[PDF] Top 20 Protein-RNA interactions: a structural analysis
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Protein-RNA interactions: a structural analysis
... the protein–RNA complexes reveals some interesting differences (Table ...in protein synthesis (principally the tRNA amino synthetases) have RNA binding sites more than ...the RNA ... See full document
12
Computational modeling suggests dimerization of equine infectious anemia virus Rev is required for RNA binding
... The QMEAN [47,48] and ProQ2 [49] servers were used to evaluate models for consistency with known protein structural features. These are among the top performing model quality assessment servers, routinely ... See full document
12
Analysis of astrovirus serotype 1 RNA, identification of the viral RNA-dependent RNA polymerase motif, and expression of a viral structural protein.
... A region of 600 nt encoding the RDRP motif from three of the other available human astrovirus serotypes demonstrated a high degree of homology at the nucleotide and amino acid levels Fig[r] ... See full document
7
Visualization of Protein-RNA Interactions in Cytoplasmic Polyhedrosis Virus
... Comparison with other dsRNA viruses and functional im- plications. The single-shelled capsid of CPV is unique and contrasts with the double- or triple-shelled capsids of other members in the Reoviridae. In the mammalian ... See full document
6
Defining the RNA-Protein Interactions in the Trypanosome Preribosomal Complex
... for protein-RNA interactions but also show that 5S rRNA enhances the protein-protein interactions that are of potential functional significance for the stabilization and ... See full document
8
Interactions between the Structural Domains of the RNA Replication Proteins of Plant-Infecting RNA Viruses
... FIG. 1. (A) Locations of insertion mutations and their replication pheno- types in protoplasts. The box represents the 1a open reading frame. The lightly shaded N-terminal portion contains sequences putatively involved ... See full document
10
Analysis of the natively unstructured RNA/protein-recognition core in the Escherichia coli RNA degradosome and its interactions with regulatory RNA/Hfq complexes
... complex, RNA contributes to the intricate regulatory processes that are mounted in response to stress, environmental changes or as part of intricate programs of ...regulatory RNA can affect the expression ... See full document
16
Expression, purification and structural analysis of the Pyrococcus abyssi RNA binding protein PAB1135
... Af2318 protein is present in the same operon as RNase P subunit Rpp30 ...Sequence analysis has led to the clustering of these proteins in the UPF0201 family ...this protein family show a single α/β ... See full document
8
Evidence for Functional Protein Interactions Required for Poliovirus RNA Replication
... (PV) RNA replication takes place in replication complexes that form de novo in cultured cells after virus in- ...and RNA (reference 11 and references ...viral RNA synthesis, ac- companied by the loss ... See full document
11
Transposable elements modulate human RNA abundance and splicing via specific RNA protein interactions
... To further explore the potential for function in these nonrepetitive TESM occurrences, we considered their conservation using PhyloP (Figure 4C) [47]. Due to the severely different PhyloP backgrounds in the various an- ... See full document
16
Avian oncovirus MH2: molecular cloning of proviral DNA and structural analysis of viral RNA and protein.
... Hence, the restriction mapping, the hybridization data, and the protein analyses suggest that the central region of the MH2 genome contains additional sequences unrelated to virion genes[r] ... See full document
13
Identification of BV/ODV-C42, an Autographa californica Nucleopolyhedrovirus orf101-Encoded Structural Protein Detected in Infected-Cell Complexes with ODV-EC27 and p78/83
... extension analysis was performed to determine the temporal pattern of orf101 ...representative analysis and the first ATG as the putative se- quence for translation initiation shows that all of the TAAG ... See full document
8
Identification and Characterization of Sindbis Virus RNA-Host Protein Interactions
... pathogens, RNA viruses must interact with the host cell machinery to establish and complete their life ...phaviral RNA-protein interactions has not been ...these interactions, in the ... See full document
27
Essential Assembly Factor Rpf2 Forms Novel Interactions within the 5S RNP in Trypanosoma brucei
... TbRpf2 protein leads to a small decrease in the protein levels of the other members of the 5S ...the protein components of the 5S RNP are altered upon loss of TbRpf2, cell extracts from days 0, 1, 2, ... See full document
14
Protein structural analysis: α-helices and their interactions
... in protein conformational analysis, and the Ramachandran plot is now one of the most widely used stereochemical representations in the literature of molecular ... See full document
275
RNA-protein interactions at the 3' end of the hepatitis A virus RNA.
... higher-order structural elements are required for optimal interaction with p38 and other host proteins ...in RNA amplification was established (20, ...higher-order structural elements lo- cated ... See full document
8
Machine Learning for Investigating Post-Transcriptional Regulation of Gene Expression
... post-processing analysis, that include mapping and peak detection, might increase the number of false negatives due to the burden of dealing with splice junctions and the stringent thresholds required for a ... See full document
160
Characterization of Protein-Protein Interactions Critical for Poliovirus Replication: Analysis of 3AB and VPg Binding to the RNA-Dependent RNA Polymerase
... two-hybrid analysis of 3AB and glutaraldehyde cross-linking of detergent-solubilized 3AB (45) suggest that the 3A-N region forms a dimeric structure in the membrane-bound form of this protein as ...(R34P). ... See full document
10
Integrated multifactor analysis explores core dysfunctional modules in autism spectrum disorder
... multifactor analysis exploring dysfunctional modules based on RNA-Seq data from corpus callosum in 6 patients with ASD and 6 normal ...to protein-protein interactions (PPIs) and WGCNA, ... See full document
8
Analysis of protein RNA and protein peptide interactions in Equine Infectious Anemia Virus (EIAV) infection
... HLA-C named alleles (http://www.ebi.ac.uk/imgt/hla/intro.html) (34). MHC I polymorphism occurs primarily in the residues that form the peptide-binding domain, therefore influencing the types of peptides that are ... See full document
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