[PDF] Top 20 Sepsis and disseminated intravascular coagulation
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Sepsis and disseminated intravascular coagulation
... in sepsis animal models and participate in the direct activation of the coagulation cascade in the early phases of sepsis ...and coagulation play an important role in DIC due to ...in ... See full document
8
A randomized, controlled, multicenter trial of the effects of antithrombin on disseminated intravascular coagulation in patients with sepsis
... having disseminated intravascular coagulation (DIC), demonstrated a significant reduction in mortality ...severe sepsis concluded that antithrombin might increase the overall survival of these ... See full document
10
An open-label, randomized, phase 3 study of the efficacy and safety of antithrombin gamma in patients with sepsis-induced disseminated intravascular coagulation syndrome
... with disseminated intravascular coagulation (DIC) [6], a life-threatening condition characterized by activated coagu- lation pathways, decreased anticoagulant activity, and al- tered activity of ... See full document
9
A multicenter, prospective validation study of the Japanese Association for Acute Medicine disseminated intravascular coagulation scoring system in patients with severe sepsis
... Disseminated intravascular coagulation (DIC) is a frequent complication of systemic inflammatory response syndrome (SIRS) ...[1]. Sepsis, defined as infection-induced SIRS, almost invariably ... See full document
8
Recent advances in disseminated intravascular coagulation: endothelial cells and fibrinolysis in sepsis-induced DIC
... or sepsis and is one of the most important predictors of multiple organ dysfunction during sepsis-induced disseminated intravascular coagulation ...in sepsis-induced ... See full document
8
Novel biomarkers for early prediction of sepsis-induced disseminated intravascular coagulation in a mouse cecal ligation and puncture model
... imitates sepsis by creating a bowel perforation with leakage of fecal material into the peritoneal ...grade sepsis-induced DIC, and ensured 85% mortality at 72 h ...of sepsis-induced DIC in the ... See full document
10
Efficacy of antithrombin in preclinical and clinical applications for sepsis-associated disseminated intravascular coagulation
... with sepsis-associated DIC have revealed that AT is potentially effective for DIC resolution and survival improvement without increasing the risk of ...during sepsis, the optimal method of identifying this ... See full document
7
New diagnostic strategy for sepsis induced disseminated intravascular coagulation: a prospective single center observational study
... with sepsis as well as in transplant and trauma patients ...vascular coagulation and inflammation; it is one of the basic regulatory systems of homeostasis, as it has potent anticoagulant, profibrinolytic ... See full document
9
Post-marketing surveillance data of thrombomodulin alfa: sub-analysis in patients with sepsis-induced disseminated intravascular coagulation
... for sepsis-induced DIC in daily clinical practice, and it col- lected prospective data and analyzed sepsis-induced DIC diagnosed according to the JAAM DIC criteria, which was not fully elucidated by the ... See full document
10
Sepsis-associated disseminated intravascular coagulation and its differential diagnoses
... with sepsis for the prevention of deep vein thrombosis and catheter management [83], sepsis patients are at high-risk of de- veloping ...with sepsis-associated DIC, espe- cially when it occurs in ... See full document
13
Effects of combination therapy using antithrombin and thrombomodulin for sepsis-associated disseminated intravascular coagulation
... had sepsis-associ- ated DIC and the greatest benefit from the treatment was seen in patients with at least one organ system dysfunc- tion and an PT international normalized ratio of greater than ... See full document
10
Quinine-Induced Disseminated Intravascular Coagulation
... 2.3. Treatment. The patient was admitted to the critical care unit and treated conservatively. Platelet count, coagu- lation profile, basic metabolic profile, and electrolytes were monitored daily. Offending agent ... See full document
5
Complement, thrombotic microangiopathy and disseminated intravascular coagulation
... Eculizmab™ is already in the market and several clinical tri- als for a variety of complement-driven diseases are on- going [50]. Anti-C5a was shown to ameliorate coagulation and fibrinolytic changes in a rat ... See full document
8
Reduction of D dimer levels after therapeutic administration of antithrombin in acquired antithrombin deficiency of severe sepsis
... Disseminated intravascular coagulation (DIC) is a systemic process potentially producing both thrombosis and hemor- ...of coagulation, such as protein C and antithrombin ...severe ... See full document
5
Classifying types of disseminated intravascular coagulation: clinical and animal models
... Disseminated intravascular coagulation (DIC) has a common pathogenesis in terms of persistent widespread activation of coagulation in the presence of underlying disease, but the degree of ... See full document
7
Clinical review: Molecular mechanisms underlying the role of antithrombin in sepsis
... In disseminated intravascular coagulation (DIC) there is extensive crosstalk between activation of inflammation and ...of coagulation and inflammation may theoretically be justified and have ... See full document
9
Neuroradiologic aspects of cerebral disseminated intravascular coagulation
... Principal autopsy findings were multiple large arterial vessel thrombi , including the pulmonary artery ; hepatic vein and segmental branch thrombi ; bilateral superficial middle cerebra[r] ... See full document
6
CARE OF THE CRITICALLY ILL CHILD: THE PROBLEM OF DISSEMINATED INTRAVASCULAR COAGULATION
... products of fibrin in human renal disease. : Care of the critically ill child: Endotoxin shock[r] ... See full document
9
Oral tranexamic acid combined with low molecular weight heparin only during dialysis sessions successfully controlled chronic disseminated intravascular coagulation associated with aortic aneurysm and aortic dissection in a dialysis patient: a case report with literature review
... Background: Disseminated intravascular coagulation (DIC) is a relatively rare but important cause of bleeding diathesis in patients on maintenance ... See full document
7
Metabolism of Fibrinogen in Cirrhosis of the Liver
... To substantiate the hypothesis of chronic disseminated intravascular coagulation, potentially associated with secondary activation of the fibrinolytic system, the metabolism of labeled f[r] ... See full document
13
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