against acute colitis induced by dextran sodium sulfate in mice
... to mice or other animals for several days has direct toxic effects on epithelial cells in the intestinal crypts and on the integ- rity of the barrier, recapitulating the major symptoms of acute and chronic ... See full document
7
Absence of bacterially induced RELMβ reduces injury in the dextran sodium sulfate model of colitis
... RELMβ induced a significant, time-dependent influx of neutrophils (Fig- ure ...in mice treated with vehicle control (data not ...also induced an increase in the number of infiltrating neutrophils ... See full document
11
Effect of Pentoxifylline on Experimental-dextran Sulphate Sodium-induced Colitis in Rats
... the colitis rats was on going with other ...of inflammation (clinical activity, macroscopic and microscopic damage scores), we can say TNF-α might be one of the key inflammatory mediators in the ... See full document
21
Effect of exercise on chemically-induced colitis in adiponectin deficient mice
... ulcerative colitis by modulating the se- cretion of local cytokine and epithelial cell proliferation in acute DSS-induced ...APNKO mice or whether it will moderate inflammation and symptoms in ... See full document
12
Regulatory effect of Garidisan on dysbiosis of the gut microbiota in the mouse model of ulcerative colitis induced by dextran sulfate sodium
... Because pathogenesis of UC has not been fully deter- mined, conventional treatment methods for this disease currently include amino salicylic acid, hormones, im- munosuppressive agents, biological agents, andtraditional ... See full document
11
Genetic deletion of IL-25 (IL-17E) confers resistance to dextran sulfate sodium-induced colitis in mice
... [13]. Mice with IL-25 deficiency (IL-25 −/− ) develop severe intestinal in- flammation during nematode infection implicating a pivotal role of IL-25 in gut mucosal homeostasis ...aggravates colitis in ... See full document
10
Expression of Blimp-1 in Dendritic Cells Modulates the Innate Inflammatory Response in Dextran Sodium Sulfate-Induced Colitis
... during inflammation (30). There is a report of increased expression of MMP-1 and MMP-2 in biopsies of pa- tients with ulcerative colitis ...cko mice compared with macrophages from WT ... See full document
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