[PDF] Top 20 Role of Autophagy in HIV-1 Matrix Protein p17-Driven Lymphangiogenesis
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Role of Autophagy in HIV-1 Matrix Protein p17-Driven Lymphangiogenesis
... that p17 and its variant proteins may play a key role in producing a microenvironment that fosters lymphoma growth and ...targeting p17 and its B-cell growth-promoting ...neutralizing p17 ... See full document
17
A role of autophagy in PTP4A3 driven cancer progression
... accumulate, autophagy flux is enhanced and consequently becomes degraded by autophagy, thereby eventually returning autophagy activity to a homeostatic functional ...only autophagy- regulated ... See full document
14
The role for autophagy in cancer
... the role of autophagy only in tumors and not with direct comparison to autophagy deficiency in normal tis- ...know autophagy is important for some normal tis- sues, a critical question is ... See full document
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The protective role of autophagy in experimental osteoarthritis, and the therapeutic effects of Torin 1 on osteoarthritis by activating autophagy
... exact role of autophagy in OA and investigate effective therapeutic drugs to inhibit the pathological progression of OA, we add the treatment of Torin 1 and 3-MA in celluar OA model and rabbit OA ... See full document
8
Regulation of Aβ pathology by beclin 1: a protective role for autophagy?
... Beclin 1 is an important multifunc- tional protein that also plays an impor- tant role in autophagy (11, ...the autophagy pathway in ...beclin 1 activity may be a therapeutic ... See full document
5
Dual role of autophagy in HIV-1 replication and pathogenesis
... between autophagy and HIV-1 ...of HIV-1 to promote auto- phagy in bystander CD4+ T cells renders those cells more susceptible to HIV-1 ...of HIV-1 on ... See full document
13
The autophagy protein ATG9A promotes HIV 1 infectivity
... the HIV-1-producing cells for optimal infectivity of the viral ...its role in the promotion of viral infectivity turned out to be unrelated phenomena, ...enhanced HIV-1 ...in ... See full document
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HIV-1 Antisense Protein of Different Clades Induces Autophagy and Associates with the Autophagy Factor p62
... transcript-encoded HIV-1 antisense protein (ASP) was recently reinforced by in silico analyses providing evidence for recent appearance of this gene in the viral ...induced autophagy, po- ... See full document
20
Detection of the HIV-1 Minus-Strand-Encoded Antisense Protein and Its Association with Autophagy
... of autophagy at an early step increased the number of ASP- positive cells but led to a loss in the number of ASP ...upon autophagy inhibition. Finally, we show that HIV-1 replication in U937 ... See full document
17
The role of HIV Tat protein in HIV related cardiovascular diseases
... between autophagy and HIV-mediated enhancement of pro- liferation of apoptosis-resistant pulmonary endothe- lial ...both autophagy and apoptosis. However, chronic increase in autophagy reduces ... See full document
7
Proton Channel Activity of Influenza A Virus Matrix Protein 2 Contributes to Autophagy Arrest
... arrest autophagy, as evidenced by autophagosome accumulation in infected ...virus matrix protein 2 ...a role in blocking the fusion of autophagosomes with lysosomes, which might be a key ... See full document
8
HIV-1 and Morphine Regulation of Autophagy in Microglia: Limited Interactions in the Context of HIV-1 Infection and Opioid Abuse
... that autophagy influences the viral replication cycle and silencing of autophagic factors results in the long-term inhibition of HIV-1 replication ...CCR5-tropic HIV-1 strains (26). ... See full document
12
Inhibition of HIV 1 replication with stable RNAi mediated knockdown of autophagy factors
... of autophagy factors leads to inhibition of HIV-1 ...13 autophagy fac- tors (ATGs) were tested and inhibition of virus replica- tion was scored for 7 ...and autophagy tests, which ... See full document
11
Inhibition of Early and Late Events of the HIV-1 Replication Cycle by Cytoplasmic Fab Intrabodies against the Matrix Protein, p17
... Inhibition of HIV-1 Proviral Gene Expression of CD4+ Jurkat T Cells Stably Expressing Cytoplasmic Anti-MA Fab3H7 Intrabodies. The ability of cytoplasmic Fab3H7 intrabodies to inhibit HIV[r] ... See full document
15
HIV-1 matrix protein p17 and its variants promote human triple negative breast cancer cell aggressiveness
... Data presented in this study show that both refp17 and some vp17s isolated from plasma of HIV + patients with NHL strongly enhance MDA-MB 231 cell migra- tion and invasiveness. The most aggressive breast cancer ... See full document
9
Structure-function studies of the human immunodeficiency virus type 1 matrix protein, p17.
... of p17 have identified both single amino acids and regions of the protein that appear essential for p17 function (reviewed in reference ...of p17, rather than as a result of the substitution ... See full document
10
Characterization of human immunodeficiency virus type 1 p17 matrix protein motifs associated with mother-to-child transmission.
... type 1 (HIV-1), we used a direct solid-phase sequencing method to sequence the p17 matrix protein-encoding regions of viral isolates from 12 HIV-1-infected ... See full document
10
Detection of a Trimeric Human Immunodeficiency Virus Type 1 Gag Intermediate Is Dependent on Sequences in the Matrix Protein, p17
... key role for this helix in the assembly ...key role in stabilizing the trimeric interface. This implies a role for the MA trimer in virus ...trimerization driven by the MA domain is an ... See full document
5
Membrane Binding of HIV-1 Matrix Protein: Dependence on Bilayer Composition and Protein Lipidation
... The protein load at saturation increased for both proteins, and in particular the membrane load of ⫹myrMA almost doubled in the presence of cholesterol in DOPC/DOPS ...the protein through FIG 2 Comparison ... See full document
12
The crucial role of macrophages in lymphangiogenesis
... is driven by incorporation of progenitor cells or by local endothelial cell ...support lymphangiogenesis in 2 different ways, either by transdiffer- entiating and directly incorporating into the endothelial ... See full document
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