[PDF] Top 20 Relationship of the K-ras/c-mos Expression Patterns With Angiogenesis in Non-Small Cell Lung Carcinomas
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Relationship of the K-ras/c-mos Expression Patterns With Angiogenesis in Non-Small Cell Lung Carcinomas
... the K-ras(No)/ c-mos(P) pattern is related to vessel regression, which acts in a particular stage of tumor develop- ment as a negative selective-pressure mechanism, by creating a hypoxic ... See full document
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Low Levels of p27 in Association With Deregulated p53-pRb Protein Status Enhance Tumor Proliferation and Chromosomal Instability in Non-Small Cell Lung Carcinomas
... well-differentiated lung AdCs, immunostaining patterns of p27 and Ki-67 are similar, with expression mostly occurring in the periphery of tumor nodules, in cells possessing an increased proliferative ... See full document
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Analysis of microRNA (miRNA) expression profiles reveals 11 key biomarkers associated with non small cell lung cancer
... affect expression of multiple target genes; on the other hand, a specific mRNA may be regulated by cer- tain different ...programmed cell death protein 4 (PDCD4) [34] and PTEN ...regulating ... See full document
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Determination of SGK1 mRNA in non-small cell lung cancer samples underlines high expression in squamous cell carcinomas
... mRNA expression mainly in the squamous cell subtype of NSCLC may pave the way for specific targeted therapies in this NSCLC ...squamous cell carcinoma appears neglected as far as targeted molecular ... See full document
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A comparison of Direct sequencing, Pyrosequencing, High resolution melting analysis, TheraScreen DxS, and the K-ras StripAssay for detecting KRAS mutations in non small cell lung carcinomas
... At present, identifying targeted anticancer treatment suitable for a given patient requires the availability of ac- curate diagnostics. Diagnostic techniques therefore have a significant impact on patients’ survival and ... See full document
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Original Article Relationship of Fas, FasL, p53 and bcl-2 expression in human non-small cell lung carcinomas
... Fas expression is an integral part of the process of lung tumori- genesis, by allowing lung tumor cells to escape attack by activated cytotoxic T cells which are frequently present in ... See full document
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Restoration of mutant K-Ras repressed miR-199b inhibits K-Ras mutant non-small cell lung cancer progression
... by K-Ras (G12D) overexpression in both NSCLC cell lines compared to the respective control ...NSCLC cell line analysis results showed that miR-199b was dramatically decreased in ... See full document
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TIPE2 suppresses angiogenesis and non-small cell lung cancer (NSCLC) invasiveness via inhibiting Rac1 activation and VEGF expression
... The expression conditions and effects of TIPE2 in some tumors were explored and discussed preliminarily [9, ...the Ras superfamily of small GTPases, which is involved in a variety of important ... See full document
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The effect of HER2 expression on cisplatin-based chemotherapy in advanced non-small cell lung cancer patients
... in lung cancer patients, is a member of the EGFR family. Also known as c-erbB-2, HER2 is encoded by a gene located in the chromosomal region ...in cell proliferation, angiogen- esis, and metastatic ... See full document
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CD10/NEP in non small cell lung carcinomas Relationship to cellular proliferation
... proliferating cell nuclear antigen ...CD10/NEP expression when the highest percentage of cells were actively dividing; in addition, these cells grew more rapidly when cell surface CD10/NEP was ... See full document
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Genome-wide DNA methylation profiling of non-small cell lung carcinomas
... enable non-invasive diagnosis and early detection of the disease, and potentially allow histological classifi- ...paired lung tissues, and comprehensive lists of DMRs and associated genes in ... See full document
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FDG PET in the evaluation of response to nivolumab in recurrent non small cell lung cancer
... Case presentation: We report on a 75-year-old man on nivolumab treatment for metastatic non-small cell lung cancer. He had undergone right lower lobectomy for lung adenocarcinoma in the ... See full document
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<p>Knockdown of CHPF suppresses cell progression of non-small-cell lung cancer</p>
... estimates, lung cancer constitutes 13% of total cancer incidence and was responsible for ...most lung cancers are non- small-cell lung cancer ...high expression of ... See full document
9
Prognosis of ampullary cancer based on immunohistochemical type and expression of osteopontin
... advanced non-small cell lung cancer [15], laryngeal and hypopharyngeal carcinomas [16], hepatocellular carcinoma [17], colorectal cancer [18], idiopathic pulmonary hypertension [19], ... See full document
7
The roles of metallothioneins in carcinogenesis
... 120], small cell lung cancer [121], non-small cell lung cancer [122], renal cell carcinoma [123, 124], melanoma [24, 125], bladder cancer [23, 126], oral squamous ... See full document
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Clinicopathological significance of fascin-1 expression in patients with non-small cell lung cancer
... Protein lysis buffer was applied to extract the protein in tis- sues. The bicinchoninic acid assay method was used to mea- sure protein concentrations, collecting protein at 80 μ g/hole to conduct 8% sodium dodecyl ... See full document
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Prognostic role of HSF1 overexpression in solid tumors: a pooled analysis of 3,159 patients
... Nevertheless, this meta-analysis has some limitations. First, given the limited number of included studies for a comprehensive analysis, the pooled conclusions may be less powerful and should be interpreted with caution, ... See full document
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Improved diagnostics targeting c-MET in non-small cell lung cancer: expression, amplification and activation?
... 222 lung tumor specimens from patients with NSCLC were obtained from the Biomaterial Bank North after resection from the surgical department of Lungen- Clinic Grosshansdorf (Table 1), including 110 cases of ... See full document
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Impact of chemotherapy in the prognosis of non-small-cell lung cancer patients with severe to very severe COPD
... stage, stage III dominated in the chemotherapy group (22/45), while stage IV dominated in the non-chemotherapy group (11/24), a difference that was also not statistically different. In summary, no statistically ... See full document
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<p>Anlotinib Suppresses Colorectal Cancer Proliferation and Angiogenesis via Inhibition of AKT/ERK Signaling Cascade</p>
... (50X). Cell cycle distribution was analyzed using a fl ow cytometer with PI/RNase staining buffer (BD Biosciences, CA, ...USA). Cell apoptosis assay was performed using FITC Annexin V Apoptosis Detection ... See full document
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