[PDF] Top 20 A randomized controlled trial of daily sedation interruption in critically ill children
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A randomized controlled trial of daily sedation interruption in critically ill children
... she received a sedative infusion for active seizures, escalating sedative doses due to ongoing agitation, neu- romuscular blockers, had evidence of increased intracranial pressure or in cases of cardiorespiratory ... See full document
12
Daily interruption of sedation in critically ill children: study protocol for a randomized controlled trial
... For critically ill children, it is unknown if DSI is effect- ive, feasible and ...between children and adults have been ...In children, pro- pofol is contraindicated for prolonged ... See full document
6
Optimizing antibiotic prescribing for acutely ill children in primary care (ERNIE2 study protocol, part B): a cluster randomized, factorial controlled trial evaluating the effect of a point-of-care C-reactive protein test and a brief intervention combined with written safety net advice
... paediatricians, at UZ Leuven, under supervision of Prof. Christel Van Geet and Prof. Dominique Bullens, at AZ Turnhout under supervision of Dr. Luc Pattyn, at Jessa Hasselt under supervision of Dr. Marc Raes, at UZ Gent ... See full document
9
Enteral versus intravenous approach for the sedation of critically ill patients: a randomized and controlled trial
... GM is the principal investigator of the study and responsible for the conception, protocol design, and organization of financial support. GI applied for and received financial support from the Regione Lombardia to start ... See full document
10
Randomized trial comparing daily interruption of sedation and nursing implemented sedation algorithm in medical intensive care unit patients
... in critically ill patients with alco- hol use disorders ...achieve sedation levels similar to patients without these disorders ...their sedation interrupted in the ABC ...ABC trial, ... See full document
9
Nebulized heparin is associated with fewer days of mechanical ventilation in critically ill patients: a randomized controlled trial
... Demographic data were collected on study entry, and ventilation parameters, clinical and radiological data, sputum character, medication usage, and adverse events, including blood-stained sputum or frank blood in spu- ... See full document
10
Sedation and renal impairment in critically ill patients: a post hoc analysis of a randomized trial
... of sedation because of increased intracranial pressure or undergoing thera- peutic ...without sedation (coma hepaticum or neurological ...were randomized in two groups: 70 patients in the awake ... See full document
6
A randomized controlled proof of concept trial of early sedation management using Responsiveness Index monitoring in mechanically ventilated critically ill patients
... intravenous sedation with a hypnotic agent by continuous ...the trial; had status epilepticus; had confirmed meningi- tis or encephalitis, or had a known chronic neurological disease interfering with normal ... See full document
10
Intensive care sedation: the past, present and the future
... when sedation is managed with a sedation protocol that targets light ...multicenter randomized trial comparing PS with combined PS plus DSI in 423 critically ill mechanically ... See full document
7
A randomized controlled trial of tea tree oil (5%) body wash versus standard body wash to prevent colonization with methicillin resistant Staphylococcus aureus (MRSA) in critically ill adults: research protocol
... a randomized controlled trial of 110 patients who received 5% topical TTO for five days in a study of MRSA decolonization, no participants experienced adverse effects and no premature discontinuation ... See full document
9
Decreasing Delirium through Music (DDM) in critically ill, mechanically ventilated patients in the intensive care unit: study protocol for a pilot randomized controlled trial
... be randomized to one of three arms (20 participants per arm): (1) personalized music, (2) non-personalized relaxing music, or (3) ...the trial design (recruitment, adherence, participant retention, design ... See full document
8
Long term psychological effects of a no sedation protocol in critically ill patients
... of sedation has ...nurse-implemented sedation protocol, including only bolus doses of sedation, could reduce the time patients received mechanical ...a daily interrup- tion of sedatives could ... See full document
8
Dexmedetomidine Based Sedation for Post-surgery Critically Ill Adults: A Meta-analysis of Randomized Controlled Trials
... optimal sedation regimen is essential for treatment of post-surgery patients in intensive care unit ...facilitate daily ICU procedure, reduce anxiety, improve tolerance of mechanical ventilation, shorten ... See full document
12
Non sedation versus sedation with a daily wake up trial in critically ill patients recieving mechanical ventilation effects on long term cognitive function: Study protocol for a randomized controlled trial, a substudy of the NONSEDA trial
... the patients could spoil this blinding by revealing their randomization, but experience tells us that most patients are unaware as to which of the two groups they have been in. Memory can be severely affected by multiple ... See full document
8
Daily sedative interruption versus intermittent sedation in mechanically ventilated critically ill patients: a randomized trial
... no-sedation trial, the awake patients needed an extra person to take care of them ...this sedation strategy in a lower staff ...lighter sedation was not associated with a number of adverse ... See full document
12
Non sedation versus sedation with a daily wake up trial in critically ill patients receiving mechanical ventilation—effects on physical function: study protocol for a randomized controlled trial: a substudy of the NONSEDA trial
... Poulsen and colleagues in 2013 published results on biomechanical function in ICU survivors (males, aged 50–75 years, 12 months after ICU discharge) compared to healthy, age- and sex-matched controls [47]. Their study is ... See full document
10
Non sedation versus sedation with a daily wake up trial in critically ill patients receiving mechanical ventilation (NONSEDA Trial): study protocol for a randomised controlled trial
... a trial from 2000, Kress et al. randomised 128 critically ill patients receiving mechanical ventilation to continuous intravenous sedation with or without a daily wake-up trial, ... See full document
11
Validity of the Richmond Agitation-Sedation Scale (RASS) in critically ill children
... Pediatric Sedation-Agitation Scale (P- SAS), is being developed based on the Sedation Agita- tion Scale for ...in children, but this scale only measures sedation and is therefore not useful in ... See full document
6
Argatroban versus Lepirudin in critically ill patients (ALicia): a randomized controlled trial
... the trial as initially planned would not have had a significant effect on our ...of critically ill surgical patients with continuous renal replacement ...of critically ill pa- tients ... See full document
8
Current practices and barriers impairing physicians’ and nurses’ adherence to analgo sedation recommendations in the intensive care unit a national survey
... where sedation is used for reasons other than agitation (concomitant management with neuromuscu- lar blocking agents, seizures and refractory intracranial ... See full document
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