[PDF] Top 20 Polymorphisms of Toll-Like Receptor 4 as a Risk Factor for Periodontitis: Meta-Analysis
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Polymorphisms of Toll-Like Receptor 4 as a Risk Factor for Periodontitis: Meta-Analysis
... ducted meta-analyzes on the association of TLR4 polymorphisms with periodontitis [14, 33, 34] are compared with present findings in Table ...first meta- analysis by Ozturk et ...these ... See full document
12
Toll-like receptor 4 Asp299Gly and Thr399Ile polymorphisms: New data and a meta-analysis
... UC) risk in many other diverse ...several meta-analyses provided evidence that the Asp299Gly SNP is associated with CD and IBD in Caucasians ...our meta-analysis indicate a significant ... See full document
15
Association between Toll Like Receptor 4 (Thr399Ile and Asp299Gly), Toll Like Receptor 2 196 174 Deletion Polymorphisms with cryptosporidiosis
... Cryptosporidium spp. is a Coccidian enteric parasite causing severe diarrhea in immu- no-compromised patients, such as human immunodeficiency virus (HIV) infected pa- tients and organ transplant recipients [1]-[5]. This ... See full document
12
Role of polymorphisms of toll like receptor (TLR) 4, TLR9, toll interleukin 1 receptor domain containing adaptor protein (TIRAP) and FCGR2A genes in malaria susceptibility and severity in Burundian children
... of toll-like receptors (TLRs) ...extracellular receptor modules and initiating inflammatory signalling pathways through an intracellular domain ...crosis factor (TNF) that should favour the ... See full document
8
Association between toll-like receptors 9 (TLR9) gene polymorphism and risk of pulmonary tuberculosis: meta-analysis
... The SNP rs352139 is located in the intron of TLR9 gene (Figure 2). TIR domain consists of the end of exon 1, intron and a part of exon 2 which contains SNP rs352139. It is the only polymorphism located in the in- tron ... See full document
10
Association of coronary artery disease with toll-like receptor 4 genetic variants: A meta-analysis
... The studies included were required to meet all of the fol- lowing conditions: 1. involving human subjects; 2. pub- lished in peer-reviewed journals in Chinese or English; 3. employing a case-control design; 4. no ... See full document
8
Toll like receptor polymorphisms in malaria endemic populations
... increased risk of severe malaria ...as Toll-Interleukin-1 Receptor domain-containing Adaptor Protein, TIRAP) is a down- stream adaptor protein common to both the TLR2 and TLR4 signaling pathways ... See full document
10
Effects of human Toll-like receptor 1 polymorphisms on ageing
... It could be shown that PBMC from old German indivi- duals with the TLR1pos 743AG genotype released signifi- cantly more anti-inflammatory IL-1Ra than aged individuals with the TLR1neg 743AA genotype (Figure 1). There are ... See full document
9
Toll-Like Receptor 4 Gene (TLR4), but Not TLR2, Polymorphisms Modify the Risk of Tonsillar Disease Due to Streptococcus pyogenes and Haemophilus influenzae
... the receptor (2). They have been associated with receptor hypore- sponsiveness in macrophages, epithelial cells, and peripheral blood mononuclear cells, resulting in impaired TLR4 signaling ...TLR ... See full document
6
Association of Toll-Like Receptor (TLR) Gene Polymorphisms with Asthma: A Review
... increased risk for asthma in a case-control study and the family-based analysis 40 ...single-nucleotide polymorphisms in TLR2 subfamily ...reduced risk of asthma when compared with those with ... See full document
11
Association of Toll-Like Receptor (TLR) Gene Polymorphisms with Asthma: A Review
... increased risk for asthma in a case-control study and the family-based analysis 40 ...single-nucleotide polymorphisms in TLR2 subfamily ...reduced risk of asthma when compared with those with ... See full document
11
The Toll Like Receptor 4 Antagonist Eritoran Protects Mice from Lethal Filovirus Challenge
... S1, analysis of cytokine/chemokine levels using a multiplex bead-based assay resulted in distinctive patterns being observed between placebo- and eritoran-treated ...necrosis factor alpha (TNF- ␣ ) was the ... See full document
10
Recombinant human proteoglycan 4 reduces phagocytosis of urate crystals and downstream nuclear factor kappa B and inflammasome activation and production of cytokines and chemokines in human and murine macrophages
... at 4 h, MSU crystals have accumulated in the Prg4 −/− macro- phages compared to the wildtype counterparts by 24 h, with approximately 3 times the number of intracellular MSU crystals in Prg4 −/− macrophages ... See full document
16
Genes associated with variation in longevity and fecundity in sheep
... In humans, two TLR4 missense mutations, Asp299Gly and Thr399Ile, have been associated with longevity (Balistreri et al., 2009). These mutations were found in LRR11 and 15, respectively (see table 6.2) and both of the ... See full document
255
TLR4 rs41426344 increases susceptibility of rheumatoid arthritis (RA) and juvenile idiopathic arthritis (JIA) in a central south Chinese Han population
... Haplotypes were predicted for 6 SNPs using PLINK 1.09 (http://pngu.mgh.harvard.edu/~purcell/plink/). Ten haplo- types in RA and JIA separately with a frequency > 1% were predicted in both cases and controls accounting ... See full document
8
Analysis of the effects of Macrophage Migration Inhibitory Factor (MIF) on the activation of Toll like receptor 4 (TLR4)
... 10 4 cells/mL in a 96-well plate and then stimulated with LPS (from Escherichia coli O111:B4 L4391, Sigma Aldrich), TNF α (Biolegend), TsMIF1, MmMIF1 or pharmacological inhibitors such as Polymyxin B sulfate (PMB) ... See full document
78
The relationship between TRAF6 and tumors
... necrosis factor receptor; TRAFs: Tumor necrosis factor receptor- related factors; TNFSF: Tumor necrosis factor superfamily; TLR/ILR: Toll-like/ interleukin-1 ... See full document
12
Toll-like receptor-4 as a predictor of clinical outcomes of estrogen receptor-negative breast cancer in Saudi women
... TLR-4 has been reported as an indicator of various types of cancers. In the present study, we investigated whether the expression of TLR-4 in breast cancer has any prognostic value in the Saudi population ... See full document
10
Signal transduction by the lipopolysaccharide receptor, Toll like receptor 4
... the receptor complex (as described ...the receptor complex and association of IRAK with ...growth factor-b-activated kinase), which is constitutively associated with its adapter protein, ... See full document
10
Polymorphisms of Toll-like receptor-4 and CD14 in systemic lupus erythematosus and rheumatoid arthritis
... The functional variant CD14*T that enhances the pro- moter activity and increases the CD14 expression was markedly associated to SLE susceptibility in the present study but was not correlated to both disease activity and ... See full document
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