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[PDF] Top 20 (25R) 5a Spiro­stane 3,12 dione

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(25R) 5a Spiro­stane 3,12 dione

(25R) 5a Spiro­stane 3,12 dione

... Steroid sapogenins are a class of important compounds, which present many significant bioactivities in platelet aggregation, arteriosclerosis and so on (Huang et al. , 2002). The hecogenin (25 R ... See full document

9

2a,5a Di­chloro 4 methyl 1 methyl­ene 2 phenyl 2a,5a di­hydro­cyclo­buta­[c]­pyrrole 3,5 dione

2a,5a Di­chloro 4 methyl 1 methyl­ene 2 phenyl 2a,5a di­hydro­cyclo­buta­[c]­pyrrole 3,5 dione

... O1 0.0493 (12) 0.0805 (17) 0.0320 (11) 0.0001 (12) 0.0193 (9) −0.0085 (11) O2 0.0337 (11) 0.0698 (16) 0.0558 (14) −0.0002 (11) −0.0074 (10) −0.0026 (12) N1 0.0267 (11) 0.0378 (13) 0.0436 (13) 0.0043 ... See full document

7

5,7 Di­bromo 1′ methyl 2′ (4 meth­oxy­benzoyl) 1H indole 3 spiro 2′ pyrrolidine 3′ spiro 3′′ 1H indole 2,2′′(3H,3′′H) dione methanol solvate

5,7 Di­bromo 1′ methyl 2′ (4 meth­oxy­benzoyl) 1H indole 3 spiro 2′ pyrrolidine 3′ spiro 3′′ 1H indole 2,2′′(3H,3′′H) dione methanol solvate

... C15 0.063 (3) 0.060 (2) 0.066 (2) −0.002 (2) −0.005 (2) −0.0241 (19) C16 0.041 (2) 0.0325 (16) 0.056 (2) 0.0025 (14) 0.0087 (16) 0.0093 (15) O17 0.0636 (18) 0.0478 (14) 0.0626 (17) 0.0105 (12) 0.0016 (13) ... See full document

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1,2,3,4 Tetra­hydro 4′ furfuryl 1′ methyl­naphthalene 2 spiro 3′ pyrrolidine 2′ spiro 1′′ acenaphthene 1,2′′ dione

1,2,3,4 Tetra­hydro 4′ furfuryl 1′ methyl­naphthalene 2 spiro 3′ pyrrolidine 2′ spiro 1′′ acenaphthene 1,2′′ dione

... C24 0.0660 (12) 0.0830 (14) 0.0706 (13) 0.0186 (11) 0.0380 (10) 0.0193 (11) C25 0.0521 (10) 0.0709 (12) 0.0650 (12) 0.0050 (9) 0.0216 (9) 0.0104 (9) C26 0.0633 (11) 0.0545 (10) 0.0545 (10) −0.0028 ... See full document

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4′ (4 Meth­oxy­benzoyl) 1′ methyl acenaphthene 1 spiro 2′ pyrrolidine 3′ spiro 3′′ 1H indole 2,2′′(1H,3′′H) dione hemihydrate

4′ (4 Meth­oxy­benzoyl) 1′ methyl acenaphthene 1 spiro 2′ pyrrolidine 3′ spiro 3′′ 1H indole 2,2′′(1H,3′′H) dione hemihydrate

... C17 0.0453 (16) 0.0371 (16) 0.0328 (14) 0.0003 (13) 0.0155 (13) −0.0004 (12) N18 0.0447 (14) 0.0347 (14) 0.0458 (14) 0.0039 (11) 0.0200 (11) −0.0029 (11) C19 0.0414 (16) 0.0385 (16) 0.0342 (15) −0.0013 (13) 0.0088 ... See full document

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4′ (4 Meth­oxy­phen­yl) 1′ methyl 9H fluorene 9 spiro 3′ pyrrolidine 2′ spiro 2′′ indan 1′′,3′′ dione

4′ (4 Meth­oxy­phen­yl) 1′ methyl 9H fluorene 9 spiro 3′ pyrrolidine 2′ spiro 2′′ indan 1′′,3′′ dione

... C16 0.0403 (10) 0.0611 (14) 0.0324 (11) 0.0133 (10) 0.0069 (8) −0.0036 (10) C17 0.0410 (10) 0.0471 (12) 0.0300 (10) 0.0103 (9) 0.0104 (8) 0.0011 (9) C18 0.0405 (10) 0.0372 (11) 0.0379 (12) 0.0017 (9) 0.0090 ... See full document

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1′ Methyl 4′ (2,4 di­chloro­phenyl) 1H indole 3 spiro 2′ pyrrolidine 3′ spiro 5′′ (thia­zolo­[3,2 b][1,2,4]­triazole) 2,6′′(3H,5′′H) dione

1′ Methyl 4′ (2,4 di­chloro­phenyl) 1H indole 3 spiro 2′ pyrrolidine 3′ spiro 5′′ (thia­zolo­[3,2 b][1,2,4]­triazole) 2,6′′(3H,5′′H) dione

... C16 0.050 (4) 0.055 (4) 0.049 (4) 0.021 (3) 0.016 (4) 0.013 (3) C17 0.064 (4) 0.076 (4) 0.057 (4) 0.037 (4) 0.033 (4) 0.023 (3) C18 0.045 (4) 0.076 (5) 0.079 (5) 0.015 (4) 0.035 (4) 0.029 (4) C19 ... See full document

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5′′ Benzyl­­idene 1′,1′′ di­methyl 4′ phenylacenapthene 2 spiro 2′ pyrrolidine 3′ spiro 3′′ piperidine 1,4′′ dione

5′′ Benzyl­­idene 1′,1′′ di­methyl 4′ phenylacenapthene 2 spiro 2′ pyrrolidine 3′ spiro 3′′ piperidine 1,4′′ dione

... C12 0.0588 (14) 0.0479 (15) 0.0539 (14) −0.0111 (12) 0.0153 (12) 0.0100 (11) C13 0.0402 (11) 0.0379 (13) 0.0476 (12) −0.0060 (9) 0.0167 (10) 0.0021 (10) C14 0.0333 (10) 0.0361 (13) 0.0570 (13) 0.0000 ... See full document

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3′′′ (2,6 Di­chloro­phenyl) 1′ methyl 4′,4′′′ di­phenyl 4′′′,5′′′ di­hydro indole 3 spiro 2′ pyrrolidine 3′ spiro 1′' cyclo­pentane 3′′ spiro 5′′′ [1,2]­oxazole 2(3H),2′′ dione

3′′′ (2,6 Di­chloro­phenyl) 1′ methyl 4′,4′′′ di­phenyl 4′′′,5′′′ di­hydro indole 3 spiro 2′ pyrrolidine 3′ spiro 1′' cyclo­pentane 3′′ spiro 5′′′ [1,2]­oxazole 2(3H),2′′ dione

... O2 0.0419 (12) 0.0492 (13) 0.0400 (13) −0.0025 (10) 0.0050 (10) 0.0164 (11) O3 0.0563 (14) 0.0354 (12) 0.0462 (14) −0.0029 (10) −0.0216 (11) 0.0057 (11) C1 0.0382 (17) 0.0304 (16) 0.0257 (17) −0.0032 (13) ... See full document

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1′ Methyl 4′,5 di­phenyl 5,6,7,8,9,10 hexa­hydro 1,3 cyclo­hepta­pyrimidino[2,3 b]thia­zole 2 spiro 3′ pyrrolidine 2′ spiro 3′′ 1H indole 2′′,3(2H,3′′H) dione

1′ Methyl 4′,5 di­phenyl 5,6,7,8,9,10 hexa­hydro 1,3 cyclo­hepta­pyrimidino[2,3 b]thia­zole 2 spiro 3′ pyrrolidine 2′ spiro 3′′ 1H indole 2′′,3(2H,3′′H) dione

... C18 0.13566 (14) 1.10980 (11) 0.30251 (11) 0.0359 (3) C19 0.19756 (14) 0.89089 (11) 0.31871 (10) 0.0328 (3) C20 0.06690 (14) 0.79198 (11) 0.13058 (10) 0.0332 (3) C21 −0.14170 (14) 0.63073 (12) ... See full document

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1′ Methyl 2′′ phenyl­cyclo­hexane 1 spiro 4′ [acenaphthene 1 spiro 2′ pyrrolidine 3′ spiro 4′′(5′′H) [1,3]­oxazole] 2,5′′ dione

1′ Methyl 2′′ phenyl­cyclo­hexane 1 spiro 4′ [acenaphthene 1 spiro 2′ pyrrolidine 3′ spiro 4′′(5′′H) [1,3]­oxazole] 2,5′′ dione

... C20 0.0370 (7) 0.0363 (6) 0.0356 (6) 0.0075 (5) 0.0093 (5) 0.0154 (5) O21 0.0410 (5) 0.0468 (5) 0.0458 (5) −0.0010 (4) 0.0040 (4) 0.0231 (4) C22 0.0419 (7) 0.0376 (6) 0.0369 (6) 0.0067 (6) 0.0060 (5) 0.0149 (5) O23 ... See full document

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4′ (4 Meth­oxy­phen­yl) 1′ methyl 5 di­phenyl 5,6,7,8,9,10 hexa­hydro 1,3 cyclo­hepta­pyrimidino[2,3 b]thia­zole 2 spiro 3′ pyrrolidine 2′ spiro 3′′ 1H indole 2′′,3(2H,3′′H) dione

4′ (4 Meth­oxy­phen­yl) 1′ methyl 5 di­phenyl 5,6,7,8,9,10 hexa­hydro 1,3 cyclo­hepta­pyrimidino[2,3 b]thia­zole 2 spiro 3′ pyrrolidine 2′ spiro 3′′ 1H indole 2′′,3(2H,3′′H) dione

... C3 0.0530 (8) 0.0479 (8) 0.0330 (7) −0.0133 (6) −0.0160 (6) −0.0095 (6) C4 0.0578 (9) 0.0501 (8) 0.0433 (8) −0.0109 (7) −0.0258 (7) −0.0056 (7) C5 0.0874 (13) 0.0471 (9) 0.0645 (11) −0.0206 (9) −0.0386 (10) 0.0022 (8) C6 ... See full document

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2′ (4 Bromo­benzoyl)­acenaphthene 1 spiro 3′ pyrrolizidine 1′ spiro 3′′ indole 2,2′′(1H,3′′H) dione monohydrate

2′ (4 Bromo­benzoyl)­acenaphthene 1 spiro 3′ pyrrolizidine 1′ spiro 3′′ indole 2,2′′(1H,3′′H) dione monohydrate

... C17 0.060 (3) 0.064 (2) 0.073 (3) 0.001 (2) 0.009 (2) −0.027 (2) C18 0.063 (3) 0.054 (2) 0.055 (2) −0.007 (2) −0.004 (2) −0.0096 (17) C19 0.057 (3) 0.0401 (19) 0.074 (3) −0.0010 (18) ... See full document

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5′′ Benzyl­­idene 1′ methyl 4′ phenyl­indole 3 spiro 2′ pyrrolidine 3′ spiro 3′′ piperidine 2(3H),4′′ dione

5′′ Benzyl­­idene 1′ methyl 4′ phenyl­indole 3 spiro 2′ pyrrolidine 3′ spiro 3′′ piperidine 2(3H),4′′ dione

... C16 0.0529 (12) 0.0614 (14) 0.0687 (15) −0.0084 (10) 0.0012 (11) 0.0082 (11) C17 0.0481 (12) 0.0900 (18) 0.0566 (13) 0.0012 (12) 0.0059 (10) 0.0177 (12) C18 0.0501 (12) 0.0885 (17) ... See full document

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7′ (4 Meth­oxy­phen­yl)chroman 3 spiro 6′ hexa­hydro 1H pyrrolo[1,2 c]thia­zole 5′ spiro 3′′ 1′′H indole 4,2′′(3′′H) dione

7′ (4 Meth­oxy­phen­yl)chroman 3 spiro 6′ hexa­hydro 1H pyrrolo[1,2 c]thia­zole 5′ spiro 3′′ 1′′H indole 4,2′′(3′′H) dione

... C27 0.0413 (10) 0.0365 (8) 0.0462 (9) −0.0013 (7) −0.0025 (7) 0.0010 (6) C15 0.0376 (10) 0.0613 (10) 0.0349 (8) −0.0002 (8) 0.0022 (6) −0.0014 (7) C11 0.0506 (11) 0.0477 (9) 0.0416 (8) 0.0015 (8) −0.0080 (7) −0.0102 (7) ... See full document

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1′ (4 Meth­oxy­benzoyl)­acenaphthene 1 spiro 3′ pyrrolizidine 2′ spiro 3′′ 1H indole 2,2′′(1H,3′′H) dione

1′ (4 Meth­oxy­benzoyl)­acenaphthene 1 spiro 3′ pyrrolizidine 2′ spiro 3′′ 1H indole 2,2′′(1H,3′′H) dione

... C15 0.050 (2) 0.057 (2) 0.033 (2) 0.0065 (19) 0.0038 (16) 0.0046 (17) C16 0.052 (2) 0.074 (3) 0.051 (2) −0.005 (2) −0.0069 (19) 0.012 (2) C17 0.060 (3) 0.078 (3) 0.070 (3) −0.005 (2) 0.000 (2) ... See full document

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(1′S) 4 (3,4 Di­chloro­phenyl) 1′ (3,5 di­methoxyphenyl) 1,2,3,4 tetra­hydro­naphthalene 2 spiro 2′ pyrrolizidine 3′ spiro 3′′ indoline 1,2′′ dione

(1′S) 4 (3,4 Di­chloro­phenyl) 1′ (3,5 di­methoxyphenyl) 1,2,3,4 tetra­hydro­naphthalene 2 spiro 2′ pyrrolizidine 3′ spiro 3′′ indoline 1,2′′ dione

... C32 0.0727 (13) 0.0442 (10) 0.0438 (9) −0.0215 (10) −0.0311 (9) 0.0014 (7) C33 0.0615 (11) 0.0319 (9) 0.0459 (9) −0.0118 (8) −0.0196 (8) 0.0000 (7) C34 0.0379 (8) 0.0332 (8) 0.0382 (8) −0.0084 (7) −0.0118 (6) 0.0045 (6) ... See full document

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1 Benzyl 4′,5′ di­phenyl­piperidine 3 spiro 3′ pyrrolidine 2′ spiro 3′′ indoline 4,2′′ dione

1 Benzyl 4′,5′ di­phenyl­piperidine 3 spiro 3′ pyrrolidine 2′ spiro 3′′ indoline 4,2′′ dione

... C58 0.073 (3) 0.122 (4) 0.067 (3) −0.028 (3) 0.010 (2) 0.013 (3) C59 0.054 (3) 0.119 (4) 0.078 (3) −0.017 (3) 0.002 (2) −0.003 (3) C60 0.053 (3) 0.105 ... See full document

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1′ Phenyl 6′ thia­cyclo­heptane 1 spiro 2′ perhydro­pyrrolizine 3′ spiro 3′′ indoline 2,2′′ dione

1′ Phenyl 6′ thia­cyclo­heptane 1 spiro 2′ perhydro­pyrrolizine 3′ spiro 3′′ indoline 2,2′′ dione

... C25 0.0442 (12) 0.0363 (11) 0.0350 (10) −0.0169 (9) −0.0070 (9) −0.0037 (9) N1 0.0371 (9) 0.0375 (9) 0.0259 (8) −0.0184 (7) −0.0141 (7) 0.0032 (7) N2 0.0430 (10) 0.0299 (8) 0.0372 (9) −0.0191 (7) −0.0074 (8) ... See full document

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1 Benzoylace­naphthyl­ene 1 spiro 3′ pyrrolizidine 2′ spiro 3′′ 1H indole 2,2′′(1H,3′′H) dione

1 Benzoylace­naphthyl­ene 1 spiro 3′ pyrrolizidine 2′ spiro 3′′ 1H indole 2,2′′(1H,3′′H) dione

... C16 0.0490 (12) 0.109 (2) 0.0596 (12) 0.0017 (12) 0.0059 (10) 0.0112 (12) C17 0.0645 (14) 0.0874 (17) 0.0755 (15) 0.0128 (12) 0.0221 (12) 0.0052 (13) C18 0.0769 (14) 0.0553 (11) ... See full document

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