[PDF] Top 20 Quantitation of Replication-Competent HIV-1 in Populations of Resting CD4+ T Cells
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Quantitation of Replication-Competent HIV-1 in Populations of Resting CD4+ T Cells
... among HIV-infected patients. How- ever, HIV integrates into the genome of CD4 ⴙ T cells, generating pools of long-lived cells that are reservoirs of latent ...of CD4 ⴙ ... See full document
8
A CCR5+ memory subset within HIV 1 infected primary resting CD4+ T cells is permissive for replication competent, latently infected viruses in vitro
... in resting CD4 + T N cells was lower than in resting CD4 + T M cells at 3 days ...R5 HIV-1, even in the resting ... See full document
7
CD161+ CD4+ T Cells Harbor Clonally Expanded Replication Competent HIV 1 in Antiretroviral Therapy Suppressed Individuals
... ⴙ CD4 ⴙ T cells exhibit higher survival and proliferative abilities than CD161 ⴚ CD4 ⴙ T ...⫹ CD4 ⫹ T cells are highly permissive to HIV-1 infection, ... See full document
15
Low level HIV 1 replication and the dynamics of the resting CD4+T cell reservoir for HIV 1 in the setting of HAART
... low-level replication in the setting of HAART to stabilize the latent ...of HIV dynamics by incor- porating latently infected cells in order to understand the effect of low-level viral ... See full document
14
Effects of Microtubule Modulators on HIV-1 Infection of Transformed and Resting CD4 T Cells
... that HIV-1 may utilize the microtubule network for intracellular trafficking (4, 27, ...labeled HIV-1 particles, mul- tiple studies have shown that the preintegration complex (PIC) of ... See full document
5
Latent HIV-1 Infection of Resting CD4+ T Cells in the Humanized Rag2−/− γc−/− Mouse
... type 1 (HIV-1) infection of resting CD4 ⴙ T cells, unaffected by antiretroviral therapy (ART), provides a long-lived reservoir of HIV ...eradicate ... See full document
7
Cell activation and HIV 1 replication in unstimulated CD4+T lymphocytes ingesting exosomes from cells expressing defective HIV 1
... of replication-competent ...in HIV pathogenesis ...defective HIV-1 genomes accumulate in the presence of the block of the replication of infectious ...of resting ... See full document
16
Latent HIV 1 is activated by exosomes from cells infected with either replication competent or defective HIV 1
... + T lymphocytes were activated, infected with the indicated VSV-G psedotyped HIV-1 strains and, after 3 days, put in the upper chamber of a trans-well plate in the presence or not of the indicated ... See full document
17
A stable latent reservoir for HIV 1 in resting CD4+ T lymphocytes in infected children
... their CD4 + T lymphocyte counts while on protease-inhibitor ...his CD4 + cell count was 9 cells/mm 3 and his plasma HIV-1 RNA was 207,554 ...plasma HIV-1 RNA (less ... See full document
10
Exosomal Tat protein activates latent HIV-1 in primary, resting CD4+ T lymphocytes
... + T lymphocytes was poor, with viral reactivation leading to replication-competent virion progeny in 3 of 6 ...purified CD4 + T lymphocytes following coculture for 24 ...latent ... See full document
15
Regulation of Cyclin T1 and HIV-1 Replication by MicroRNAs in Resting CD4+ T Lymphocytes
... in CD4 ⫹ T cells, other targets validated in different tissues have been reported (1, 12, 27, 28, 47, ...and HIV-1 ...known HIV-1 ...of HIV-1 genomic ... See full document
9
SAMHD1: a new contributor to HIV 1 restriction in resting CD4+T cells
... inhibits HIV-1 infection in non- cycling ...with HIV-1 infection and natural control in Europeans and African- Americans ...in HIV-2 infection given that HIV-1 has not ... See full document
5
The role of antigen presenting cells in the induction of HIV 1 latency in resting CD4+ T cells
... in HIV infection and ...non-proliferating CD4 + T-cells were com- pared with APC subpopulations that could not induce latency (plasma- cytoid ...in 1 APC subpopulation were categorized ... See full document
16
HIV 2 infects resting CD4+ T cells but not monocyte derived dendritic cells
... investigated HIV-2 replication in primary CD4+ T lymphocytes, both activated and non-activated, as well as in ...productive HIV-2 infection, using the reference HIV-2 ROD strain, ... See full document
13
HIV Can Establish Latency by Direct Infection of Resting CD4+ T Cells
... of Resting CD4+ T Cells Abstract HIV establishes a latent reservoir in a small pool of resting CD4+ T cells early in the infection of a new ...infected ... See full document
170
Strong Ability of Nef-Specific CD4+ Cytotoxic T Cells To Suppress Human Immunodeficiency Virus Type 1 (HIV-1) Replication in HIV-1-Infected CD4+ T Cells and Macrophages
... for CD4 ⫹ T-cell recognition of virus-infected cells, the endogenous pathway for HLA class II presentation was also identified in some virus infections (20, 33, ...Nef-specific CD4 ⫹ ... See full document
10
Genistein interferes with SDF 1 and HIV mediated actin dynamics and inhibits HIV infection of resting CD4 T cells
... extent, HIV-mediated signal transduction through CXCR4 resembles the chemotactic response mediated by chemokines such as SDF-1, the natural lig- and for CXCR4 ...and HIV require actin dynamics for ... See full document
15
Lymphatic endothelial cells promote productive and latent HIV infection in resting CD4+ T cells
... of CD4+ T cells promoted HIV infection with both a pseudotyped virus and a primary isolate [26], similar exper- iments need to be done with clinical isolates in the future to confirm our ... See full document
14
Evidence for Vpr dependent HIV 1 Replication in Human CD4+CEM NKR T Cells
... human T cell lines A total of 2 × 10 5 cells were incubated with equal amounts of virus at 37°C for three ...times, cells were cul- tured in 24-well plates for 16 ...spinoculation, cells were ... See full document
11
Expression and reactivation of HIV in a chemokine induced model of HIV latency in primary resting CD4+ T cells
... latent HIV infection ...of HIV replication by combining the PKC activator prostratin with ...latent HIV in infected individuals on cART are likely to include combi- natorial approaches and our ... See full document
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