[PDF] Top 20 Role of non-coding RNAs in maintaining primary airway smooth muscle cells
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Role of non-coding RNAs in maintaining primary airway smooth muscle cells
... critical role in proper axon guid- ance and maintenance and is expressed in non-small cell lung cancer [21] and WDFY4, a protein with unknown function but is predominantly expressed in primary and ... See full document
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The functional role of long non-coding RNAs and epigenetics
... important role in cell fate decision ...The role of non-coding RNAs in chromatin formation has also been ob- served in plants ...a non-coding antisense transcript to the ... See full document
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Emerging role of long non-coding RNAs in cisplatin resistance
... of enzymes involved in GSH synthesis and metabolism par- ticipates in the process of cisplatin resistance. The lncRNA H19 was overexpressed in ovarian cancer tissues and cor- related with cancer recurrence, whereas H19 ... See full document
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The Role of Long Non-Coding RNAs in Ovarian Cancer
... cancer cells with distinct metastatic potentials [9] ...metastatic cells, compared with the parental cells, respectively, which shows a possible role for lncRNAs in epithelial ovarian cancer ... See full document
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Role of Long Non coding RNAs in Sculpting Neurons
... specialized cells of the brain involved in rapidly transmitting signals- electrical and chemical - from cell to ...neighboring cells, integrate these inputs to determine if they will be transmitted further ... See full document
8
RNA: a possible contributor to the 'missing heritability’
... the non-coding RNA might be another player involved in this ...whether non coding RNAs are also implicated in pater- nal epigenetic ...a role in paternal epigenetic ... See full document
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Long non-coding RNAs in the regulation of myeloid cells
... NB4 cells, the up-regulation of HOTAIRM1 is based on the expression of myeloid cell development fac- tors targeted by RA ...a role in myelopoiesis through modula- tion of gene expression in the HOXA cluster ... See full document
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Epigenetic modifications in essential hypertension
... Non-coding RNAs (ncRNA) are implicated in several epigenetic processes, notably small RNAs that can influence histone modifications and cytosine methylation which are connected with gene ... See full document
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Databases and resources for human small non-coding RNAs
... Recent advances in high-throughput sequencing have facilitated the genome-wide studies of small non-coding RNAs (sRNAs). Numerous studies have highlighted the role of various classes of sRNAs ... See full document
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Construction of asthma related competing endogenous RNA network revealed novel long non-coding RNAs and potential new drugs
... anti-inflammatory role in autoimmune neuroinflamma- tion ...epithelial cells (BEC), the expression of miR-19a was upregulated in severe asthmatics, which enhanced cell proliferation of BEC by targeting ... See full document
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Non coding RNAs in muscle differentiation and musculoskeletal disease
... defined role in the control of the progression of nascent mesoderm toward the cardiac ...stem cells (ESCs) toward a cardiac fate, suggesting a possible role in cardiac tissue regeneration after ... See full document
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PM2.5 promotes human bronchial smooth muscle cell migration via the sonic hedgehog signaling pathway
... In this study, we investigated the pro-apoptotic and proliferative effects of PM2.5 on HBSMCs. Our results indicated that a low dose of TAPM2.5 (15 μg/ml) or WSPM2.5 (3 μg/ml) did not induce significant prolifera- tion ... See full document
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No evidence for altered intracellular calcium-handling in airway smooth muscle cells from human subjects with asthma
... Apparatus). Cells were maintained at 37°C and perfused at a rate of ...a non-linear two phase exponential curve fit with a recovery rate K (s −1 ) derived for each ...using cells loaded with Fluo-4 ... See full document
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Airway smooth muscle NOX4 is upregulated and modulates ROS generation in COPD
... Increased airway smooth muscle (ASM) mass is a feature of small airway disease and is related to airflow obstruction ...what role, if any, ... See full document
5
Human airway smooth muscle cell proliferation from asthmatics is negatively regulated by semaphorin3A
... target cells [17, ...in primary HASMC from 3 different healthy and asthmatic ...HASMC cells from healthy donors (Figure 1D) or asthmatics (data not ...surrounding airway epithelium of healthy ... See full document
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DUSP10 Negatively Regulates the Inflammatory Response to Rhinovirus through Interleukin-1β Signaling
... epithelial cells to RV ...in primary bronchial epithelial cells, and one of them, DUSP10, was down- regulated by RV ...a role for the protein in negatively regulating inflammatory cytokine pro- ... See full document
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Plk1 regulates MEK1/2 and proliferation in airway smooth muscle cells
... The physiological properties of Plk1 in the early stage of the growth factor response have not been investi- gated. In the present study, Plk1 underwent phosphor- ylation at Thr-210 in quiescent smooth ... See full document
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Distinct Effects of Ca2+ Sparks on Cerebral Artery and Airway Smooth Muscle Cell Tone in Mice and Humans
... ASM: airway smooth muscle; ASMCs: airway smooth muscle cells; CASMCs: cerebral artery smooth muscle cells; Ca 2+ sparks: spontaneous, transient local Ca 2+ elevations; RyRs: ry[r] ... See full document
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Signal transduction around thymic stromal lymphopoietin (TSLP) in atopic asthma
... epithelial cells with different allergens induces the expression of TSLP mRNA (Borowski et ...in airway epithelial cells, and that the response is mediated by a pathway involving TLR3, NFκB and and ... See full document
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Bronchial thermoplasty and the role of airway smooth muscle: are we on the right direction?
... On the basis of current knowledge, the assumption is that bronchial thermoplasty can denature and destroy ASM allowing the reduction of bronchospasm, resulting in improved control of the symptoms of severe asthma. Early ... See full document
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