[PDF] Top 20 A quantitative study of tau pathology in eleven cases of chronic traumatic encephalopathy
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A quantitative study of tau pathology in eleven cases of chronic traumatic encephalopathy
... CTE/ADNC cases were compared with ADNC cases not associated with CTE using a two-factor repeated measures ...to study pathological heterogeneity among the 11 CTE cases, the data were analysed ... See full document
36
Chronic traumatic encephalopathy: clinical‐biomarker correlations and current concepts in pathogenesis
... published cases of boxers with neuropatho- logically verified ...two cases involved multifocal patches of neuronal and astrocytic NFT in superficial cortical layers, most frequently at the depths of the ... See full document
22
Co-occurrence of chronic traumatic encephalopathy and prion disease
... Histology and immunohistochemistry were performed essentially as earlier described with modifications [5, 6]. Histological sections from ten brain regions including frontal (FC), temporal (TC), parietal (PC), occipital ... See full document
14
Impact of nutrition on inflammation, tauopathy, and behavioral outcomes from chronic traumatic encephalopathy
... showed chronic inflammatory responses and in- creased tau phosphorylation out to 6 ...and tau phosphorylation or vice versa, in the pathology and behavioral manifesta- ...the study will ... See full document
16
A Review of Traumatic Brain Injury Animal Models: Are We Lacking Adequate Models Replicating Chronic Traumatic Encephalopathy?
... of chronic repetitive brain injuries and neurodegenerative ...mild traumatic brain injury increases cellular markers associated with Alzheimer’s disease ...perivascular tau pathology, neuritic ... See full document
7
Assessing clinicopathological correlation in chronic traumatic encephalopathy: rationale and methods for the UNITE study
... Our study design allows not only for testing the valid- ity of clinical research criteria and the consensus process but also for recognizing sources of error and identifying diagnostic features that best predict ... See full document
14
Variation in TMEM106B in chronic traumatic encephalopathy
... another study who may have developed CTE if they were exposed to ...genotype cases and controls ...current study was conducted in the largest group of CTE cases available to ...these ... See full document
9
Chronic traumatic encephalopathy: a spectrum of neuropathological changes following repetitive brain trauma in athletes and military personnel
... The tau isoform profile and phosphorylation state in CTE are similar to those in AD [35] and the neuronal tau pathology shows immunoreactivity to both three- repeat tau and four-repeat ... See full document
11
Microglial neuroinflammation contributes to tau accumulation in chronic traumatic encephalopathy
... as tau induced neuroinflam- mation ...of chronic microglia activation might repre- sent an important therapeutic target for ...ptau pathology independent of ...mild traumatic brain injury ... See full document
9
Pathologic Thr175 tau phosphorylation in CTE and CTE with ALS
... pathologic tau aggregates contain aber- rantly phosphorylated tau with immunoreactivity to both pThr 175 tau and pThr 231 ...oligomeric tau) is consistent with a pivotal role for ... See full document
10
Tau pathology in the medial temporal lobe of athletes with chronic traumatic encephalopathy: a chronic effects of neurotrauma consortium study
... of cases with a history of contact-sport related ...and traumatic forces are more variable [35, 88, ...and tau pathology with these ...and tau pathologies during the progression of ... See full document
18
Clustering of tau-immunoreactive pathology in chronic traumatic encephalopathy
... Chronic traumatic encephalopathy (CTE) is a neurodegenerative disorder which may result from repetitive brain ...of tau-immunoreactive pathologies are present including neurofibrillary tangles ... See full document
25
Cortical degeneration in chronic traumatic encephalopathy and Alzheimer's disease neuropathologic change
... of tau-immunoreactive pathology is present in- cluding neurofibrillary tangles (NFT) and neuropil threads (NT) [3], dot-like grains (DLG) [5], and astrocytic tangles (AT) [2, ...and ... See full document
5
Scientific study of Unani formulations In the cases of osteoporosis
... the cases that became normal except in the cases where Osteopenia/osteoporosis continued and not responded with the ...these cases showing very slow response and not becoming ...above study ... See full document
10
A Biomechanical Assessment of Direct and Inertial Head Loading in Rugby Union
... The study identified that purely translational head motion could not cause concussion in the primates whereas rotational head motion could ...The study found that angular acceleration of the head in the ... See full document
183
Administration of electroconvulsive therapy for depression associated with deep brain stimulation in a patient with post traumatic Parkinson’s Disease: a case study
... This case report describes a patient with an atypical on- set of what is believed to be post-traumatic Parkinson ’ s syndrome. DBS proved beneficial for her worsening movement disorder similar to its established ... See full document
6
3D Visualization of the Temporal and Spatial Spread of Tau Pathology Reveals Extensive Sites of Tau Accumulation Associated with Neuronal Loss and Recognition Memory Deficit in Aged Tau Transgenic Mice
... abundant tau pathology seen in the LEC and Prh, and the significant neuronal loss in the EC of the oldest EC-Tau ...on tau mouse models with widespread expression of human mutant or wild-type ... See full document
22
Tau passive immunization inhibits not only tau but also Aβ pathology
... present study, we examined the dose-dependent effect of treat- ment with tau antibodies on pathology and cognitive performance and how long the beneficial effect could be sustained after ... See full document
16
Different tau species lead to heterogeneous tau pathology propagation and misfolding
... of tau using different species, 3R or 4R, mutant or wild-type ...of tau remains functional but tau pathology does not spread and stays in the vicinity of the initiation ...different tau ... See full document
12
Behavioral and Structural Effects of Single and Repeat Closed Head Injury
... In terms of behavioral changes, worse outcome seen after dou- ble injury compared with single injury supports the idea that there is cumulative injury after multiple impacts sustained within a close time period. We found ... See full document
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