[PDF] Top 20 Phosphorylation of Rubella Virus Capsid Regulates Its RNA Binding Activity and Virus Replication
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Phosphorylation of Rubella Virus Capsid Regulates Its RNA Binding Activity and Virus Replication
... Rubella virus is an enveloped positive-strand RNA virus of the family ...a capsid and two membrane-spanning glycoproteins, E2 and E1. During virus assembly, the capsid ... See full document
8
Protein Phosphatase 1α Interacts with Venezuelan Equine Encephalitis Virus Capsid Protein and Regulates Viral Replication through Modulation of Capsid Phosphorylation
... viral replication observed at 8 hpi ...virion-associated RNA in 1E7-03-treated cells across each time point ...intracellular RNA was not affected in the same manner (Fig. 2E). Intracellular ... See full document
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Host Acyl Coenzyme A Binding Protein Regulates Replication Complex Assembly and Activity of a Positive-Strand RNA Virus
... positive-strand RNA viruses. Many plant positive-strand RNA viruses form vesicular replication com- plexes in infected host ...spherular replication complexes in mitochondria (66) and ... See full document
12
Phosphorylation of the Brome Mosaic Virus Capsid Regulates the Timing of Viral Infection
... 6 Phosphorylation of the BMV capsid affects the capsid-RNA ...of RNA sequences contacting the capsid within mock- treated and CIP-treated virions identified by CLIP-seq ...the ... See full document
13
Phosphorylation of Hepatitis C Virus RNA Polymerases Ser29 and Ser42 by Protein Kinase C-Related Kinase 2 Regulates Viral RNA Replication
... HCV RNA replication in cell culture ...the replication of HCV sub- genomic and genomic ...NS5B phosphorylation site mutations on RdRp ... See full document
13
Identification of a Ca2+-Binding Domain in the Rubella Virus Nonstructural Protease
... - binding affinity of the Ca 2⫹ -binding loop, the protease is pos- sibly inactive in the cytosol and must be associated with the late endosomal or lysosomal membrane before encountering Ca 2⫹ ... See full document
12
Rubella Virus Capsid Protein Interacts with Poly(A)-Binding Protein and Inhibits Translation
... because RNA replication and vi- rus assembly are confined to specific intracellular sites, it is tempting to speculate that if the capsid-mediated translational inhibition is also localized, the ... See full document
11
The Rubella Virus Capsid Protein Inhibits Mitochondrial Import
... Rubella virus (RV) is a human pathogen that causes severe birth defects (reviewed in reference ...between virus proteins and host cell proteins, but little is known about this ...the capsid ... See full document
12
Rubella Virus E2 Signal Peptide Is Required for Perinuclear Localization of Capsid Protein and Virus Assembly
... and replication of RV have been studied ex- tensively (for reviews, see references 5 and ...three virus-encoded structural proteins, and a single molecule of 40S genomic ...The virus genome serves as ... See full document
6
Identification of domains in rubella virus genomic RNA and capsid protein necessary for specific interaction.
... this RNA domain (nucleotides 347 to 375) is responsible for specific interaction with capsid pro- tein, PCR mutagenesis was used to delete the RNA region from nucleotides 376 to ...in capsid ... See full document
7
Characterization of the Zinc Binding Activity of the Rubella Virus Nonstructural Protease
... positive-stranded RNA viruses of animals studied thus far, in only a few cases has insight into the function of this pro- cessing been gained (28, ...for virus replication and ... See full document
8
Phosphorylation of murine SAMHD1 regulates its antiretroviral activity
... the replication of Friend MLV in SAMHD1 KO and WT mice but could not detect any differences in Friend MLV replication capacity in vivo ...reporter virus at a MOI of 1 and analyzed the accumulation of ... See full document
15
Analysis of Rubella Virus Capsid Protein-Mediated Enhancement of Replicon Replication and Mutant Rescue
... Rubella virus (RUB), the causative agent of rubella and congenital rubella syndrome, is the sole member of the genus Rubivirus in the family Togaviridae of animal viruses (for a review, see ... See full document
9
Glyceraldehyde 3-Phosphate Dehydrogenase Negatively Regulates the Replication of Bamboo Mosaic Virus and Its Associated Satellite RNA
... positive-strand RNA viruses (1, 24), including Bamboo mosaic virus ...satBaMV RNA replication, have not yet been ...negatively regulates the accumulation of BaMV and its ... See full document
12
Analyses of Phosphorylation Events in the Rubella Virus Capsid Protein: Role in Early Replication Events
... the RNA binding region of the capsid ...the phosphorylation state of CapP5D, a capsid mu- tant in which serine residues 45, 46, 48, and 52 and threonine 47, all within the RNA ... See full document
9
Optimal Replication Activity of Vesicular Stomatitis Virus RNA Polymerase Requires Phosphorylation of a Residue(s) at Carboxy-Terminal Domain II of Its Accessory Subunit, Phosphoprotein P
... that phosphorylation of specific residues within domain I of P protein of Indiana sero- type VSV is not essential for the in vivo replication function of the protein (45, ...transcription activity of ... See full document
8
Phosphorylation of a Conserved Tyrosine in the Papillomavirus E2 Protein Regulates Brd4 Binding and Viral Replication
... Brd4 binding to the TAD (52, 53). The presence of Brd4 at a promoter and its recruitment of P-TEFb is required for transcriptional elongation by RNA polymerase ...promoter activity, resulting ... See full document
13
Interactions between Rubella Virus Capsid and Host Protein p32 Are Important for Virus Replication
... and RNA synthesis. To better understand how the lack of a stable capsid-p32 interaction leads to replication defects, we chose to examine early and late steps in the virus life ...genomic ... See full document
14
FUSE Binding Protein 1 Interacts with Untranslated Regions of Japanese Encephalitis Virus RNA and Negatively Regulates Viral Replication
... J-R2A RNA and firefly luciferase RNA as the transfection ...luciferase activity were noted ...second replication peak, as reported for other flaviviral replicon ...viral RNA ... See full document
9
Autoantigens interact with cis-acting elements of rubella virus RNA.
... RV RNA replication (1, 24, ...the replication of RV RNA was first hypothesized when it was noted that actinomycin D has profound inhibitory effects on RNA replication and accumu- ... See full document
9
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