[PDF] Top 20 Original Article Not all mutations of KRAS predict poor prognosis in patients with colorectal cancer
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Original Article Not all mutations of KRAS predict poor prognosis in patients with colorectal cancer
... of patients with normal levels. In our current study, patients with mucinous adenocarcinoma had the highest KRAS muta- tion rate among the different histologic ...addition, patients with ... See full document
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Original Article Intratumoral heterogeneity of KRAS mutations in patients with colorectal cancer and metastatic livers in southwest China
... of KRAS mutations, our study demonstrated that the frequency of KRAS mutations frequency in exon 2 was ...CRC patients from Southwest China with resectable tumors, which usually ... See full document
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Original Article CD103 expression in normal epithelium is associated with poor prognosis of colorectal cancer patients within defined subgroups
... 239 patients treated for CRC bet- ween January 2009 and December 2012 in the Colorectal Surgery Department, the Sixth Affi- liated Hospital of Sun Yat-sen University was included in this ...study. ... See full document
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Original Article Short fragment approach for genotyping KRAS and BRAF genes in Tunisian patients with colorectal cancer
... [8] Davies H, Bignell GR, Cox C, Stephens P, Ed- kins S, Clegg S, Teague J, Woffendin H, Garnett MJ, Bottomley W, Davis N, Dicks E, Ewing R, Floyd Y, Gray K, Hall S, Hawes R, Hughes J, Kos- midou V, Menzies A, Mould C, ... See full document
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Original Article Prognosis and clinical characteristics of colorectal cancer patients with KRAS gene mutation: a 5-year follow-up study
... of KRAS gene mutation and surgery for clinical characteristics and progno- sis in patients with colorectal cancer under a 5-year follow-up, clinical data of 277 patients with ... See full document
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Original Article High expression of AMPD2 and obesity are associated with poor prognosis in colorectal cancer
... the prognosis by logistic regression model results resulted in an area under the curve of ...rectal cancer were signifi- cantly upregulated in tumor tissue compare with normal tissue (Figure ...in ... See full document
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Original Article High expression of Flotillin-2 is associated with poor prognosis in Chinese patients with colorectal cancer
... pathways in human cells. Lots of studies show- ed that Flot-2 have various functions. For instance, it regulated neuronal differentiation and endocytosis, cell proliferation and invasion [6-8]. Recently, accumulating ... See full document
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Original Article Upregulated serum miR-675 predicts poor prognosis for colorectal cancer
... tives. All CRC patients were pathologically confirmed. CRC patients who received anti- cancer intervention including immunotherapy, chemothera- py or radiotherapy before sur- gical treatment ... See full document
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Original Article Downregulation of serum miR-140-5p predicts poor prognosis of patients with colorectal cancer
... Our results showed that the expression level of serum miR-140-5p was significantly down- regulated in patients with adenomas or CRC and it could discriminate CRC from adenomas as well as healthy controls with high ... See full document
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Original Article Expression of CYP1B1 and B7-H3 significantly correlates with poor prognosis in colorectal cancer patients
... Statistically significant differences between groups were determined by Student’s t test. The results are expressed as the mean ± SD. The most appropriate cutoff value for CYP1B1 and B7-H3 score was obtained by ... See full document
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Original Article Low expression of the ubiquitin ligase FBXW7 correlates with poor prognosis of patients with colorectal cancer
... In the end of study, we assessed the prognos- tic value of FBXW7 expression for CRC pati- ents’ prognosis. Our results suggested low ex- pression levels of FBXW7 were tightly correlat- ed to the worse overall and ... See full document
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Original Article Overexpression of SOX9 and DNMT1 predicts poor prognosis and chemoresistance of colorectal cancer
... Colorectal cancer has been the third most com- mon cancer and the fourth cause of cancer- related death worldwide ...The prognosis of patients with colorectal ... See full document
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Original Article High expression of lncRNA MALAT1 suggests a biomarker of poor prognosis in colorectal cancer
... bladder cancer patients who developed metastases as compared to those without metastases [32], and further analysis of the underlying mechanism showed that MALAT1 was critical for promoting epithelial- ... See full document
8
Original Article High infiltration of CD68-tumor associated macrophages, predict poor prognosis in Kazakh esophageal cancer patients
... the Patients (70 males and 30 females) was ...III-IV. All cases were confirmed and diagnosed as squamous cell carcinoma by postoperative pathological exam- ...the patients had received any ... See full document
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Original Article Decreased expression of microRNA-192 correlates with tumor progression and poor prognosis in patients with colorectal cancer
... to predict tumor progres- sion and clinical outcome in our ...in cancer tissues, adjacent-tumor tis- sues from CRC patients, and normal tissues from healthy ...in cancer tis- sues compared ... See full document
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KRAS mutations in tumor tissue and plasma by different assays predict survival of patients with metastatic colorectal cancer
... of KRAS mutations in mCRC remains ...that KRAS mutations are significantly associated with OS, but no separate ana- lysis for studies in metastatic disease was ...at KRAS status in ... See full document
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Original Article Increased expression of Prothymosin-α, independently or combined with TP53, correlates with poor prognosis in colorectal cancer
... Colorectal cancer (CRC) is the third most com- mon cancer and the third leading cause of can- cer death both in men and women worldwide ...[1]. Colorectal adenocarcinoma is the most common ... See full document
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Mutations of KRAS NRAS BRAF predict cetuximab resistance in metastatic colorectal cancer patients
... single mutations, complex mutational patterns were frequently detected in mCRC ...complex mutations responded to cetuximab-based ...BRAF/NRAS mutations showed weak tumor regression ...complex ... See full document
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Original Article Increased expression of Rab5A predicts metastasis and poor prognosis in colorectal cancer patients
... Abstract: Rab5A is reported to correlate with cancer development and progression. The purpose of this study is to explore the association between Rab5A expression and the clinical characteristics of ... See full document
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Original Article TGFBI protein high expression predicts poor prognosis in colorectal cancer patients
... of colorectal cancer. Furthermore, the survival rates of the patients with high TGFBI expression were significantly lower than those of the patients with low TGFBI ...in colorectal ... See full document
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