[PDF] Top 20 Preservation of Peripheral T Follicular Helper Cell Function in HIV Controllers
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Preservation of Peripheral T Follicular Helper Cell Function in HIV Controllers
... with HIV envelope potential T cell epitope (PTE) peptide pools (1 g/ml; NIH AIDS Reagent Program) for 6 h in complete RPMI medium in the presence of costimulating antibodies CD28/49d (BD ... See full document
14
Early Preservation of CXCR5+ PD-1+ Helper T Cells and B Cell Activation Predict the Breadth of Neutralizing Antibody Responses in Chronic HIV-1 Infection
... in HIV-1 infection is dependent on the early preservation of CXCR5 ⫹ (PD-1 ⫹ ) CD4 ⫹ T ...⫹ T cell help ...early HIV-1 infection the subjects from the narrow group suffer a def- ... See full document
12
Streptococcal superantigen‐induced expansion of human tonsil T cells leads to altered T follicular helper cell phenotype, B cell death and reduced immunoglobulin release
... B cell IgM responses in a manner that required altered activity of T cells, raising the possibility of either reduced T helper cell function or an increase in T suppressor ... See full document
13
Emerging Role of Follicular T helper cells in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis.
... CD4 T cells with B cell helper function during chronic HIV ...C., Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center ... See full document
16
The role of follicular helper CD4 T cells in the development of HIV 1 specific broadly neutralizing antibody responses
... CD4 T-cell lineages [26, ...regulatory T cells [28, ...the T cell zones sur- rounding the lymphoid follicles [30] and continues at the follicular T-B border with cognate ... See full document
10
Increased Circulating T Follicular Helper Cells in Iranian Children with Type I Diabetes
... CD8+ T cells are main factors of β-cell destruction, B cells and autoantibodies may also play a critical role in T1D development and ...significant preservation of β-cell function in ... See full document
7
Peripheral T Follicular Helper Cells Are the Major HIV Reservoir within Central Memory CD4 T Cells in Peripheral Blood from Chronically HIV-Infected Individuals on Combination Antiretroviral Therapy
... construct HIV-1 NL4-3/Ba-L-EGFP has been previously de- scribed by our group ...(31). HIV stocks were prepared by harvesting the supernatant of 293T cells transfected with ...h. Cell culture ... See full document
11
Enhanced IL 6/phosphorylated STAT3 signaling is related to the imbalance of circulating T follicular helper/T follicular regulatory cells in patients with rheumatoid arthritis
... the peripheral diarthrodial joints, leading to progressive destruction of articular cartilage and bones, culminating in severe pain and disability ...processes, follicular helper T (Tfh) cells ... See full document
9
A High Frequency of HIV Specific Circulating Follicular Helper T Cells Is Associated with Preserved Memory B Cell Responses in HIV Controllers
... at HIV (23, 24, ...that HIV controllers can develop potent memory B cell responses without high NAb titers (40, 55, 56) and that assessing the “silent” memory B cell compartment is ... See full document
22
HIV and T follicular helper cells: a dangerous relationship
... of HIV-1, multiple mecha- nisms enable it to evade antibody binding and replicate at ...CD4 T cells that are required to help the B cell response, a high mutation rate that allows the rapid emergence ... See full document
5
Changes in Follicular Helper T Cells in Idiopathic Thrombocytopenic Purpura Patients
... the function of TFH cell ...and peripheral blood ...activated T cells, inhibiting excessive proliferation of TFH cells in GC [8, 19, 20, ...TFH cell, decrease function of TFH by ... See full document
10
T follicular helper cells in human efferent lymph retain lymphoid characteristics
... the follicular mantle of the B cell follicle, and follow- ing secondary challenge, some of these follicular mantle Tfh exit into the subcapsular sinus of the LNs (23), suggesting a potential ... See full document
17
Public T cell receptors confer high avidity CD4 responses to HIV controllers
... controlled HIV infection, with both TCR chains showing a significant degree of motif conserva- ...8 controllers (75%) ...the HIV- specific repertoire were shared by 2–4 patients (13, 14, 39, ... See full document
17
Early T Follicular Helper Cell Responses and Germinal Center Reactions Are Associated with Viremia Control in Immunized Rhesus Macaques
... blood cell lysis, and stored frozen in FBS–10% DMSO as previously described ...The cell suspension was then passed through a 70- m cell strainer and washed with 30 ml of R10 medium (RPMI 1640, 1 ⫻ ... See full document
22
Modulation of peripheral T-cell function by interleukin-7 in rheumatoid arthritis
... on cell surfaces ...+ T cells and natural killer (NK) cells, but not on mature hu- man B ...blood T cells, respond to IL-7 by spontaneous proliferation ...+ T cells ...+ T cells in the ... See full document
13
Distribution of distinct subsets of circulating T follicular helper cells in Kawasaki disease
... CXCR5+ T cells are well-known as a distinct sub- set of CD4+ T cells, which have the ability to induce B cell proliferation, to differentiate to plasma cells and to secret ...naïve T cells via ... See full document
9
Circulating T follicular regulatory and helper cells have memory like properties
... independently. Follicular Tregs (Tfr cells) inhibit antibody production, whereas follicular Th cells (Tfh cells) stimulate ...Tfh cell activation and production of cytokines, including IL-21, and ... See full document
15
T4+ T helper cell function in vivo: differential requirement for induction of antiviral cytotoxic T-cell and antibody responses.
... Depletion of T4+ cells caused a pronounced suppression of antiviral antibody response 20-fold decrease but had minimal effect on virus-specific CTL response 90% of T helper cells, anti-L[r] ... See full document
5
Alterations in cytotoxic and helper T cell function after infection of T cell clones with human T cell leukemia virus, type I
... this helper function became independent of DPw2-stimulation and persisted even when the cytotoxic activity was ...OKT4+ T cell clone thus could simultaneously manifest both cytotoxic and ... See full document
9
CD57+ T-cells are a subpopulation of T-follicular helper cells in nodular lymphocyte predominant Hodgkin lymphoma
... of T-follicular helper (TFH) cells, PD-1 and ...+ T-cells are also positive for PD-1, whereas roughly half of the PD-1 + T-cells are CD57 + ... See full document
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