[PDF] Top 20 Prevention of Early Postoperative Decline (PEaPoD): protocol for a randomized, controlled feasibility trial

... outcome: feasibility To best evaluate the potential effect of a neurocognitive training program on the development of postoperative delirium and POCD, a large randomized controlled ... See full document

... Methods/Design: This open-label, interventional study involves a parallel randomized controlled trial design with three arms (two intervention arms and a control group) over a nine-month period. ... See full document

... The interventional treatment will be administered to pa- tients under advanced hemodynamic monitoring in the setting of a fully equipped cardiac surgical operation room. This enables immediate detection and treatment of ... See full document

... CINV. Early evidence suggesting potential efficacy of the NK-1 receptor antagonists (using pilot drugs) as prophylaxis against PONV was noted in two studies of patients undergoing gynecologic surgery [14] ...the ... See full document

... the feasibility and safety of moderate dietary restrictions (alone or in combination with exercise) for postpartum weight loss ...recent trial based on ... See full document

... Demographic data such as age, sex, ethnicity, race, and body mass index will be recorded. Patient comor- bid conditions, surgery, and anesthetic drugs will be obtained from the patient’s medical records as well as from ... See full document

... recruitment early was related to funding and clinical reasoning that was informed by a) evidence-based guidelines that recommend interventions of at least 60 hrs for individuals presenting with high levels of ... See full document

... Unfortunately the trials were small, 27 patients per group. Although a meta-analysis offers compensation for this flaw, sample size still be too small for detecting a difference when events occur infrequent. With these ... See full document

... several randomized controlled trials showing evidence of benefit by signifi- cantly reducing the incidence of exacerbations of COPD of all severities ...rapid decline in lung function, re- duced ... See full document

... the early postoperative phase, preoperative muscle dys- functions such as decreased trunk muscle strength and imbalances between trunk extensor and flexor muscles have been reported up to 3 months after ... See full document

... This trial is a prospective, randomized controlled trial that will test the superiority of bilateral PNB with ...be randomized to receive either bilateral PNB with ...of ... See full document

... single-centre randomized controlled parallel group trial, in a British university ...concentrations, early and late transfusion rates, infectious and cardiovascular complications, mobility and ... See full document

... and postoperative nadir is around 2 ...for early [1,2] and late [3] postoperative ...found postoperative [Hb] < 10 g/dl to be an inde- pendent risk factor for poor mobility in previously ... See full document

... This trial has potential ...a randomized controlled trial should be blinded but this is not always feasible in non-pharmacological trials ...this trial, the outcome assessors and ... See full document

... a randomized trial to establish the efficacy of a theory- based telephone-delivered short Patient Self-Management Support intervention in post-TKA patients ...Rosal trial by using an MI-based ... See full document

... The new procedure consists of the application of a for- mula, in either liquid or spray, which contains 95% extra virgin olive oil. This product will have the same appear- ance as the hyperoxygenated fatty acid, using ... See full document

... All statistical analyses will be performed using IBM SPSS software using intention-to-treat and per protocol ana- lyses. Nominal data will be described by frequencies and percentages, and correlations will be ... See full document

... study protocol (a list of ethic committee is available in Additional file ...1). Protocol modifications will be reported to each relevant part including national and local institutional review boards and ... See full document

... Participants assigned to the social interaction group will receive six visits over the same time period as the phys- ical activity group. The sessions will also be matched for time (approximately 45 minutes). The aim of ... See full document

... Some sections of the CRFs act as source data for the trial and are completed directly by the relevant research personnel. A few sections, such as vaccination, are tran- scribed from the Infant Welfare Card for the ... See full document