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[PDF] Top 20 Role of downregulated miR-133a-3p expression in bladder cancer: a bioinformatics study

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Role of downregulated miR-133a-3p expression in bladder cancer: a bioinformatics study

Role of downregulated miR-133a-3p expression in bladder cancer: a bioinformatics study

... A total of 14 online prediction software, miRWalk, Microt4, miRanda, mirbridge, miRDB, miRMap, miRNAMap, Pictar2, PITA, RNA22, RNAhybrid, Targetscan, mirTarbase and PolymiRTS, were employed to collect the target genes of ... See full document

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Original Article Urinary microRNAs as potential biomarkers for differentiating the “atypical urothelial cells” category of the Paris system for reporting urine cytology

Original Article Urinary microRNAs as potential biomarkers for differentiating the “atypical urothelial cells” category of the Paris system for reporting urine cytology

... consistently downregulated miRNA in this meta-analysis was miR-145, which was found in five ...miRNA expression profiling studies that have shown that miR-145 is reduced in prostate, ... See full document

11

MicroRNA 124 3p inhibits cell migration and invasion in bladder cancer cells by targeting ROCK1

MicroRNA 124 3p inhibits cell migration and invasion in bladder cancer cells by targeting ROCK1

... this study, we demonstrated the pathologically down-regulation of miR-124-3p in both bladder cancer specimens and cell ...of miR- 124-3p not only repressed cell motility ... See full document

13

Downregulation of miR-133a-3p promotes prostate cancer bone metastasis via activating PI3K/AKT signaling

Downregulation of miR-133a-3p promotes prostate cancer bone metastasis via activating PI3K/AKT signaling

... aberrant expression of miRNAs constitutes a compelling component in epigenome. miR-27b has been reported to decreased in diffuse large B-cell lymphoma ...Forced expression of miR-27b ... See full document

16

Original Article Role of miR-1 and its potential regulation of signaling pathways in bladder cancer: a comprehensive investigation based on TCGA, GEO, ArrayExpress, and bioinformatics analysis

Original Article Role of miR-1 and its potential regulation of signaling pathways in bladder cancer: a comprehensive investigation based on TCGA, GEO, ArrayExpress, and bioinformatics analysis

... as miR-1, miR-133a, miR-133b, and miR-206, are abnormally expre- ssed in certain malignancies and that they play vital roles in tumor initiation, progression, and ...of miR-1 in ... See full document

14

Circ_ZNF124 promotes non-small cell lung cancer progression by abolishing miR-337-3p mediated downregulation of JAK2/STAT3 signaling pathway

Circ_ZNF124 promotes non-small cell lung cancer progression by abolishing miR-337-3p mediated downregulation of JAK2/STAT3 signaling pathway

... many cancer progression and metasta- sis [5, 20, ...of miR-337-3p. Indeed, when miR-337-3p mimic was transfected into A549 and H1975, JAK2 protein level was greatly reduced, luciferase ... See full document

13

<p>CircRNA SMARCC1 Sponges MiR-140-3p to Regulate Cell Progression in Colorectal Cancer</p>

<p>CircRNA SMARCC1 Sponges MiR-140-3p to Regulate Cell Progression in Colorectal Cancer</p>

... critical role in CRC carcinogenesis, providing novel insights into the pathogenesis of ...this study, we found that circSMARCC1 level was high in the clinical CRC tissues and four cell lines (SW620, HCT116, ... See full document

12

&lt;p&gt;LncRNA LEF1-AS1 Promotes Ovarian Cancer Development Through Interacting with miR-1285-3p&lt;/p&gt;

<p>LncRNA LEF1-AS1 Promotes Ovarian Cancer Development Through Interacting with miR-1285-3p</p>

... the role of miR-1285-3p in ovarian cancer still remains ...indicated miR-1285-3p may be a tumor suppressor. For example, miR-1285-3p could target JUN to inhibit ... See full document

8

miR 3156 3p is downregulated in HPV positive cervical cancer and performs as a tumor suppressive miRNA

miR 3156 3p is downregulated in HPV positive cervical cancer and performs as a tumor suppressive miRNA

... To study the functional role of miR-3156-3p in CC, we modulated miR-3156-3p expression in CC in vitro using miRNA mimics and an ...of miR-3156-3p ... See full document

13

Loss of has-miR-337-3p expression is associated with lymph node metastasis of human gastric cancer

Loss of has-miR-337-3p expression is associated with lymph node metastasis of human gastric cancer

... miRNA expression plays a role in tumor de- velopment and progression, such as tumor cell prolifera- tion, invasion, and metastasis [8]; in addition, certain miRNAs also can predict the prognosis of various ... See full document

9

Original Article Genetic alteration and prospective signaling pathways of miR-517a-3p in bladder cancer: a study based on miRNA sequencing data and bioinformatics methods

Original Article Genetic alteration and prospective signaling pathways of miR-517a-3p in bladder cancer: a study based on miRNA sequencing data and bioinformatics methods

... of miR-517a-3p in diseases, only several studies have reported its possible target ...of miR-517a-3p both in colorectal can- cer [22] and lung cancer [23], and miR-517a-3p ... See full document

15

Novel role of miR-133a-3p in repressing gastric cancer growth and metastasis via blocking autophagy-mediated glutaminolysis

Novel role of miR-133a-3p in repressing gastric cancer growth and metastasis via blocking autophagy-mediated glutaminolysis

... miRNAs, miR-133a-3p is reported to be a tumor suppressor in numerous cancer types including pros- tate cancer [32], gastric cancer [33], and bladder cancer [34] ... See full document

22

Original Article Expression of miR-625-3p in colon cancer and its correlation with prognosis

Original Article Expression of miR-625-3p in colon cancer and its correlation with prognosis

... of miR-625-3p in peripheral blood of patients with colon cancer was higher than that of normal subjects, suggesting that miR-625- 3p may be involved in the occurrence and development of ... See full document

8

TRIM11, a direct target of miR-24-3p, promotes cell proliferation and inhibits apoptosis in colon cancer

TRIM11, a direct target of miR-24-3p, promotes cell proliferation and inhibits apoptosis in colon cancer

... gene expression by binding to the 3’-untranslated region (3’-UTR) of specific mRNAs and targeting them for degradation or translational repression ...microRNAs, miR-24-3p has been shown to act as a ... See full document

11

&lt;p&gt;High miR-454-3p expression predicts poor prognosis in hepatocellular carcinoma&lt;/p&gt;

<p>High miR-454-3p expression predicts poor prognosis in hepatocellular carcinoma</p>

... present study has demonstrated a universal fact that miR-454-3p may be a signi fi cant independent predictor of poor prognosis in HCC patients through TCGA database ...of miR-454-3p ... See full document

8

Original Article MicroRNA-129-3p functions as a tumor suppressor in serous ovarian cancer by targeting BZW1

Original Article MicroRNA-129-3p functions as a tumor suppressor in serous ovarian cancer by targeting BZW1

... previous study, we identified the deregulated miRNAs in serous ovarian cancer via a microarray and quantita- tive PCR (qPCR), and found that miR-129-1-3p and miR-129-2-3p levels ... See full document

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Effect of miR-27a-3p on Proliferation and Migration in Non-small Cell Lung Cancer Cells

Effect of miR-27a-3p on Proliferation and Migration in Non-small Cell Lung Cancer Cells

... pancreatic cancer, breast cancer, ovarian cancer, esophageal cancer, renal cell carcinoma, lung cancer and glioma, and was closely related to the biological behavior of cancer ... See full document

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MiR-27a-3p functions as an oncogene in gastric cancer by targeting BTG2

MiR-27a-3p functions as an oncogene in gastric cancer by targeting BTG2

... BTG2 expression and C-myc expression in 20 paired clinical GC samples by Real- time PCR analysis (Figure ...the expression of C-myc by western blot ...the expression of C-myc (Figure ...the ... See full document

12

Original Article Effects of miR-545-3p expression in esophageal cancer tissues on proliferation and apoptosis of esophageal cancer cells

Original Article Effects of miR-545-3p expression in esophageal cancer tissues on proliferation and apoptosis of esophageal cancer cells

... that miR- NAs are closely related to biological behaviors of tumor cells, including proliferation and inva- sion [8, ...years, miR-545-3p might be a new marker for the treatment and prognosis of ... See full document

7

Original Article miR-22-3p suppresses cell proliferation by regulating SP1 in hepatocellular carcinoma

Original Article miR-22-3p suppresses cell proliferation by regulating SP1 in hepatocellular carcinoma

... gene expression was used to determine miR- NAs expression ...for miR-22-3p and u6 sn-RNA were 50-AAGCTGCCAGTTGAAGAACTGTA-30 and Uni- versal Primer (TIANGEN BIOTECH, BEIJING, ... See full document

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