[PDF] Top 20 The Role of the Endocannabinoid System in the Gynaecological Malignancy

... the endocannabinoid system may play a decisive role in the development and progression of gynaecological ...The endocannabinoid system activity is very complex, involving ... See full document

... the endocannabinoid system in the neurobiology of mood ...(i.e., endocannabinoid reuptake inhibition or reduced enzymat- ic degradation) stimulation of cannabinoid CB1 receptors exerts an ... See full document

... the endocannabinoid system (ECS) as a potent coordinator of AT ...The role of ECS on modulating these important metabolic processes empha- sizes the potential of the ECS to reduce the intensity ... See full document

... their role in the patho- genesis of cancer ...the endocannabinoid system is able to initiate apoptosis and autophagy, in- duce cell cycle arrest, mount inflammatory responses against malignant cells, ... See full document

... extensive system with relative basic levels of each component that is modulated by different and concurring molecular mechanisms [8, ...general role for eCBs and congeners in the preservation of metabolic ... See full document

... Priorities for Future Studies The ECS is increasingly incriminated in several pathophysiological aspects associated with chronic liver disease progression (Figure). Steatogenic and profibrogenic properties of CB1 ... See full document

... 1.3 Role of the Endocannabinoid System in the development of au- tistic behavior in the Fmr1- KO mouse The ECS is an important neuromodulatory system that became known in 1964 by the discovery ... See full document

... protective role against atherosclerosis, in addition to its insulin sensitizer effect ...the endocannabinoid system using a chronic oral treatment with rimonabant simultaneously reduces body weight ... See full document

... in both early and progressive phases of MS. Alternatively, enhancement of the endogenous levels of eCBs by inhibiting FAAH and/or MAGL appears an opportunity to be tested in MS patients, because it is expected to control ... See full document

... system’s role in food intake and glucose and lipid ...alter endocannabinoid system activity is a pertinent area of research due to public health messages promoting a shift towards plant- derived ... See full document

... professional role in terms of supporting their emotional ...with gynaecological malignancy must have ready access to the services of a clinical nurse ...demanding role. By securing and ... See full document

... Controversial results have been reported under dif- ferent conditions of experiments (Bisogno et al., 2007; Lafenêtre et al., 2007; Long et al., 2010; Viveros et al., 2007). It is hypothesized that the test conditions, ... See full document

... nervous system (CNS) [19] and to a lesser extent in peripheral metabolic tissues, including WAT, BAT, liver, myocardium, and skeletal muscle [21 – ...direct role of the ECS on adipose tissue ... See full document

... regulatory role in other medical condi- tions such as strokes and epilepsy ...key role in inducing mitochondrial dysfunction and lipid peroxidation which augment the rate of neuronal cell damage [68] ... See full document

... 71. de Luis D., Aller, R., Izaola, O., Díaz Soto, G., López Gómez, J., Gómez Hoyos, E., Torres, B., Villar, A. and Romero, E. Effects of a High-Protein/Low-Carbohydrate versus a Standard Hypocaloric Diet on Weight and ... See full document

... opioid system, and the brain and pituitary stress system in the addictive ...corticolimbic system represents a common neuronal substrate for the reinforcing properties of drugs of abuse, where both ... See full document

... WIN treatment triggered an autophagic process, as shown by accumulation of p62 and LC3; however, prolonged incuba- tion with WIN blocked an autophagic flux after autophago- some formation. Apparently, although autophagy ... See full document

... predict malignancy in endometrial ...which malignancy should be suggested owing to variations in the MRI system used and the number of b values used to generate the ADC ... See full document

... CB1, FAAH, IL-6 and TNF- a mRNA expression levels were measured by real-time RT-PCR. First, 1 μ g of total RNA was used for the reverse transcription reaction to synthesize the first-strand cDNA, using the random hexamer ... See full document

... Introduction Statistical data has shown that malignant brain tumors such as medulloblastomas and primitive neuroectodermal tumors (PNETs) are the most common solid cancers in children [1] . The 5-year relative survival ... See full document