[PDF] Top 20 Rab 5 Is Required for the Cellular Entry of Dengue and West Nile Viruses
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Rab 5 Is Required for the Cellular Entry of Dengue and West Nile Viruses
... and West Nile virus (WNV) are medically important flaviviruses that contain class II viral envelope ...their entry into host cells have not been fully delineated (2, 4, 7). Viruses with class ... See full document
5
Dengue and Zika Virus 5′ Untranslated Regions Harbor Internal Ribosomal Entry Site Functions
... RNA viruses. Dengue virus (DENV), a flavivirus, is the leading cause of serious arthropod-borne disease ...(YFV), West Nile fever virus (WNV), or Zika virus (ZIKV), control their translation by ... See full document
16
Complement Activation Is Required for Induction of a Protective Antibody Response against West Nile Virus Infection
... of dengue virus infection ...facilitating entry through CR3 (CD11b/CD18), complement activation was suggested to be pathogenic (8, ...or dengue virus infection (22, 25, 28, ...enveloped ... See full document
12
Chimeric Dengue 2 PDK-53/West Nile NY99 Viruses Retain the Phenotypic Attenuation Markers of the Candidate PDK-53 Vaccine Virus and Protect Mice against Lethal Challenge with West Nile Virus
... the 5 ⬘ end of the prM gene) and cWN-E (5 ⬘ -GAAGAGCAGAAC TCCGCCGGCTGCGAGAAACGTGAGAGCTATGG-3⬘; underlined NgoMIV site followed by complementary sequence near the 3 ⬘ end of the E gene of WN ...D2/WN ... See full document
11
West Nile Virus Discriminates between DC-SIGN and DC-SIGNR for Cellular Attachment and Infection
... of viruses, the defining characteristics of a cellular receptor have not been ...virus entry into a permissive ...support West Nile virus infection at some ...are required for ... See full document
12
Shell Vial culture Assay for the rapid diagnosis of Japanese encephalitis, West Nile and Dengue 2 viral encephalitis
... to 5–6 hours required for antigen detection by indirect immuno- fluorescent technique ...various viruses such as cytomegalovirus, Herpes Zoster, Mumps, Measles and respiratory syncytial virus ...the ... See full document
7
Identification of Five Interferon-Induced Cellular Proteins That Inhibit West Nile Virus and Dengue Virus Infections
... of cellular genes (9), only approx- imately a dozen ISGs have been experimentally demonstrated to instigate an antiviral state against selected viruses ... See full document
10
ISG15 facilitates cellular antiviral response to dengue and west nile virus infection in vitro
... Isg15 is upregulated upon DENV or WNV infection Mouse macrophage-like cell line RAW264.7 can be effi- ciently infected by DENV and WNV, and is an estab- lished in vitro model for the study of host innate immune response ... See full document
6
Epidemiological Analysis of Flavivirus Infections in Tamil Nadu with Specific Reference to Japanese Encephalitis, Dengue and West Nile Viruses. Development of a Novel Detection System.
... 4 viruses within the Baltimore classification scheme. Viruses in this class are positive sense, single stranded RNA viruses which replicate their genome through a partially double-stranded ... See full document
189
Protonation of Individual Histidine Residues Is Not Required for the pH-Dependent Entry of West Nile Virus: Evaluation of the “Histidine Switch” Hypothesis
... RNA viruses that cause a spec- trum of illnesses in humans ranging from fever to encephalitis and hemorrhagic disease ...and cellular membranes and pull them into the close apposition required to ... See full document
5
Peptide inhibitors of dengue virus and West Nile virus infectivity
... disparate viruses, including arenaviruses, coronaviruses, filoviruses, orthomyxovi- ruses, paramyxoviruses and retroviruses, encode similar proteins that together are classified as class I fusion pro- ... See full document
10
Cellular VPS4 Is Required for Efficient Entry and Egress of Budded Virions of Autographa californica Multiple Nucleopolyhedrovirus
... V irion budding from the cell plasma membrane is the final stage in the infection cycle of many enveloped viruses. Topologically, vi- rion budding appears identical to the formation of intraluminal ves- icles in ... See full document
14
Nucleic Acid Sequence Based Amplification Assays for Rapid Detection of West Nile and St Louis Encephalitis Viruses
... were 5⬘ labeled with the reporter dye 6-carboxyfluorescein (FAM) and labeled at the 3⬘ end with the quencher dye 6-carboxytetramethylrhodamine ...the 5⬘ end of the primer, and the forward primers contain a ... See full document
8
Mosquitoes infected with dengue viruses in Brazil
... report dengue virus surveillance in mosquitoes using a Flavivirus genus-specific RT-Hemi-Nested-PCR ...these viruses was identified as DENV-3 of genotype III, ... See full document
5
Factors associated with mosquito pool positivity and the characterization of the West Nile viruses found within Louisiana during 2007
... (NS1, NS2A, NS2B, NS3 NS4A, NS4B, and NS5) [5]. The NS3 gene plays an important role in the replication of the virus, encoding a protein with four functions: a serine protease, a nucleoside triphosphatase, an RNA ... See full document
8
VARIATION IN CLINICAL PRESENTATIONS OF DENGUE VIRUSES
... The required numbers of micro wells were removed from the foil sachet and were inserted into the strip ...were required for controls: positive control (P) in duplicate and negative control (N) in ... See full document
5
A Novel Agonist of the TRIF Pathway Induces a Cellular State Refractory to Replication of Zika, Chikungunya, and Dengue Viruses
... mRNA were synthesized and hybridized to Affymetrix Primeview microarrays as de- scribed in Materials and Methods. Probe sets exhibiting signals from AV-C or IFN-  treatments that were significantly above or below those ... See full document
22
CD4+ T-Cell Responses Are Required for Clearance of West Nile Virus from the Central Nervous System
... Because of the possible role of CD4 ⫹ T cells in priming protective adaptive immune responses against WNV, we ex- amined their function directly following infection. Using mice with genetic or acquired deficiencies in ... See full document
10
Immunoassay Targeting Nonstructural Protein 5 To Differentiate West Nile Virus Infection from Dengue and St Louis Encephalitis Virus Infections and from Flavivirus Vaccination
... NS5-based MIA differentiates WNV infection from DEN or SLE virus infections. The cross-reactivity of WNV NS5 and E protein with DEN infection was tested with 17 pairs of acute- and convalescent-phase sera from ... See full document
7
C elegans Rab GTPase 2 is required for the degradation of apoptotic cells
... not required for the initial uptake step of receptor-mediated endocytosis in developing oocytes, but is involved in the resecretion and trafficking of the yolk ...in rab-7(RNAi) animals and in the sand-1 ... See full document
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