[PDF] Top 20 Protein interactions during coronavirus assembly.
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Protein interactions during coronavirus assembly.
... viruses, coronavirus assembly is presum- ably dependent on protein localization and protein-protein as well as protein-RNA ...bovine coronavirus (BCV) as a model to study ... See full document
7
Palmitoylations on Murine Coronavirus Spike Proteins Are Essential for Virion Assembly and Infectivity
... in assembly, they are nonetheless key contributors of native virion structure and robust virus particle ...entry. During the enveloped-virus entry process, there is a concerted refolding of the surface ... See full document
10
Analyses of Coronavirus Assembly Interactions with Interspecies Membrane and Nucleocapsid Protein Chimeras
... S protein than did those of ...S protein approaching those of the wild type. Thus, the level of S-protein incorporation into various SARS-CoV M- protein chimeras was consistent with their ... See full document
12
Animal Origins of the Severe Acute Respiratory Syndrome Coronavirus: Insight from ACE2-S-Protein Interactions
... S protein specifically, with approximately 2 nM affinity ...S protein raises a protective neu- tralizing antibody response in mice, and anti-S-protein anti- bodies that block ACE2 association protect ... See full document
9
The Minor Capsid Protein VP11 of Thermophilic Bacteriophage P23-77 Facilitates Virus Assembly by Using Lipid-Protein Interactions
... of protein stabilization at high tempera- tures (50, 51, ...the protein disulfide oxidoreductase (53), an enzyme spe- cifically found in thermophiles, including the P23-77 host ...-helical protein ... See full document
11
Myristate-protein interactions in poliovirus: interactions of VP4 threonine 28 contribute to the structural conformation of assembly intermediates and the stability of assembled virions.
... 12 0022-538X/92/126849-09$02.00/0 Copyright C 1992, American Society for Microbiology Myristate-Protein Interactions in Poliovirus: Interactions of VP4 Threonine 28 Contribute to the Str[r] ... See full document
9
A Coronavirus E Protein Is Present in Two Distinct Pools with Different Effects on Assembly and the Secretory Pathway
... (E) protein plays roles in assembly, virion release, and ...E protein during infection are still ...E protein suggest that it assembles into a ...virus during infection. The E ... See full document
11
Residues on Adeno-associated Virus Capsid Lumen Dictate Interactions and Compatibility with the Assembly-Activating Protein
... AAP protein sequences of AAP80 and AAP81 (Anc81VP- compatible AAPs, blue bars) to those of AAP2, AAP8, and AAP82 (Anc81VP- incompatible AAPs, red bars), six residues emerge that share identity only within their ... See full document
16
Nucleocapsid protein-dependent assembly of the RNA packaging signal of Middle East respiratory syndrome coronavirus
... the assembly of the viral ...the assembly of VLPs ...M protein and the pack- aging signal, a coexpressed RNA fragment carrying the viral packaging signal can be packaged into VLPs in the absence of N ... See full document
12
Host Protein Interactions with the 3′ End of Bovine Coronavirus RNA and the Requirement of the Poly(A) Tail for Coronavirus Defective Genome Replication
... lular protein involved in alternative splicing of cellular mRNAs, binds the MHV minus-strand complement of the leader sequence ...binding protein (PTB), also known as heterogeneous nuclear RNP I (hnRNP I), ... See full document
13
Coronavirus envelope protein: current knowledge
... E protein is unique in that it can form homo- typic interactions, which allows it to oligomerise and generate an ion-channel protein known as a viroporin [135, ... See full document
22
Systematic Assembly of a Full-Length Infectious Clone of Human Coronavirus NL63
... genus Coronavirus (14, 30, 37). Currently, the Coronavirus genus is further divided into three primary groups based upon serological and phylogenetic ...envelope protein (E) of ⬃ 9 ...nucleocapsid ... See full document
10
Severe Acute Respiratory Syndrome Coronavirus Protein 6 Accelerates Murine Coronavirus Infections
... membranes during the eclipse phase (51), nascent virion pro- teins incorporate into ER membranes, and ER-Golgi interme- diate compartment membranes are then acquired to form new virion coats ...several ... See full document
10
Intracellular Localization and Protein Interactions of the Gene 1 Protein p28 during Mouse Hepatitis Virus Replication
... Replicase protein precursors and mature products are thought to mediate the formation and function of viral replication complexes on the surfaces of intracellular double-membrane ...the coronavirus mouse ... See full document
12
Analysis of Constructed E Gene Mutants of Mouse Hepatitis Virus Confirms a Pivotal Role for E Protein in Coronavirus Assembly
... 3 RevI, to check for the possible presence of mutations in this protein, which potentially interacts directly with the E protein (4, 42). No mutations were found in any of the M genes of these revertants. ... See full document
10
Interactions of the Oas-Rnase L Pathway With Murine Coronavirus
... of protein synthesis and finally apoptosis ...accessory protein, non-structural protein 2 (ns2), a 2’,5’-phosphodiesterase (PDE) that cleaves 2-5A thereby preventing RNase L activation (Zhao et ... See full document
135
Interactions of SARS Coronavirus Nucleocapsid Protein with the host cell proteasome subunit p42
... infection. Interactions between viruses and UPP have recently been ...X protein (HBX) has been demonstrated to target the proteasome complex after viral entry into the cell ...Tat protein was shown ... See full document
8
Assembly of the Coronavirus Envelope: Homotypic Interactions between the M Proteins
... M protein, with its three transmembrane domains (a, b, and c) indicated, is shown on ...M protein A2A3 (Rescue) are indicated at the upper right and ...M protein ⌬RK, which was slightly less ... See full document
12
A Conserved Domain in the Coronavirus Membrane Protein Tail Is Important for Virus Assembly
... virus assembly, the TM1 changes are apparently providing some advantage for the mutant M proteins containing the 5 ⬘ A ...M interactions and that the second-site changes in TM1 promote new inter- actions ... See full document
11
Coronavirus Particle Assembly: Primary Structure Requirements of the Membrane Protein
... phenotypically silent 19-base tag in gene 4 (16) (Fig. 10A). Of 24 recombinants arising from four independent experiments with the D2 mutant donor RNA, all of which had repaired the N-gene deletion, none contained either ... See full document
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