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[PDF] Top 20 Plasma complement factor H is associated with disease activity of patients with ANCA associated vasculitis

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Plasma complement factor H is associated with disease activity of patients with ANCA associated vasculitis

Plasma complement factor H is associated with disease activity of patients with ANCA associated vasculitis

... in patients with MPO-ANCA- positive ...alternative complement pathway is required for induction of necrotizing and crescentic glomerulonephritis by anti-MPO IgG ...in patients with MPO-AAV [7, ... See full document

9

Delta Neutrophil Index Is Associated with Vasculitis Activity and Risk of Relapse in ANCA Associated Vasculitis

Delta Neutrophil Index Is Associated with Vasculitis Activity and Risk of Relapse in ANCA Associated Vasculitis

... between patients with above and below the cut-off of DNI as described in Supplementary Table 1 (only online) by under the Korean Drug Utilization Review (DUR) ...of disease activity attributable to ... See full document

9

Endothelial progenitor cells are differentially impaired in ANCA associated vasculitis compared to healthy controls

Endothelial progenitor cells are differentially impaired in ANCA associated vasculitis compared to healthy controls

... Fifty-three patients (mean age 58 ± 15 years) with diagnosed ANCA-associated vasculitis (Table 1) and 29 age-matched healthy volunteers were enrolled (mean age 58 ± 9 ...Nine patients ... See full document

7

Is serum HMGB1 a biomarker in ANCA associated vasculitis?

Is serum HMGB1 a biomarker in ANCA associated vasculitis?

... AAV patients and HC were matched for age ...AAV patients were evaluated for HMGB1 levels, disease activity using the third version of the Birmingham Vas- culitis Activity Score (BVAS) ... See full document

9

Neutrophil to lymphocyte ratio at diagnosis can estimate vasculitis activity and poor prognosis in patients with ANCA-associated vasculitis: a retrospective study

Neutrophil to lymphocyte ratio at diagnosis can estimate vasculitis activity and poor prognosis in patients with ANCA-associated vasculitis: a retrospective study

... in patients with systemic ...be associated with disease activity and prognosis in Takayasu arteritis, Behcet disease, Kawasaki vasculitis and Henoch Schonlein purpura ...in ... See full document

7

The characterisation and determinants of quality of life in ANCA associated vasculitis

The characterisation and determinants of quality of life in ANCA associated vasculitis

... reflects disease activity; however, this study reinforces a previous cross-sectional study that also failed to detect a significant association between BVAS and fatigue ...of disease activity ... See full document

6

Granulomatosis with polyangiitis: a 17 year experience from a tertiary care hospital in Pakistan

Granulomatosis with polyangiitis: a 17 year experience from a tertiary care hospital in Pakistan

... on ANCA associated vasculitis from the developing ...105 patients. They also assessed the disease activity and damage through the Birmingham Vasculitis Activity ... See full document

6

Platelets are activated in ANCA associated vasculitis via thrombin PARs pathway and can activate the alternative complement pathway

Platelets are activated in ANCA associated vasculitis via thrombin PARs pathway and can activate the alternative complement pathway

... 27 patients with AAV, who achieved complete remission at least 3–6 months after the initiation of immuno- suppressive therapy, were also collected at their regular ambulatory ...AAV patients in the current ... See full document

10

Automated interpretation of ANCA patterns   a new approach in the serology of ANCA associated vasculitis

Automated interpretation of ANCA patterns a new approach in the serology of ANCA associated vasculitis

... of ANCA is characterized by human bias and high variability due to methodological issues such as differing fixation protocols for neutrophils and fluorescence microscopy components (for example, lamps, filters, ... See full document

11

Hallmark trials in ANCA-associated vasculitis (AAV) for the pediatric rheumatologist

Hallmark trials in ANCA-associated vasculitis (AAV) for the pediatric rheumatologist

... achieve disease remission and minimize medication tox- ...of disease activity on the BVAS and no more than 1 item indicating persistent disease activity (BVAS < ...positive ... See full document

15

Epitope specificity determines pathogenicity and detectability in ANCA associated vasculitis

Epitope specificity determines pathogenicity and detectability in ANCA associated vasculitis

... necrotizing vasculitis is caused by immune-mediated inflammation of the vessel wall and is diagnosed in some cases by the presence of myeloperoxidase-specific antibodies ...in ANCA epitope specificity ... See full document

12

ANCA-associated vasculitis in childhood: recent advances

ANCA-associated vasculitis in childhood: recent advances

... adult patients demonstrated its non-inferiority to CYC for remission induction in AAV [48, ...for patients with relapsing disease ...of patients were off steroids (but still on mycophenolate) ... See full document

9

Anaemia is an essential complication of ANCA-associated renal vasculitis: a single center cohort study

Anaemia is an essential complication of ANCA-associated renal vasculitis: a single center cohort study

... Two patients already had renal dysfunction and 8 patients showed mild anaemia (haemoglobin ...the disease onset. Eighteen patients had a history of hyper- tension, 2 had a history of diabetes, ... See full document

8

Long term outcome of patients with ANCA associated vasculitis treated with plasma exchange: a retrospective, single centre study

Long term outcome of patients with ANCA associated vasculitis treated with plasma exchange: a retrospective, single centre study

... the patients’ characteristics differed, our results regarding long-term patient survival were generally similar to or slightly better than those described in the long-term follow-up of the MEPEX trial (median ... See full document

6

Rituximab in the treatment of refractory or relapsing eosinophilic granulomatosis with polyangiitis (Churg Strauss syndrome)

Rituximab in the treatment of refractory or relapsing eosinophilic granulomatosis with polyangiitis (Churg Strauss syndrome)

... 160 patients with ANCA-associated vasculitides regu- larly attending the Department of Rheumatology at the University Medical Center for Vasculitides in Freiburg, Germany, were screened for this ... See full document

9

Progress in treatment of ANCA associated vasculitis

Progress in treatment of ANCA associated vasculitis

... survival factor, is a further ...receptor. Patients with active untreated GPA have signifi cantly higher serum BLyS levels than healthy controls ...of plasma cells and BLyS seems to protect lymphoid ... See full document

12

Microscopic polyangiitis associated with thymic tumor: a case report and review of the literature

Microscopic polyangiitis associated with thymic tumor: a case report and review of the literature

... and ANCA production, but in our patient’s case a thymectomy could not be per- formed because of her advanced ...of associated autoimmune syn- dromes, and in some cases it causes disease progression ... See full document

7

Fatigue in patients with inflammatory bowel disease is associated with distinct differences in immune parameters

Fatigue in patients with inflammatory bowel disease is associated with distinct differences in immune parameters

... The CIS is a 20-item patient-reported validated instrument measuring severity of fatigue, motivation, activity level and concentration. The severity of fatigue, measured with the sub- scale “fatigue”, was used as ... See full document

8

Alpha-1 Antitrypsin Deficiency Presenting with MPO-ANCA Associated Vasculitis and Aortic Dissection

Alpha-1 Antitrypsin Deficiency Presenting with MPO-ANCA Associated Vasculitis and Aortic Dissection

... Involvement of large vessels is uncommon in AAV, while extracranial GCA has been commonly observed in patients with cranial GCA [7]. In this patient with a type B aortic dissection and recent MPO-AAV, a more ... See full document

5

Clinical Management of Uveitis in Systemic
Rheumatic Autoimmune Diseases in Adults

Clinical Management of Uveitis in Systemic Rheumatic Autoimmune Diseases in Adults

... The eye has a particular relationship with the immune system which is known as “immune privilege” and involves physical barriers, immunosuppressive factors and protein antigens [1]. The term “uveitis” is often used to ... See full document

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