[PDF] Top 20 Structural Basis for Human Norovirus Capsid Binding to Bile Acids
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Structural Basis for Human Norovirus Capsid Binding to Bile Acids
... for human noroviruses. Here, we resolve that bile acid was also a required cofactor that directly bound to the capsid for certain ...a norovirus virion likely interacts with bile acid ... See full document
17
Structural Basis for Norovirus Inhibition by Human Milk Oligosaccharides
... important binding factors for norovirus infections. We show that two human milk oligosaccharides, 2=-fucosyllactose (2=FL) and 3-fucosyllactose (3FL), could block norovirus from binding ... See full document
6
Structural Basis of Nanobodies Targeting the Prototype Norovirus
... ABSTRACT Human norovirus infections are a major disease ...new norovirus-specific Nanobodies that interacted with the pro- totype human norovirus ...the capsid- protruding (P) ... See full document
19
Structural Basis for the Recognition of Blood Group Trisaccharides by Norovirus
... on norovirus receptors show that different noroviruses recognize different human histo-blood group antigens (HBGAs), and eight receptor binding patterns of noroviruses have been ...the ... See full document
9
Structural Basis for Norovirus Inhibition and Fucose Mimicry by Citrate
... prevent human norovirus in- fections, and data on the mode of inhibition of fruits have been lacking, the stability of human norovirus virus-like particles over a pH range of 3 to 7 (3) ... See full document
9
Structural Basis for the Recognition of Lewis Antigens by Genogroup I Norovirus
... amino acids in the GI/2 (FUV258), GI/3 (Kashiwa 645), and GI/4 (Chiba) strains but is remarkably short in the GI/1 (NV/68 and SEV124) and GI/8 (WUG1) strains ...of binding to saliva from type O, A, and AB ... See full document
13
proteins NMR-based modeling and binding studies of a ternary complex between chicken liver bile acid binding protein and bile acids
... the binding pocket of cL-BABP based on multiple sets of NMR and mass spectrometry ...one binding site place severe demands on the docking procedures, and we show here the efficiency of the used multibody ... See full document
15
Structural Consequences of Cyclophilin A Binding on Maturational Refolding in Human Immunodeficiency Virus Type 1 Capsid Protein
... the basis of the relative staining intensities of the 24-kDa CA protein band, the eluates were matched for CA protein ...that binding to the mutant CyP A did not induce the structure change mediated by the ... See full document
13
Structural Basis for the Receptor Binding Specificity of Norwalk Virus
... recognize human histo-blood group antigens as receptors in a strain-specific ...the structural basis for differences in ligand recognition of noroviruses from different genogroups, the prototypic ... See full document
8
Capsid properties contributing to norovirus persistence in humans
... receptor binding region of GII.4 capsid structures can create changes in the repertoire of HBGAs they can ...encoding human HBGA catalization are polymorphic, such changes in receptor binding ... See full document
127
Structural Basis of Human Parechovirus Neutralization by Human Monoclonal Antibodies
... bivalent binding of the MAb, so we expected that the monova- lent binding of the MAb across the neighboring pentamers would be enough to stabilize the capsid (57–59, 63, ...virus capsid was ... See full document
10
Functional assessment and structural basis of antibody binding to human papillomavirus capsid
... the neutralization mechanism and the specific binding sites of neutralizing mAbs. 372[r] ... See full document
38
Structural Constraints on Human Norovirus Binding to Histo-Blood Group Antigens
... To confirm previously determined HBGA interactions, we expressed VP1 of HV GII.1 (GenBank accession number U07611), GII.10 (AF504671), and GII.12 (AB044366) in insect cells and examined VLP binding to PGM by ELISA ... See full document
7
Bile Acid Content of Human Serum II The Binding of Cholanic Acids by Human Plasma Proteins
... After equilibration with buffer or serum protein, the bile acid concentration in the outer solution was deter- mined spectrophotometrically (5, 6) on an aliquot of from 1 to 3 ml.4 The c[r] ... See full document
6
Identification and Characterization of Antibody-Binding Epitopes on the Norovirus GII.3 Capsid
... This suggests that antibodies elicited following a presumed noro- virus GII.3 infection during the 1970s or 1980s recognize the epitopes present on GII.3 noroviruses circulating at a similar time, as well as those ... See full document
11
Mutations within the P2 Domain of Norovirus Capsid Affect Binding to Human Histo-Blood Group Antigens: Evidence for a Binding Pocket
... in binding remains ...related binding patterns, and both strains belong to the same genogroup of ...and binding patterns is ...individual binding patterns have been ... See full document
11
Characterizing Human Norovirus Binding to Fresh Strawberries.
... HuNoV are extremely well adapted to persist through a diverse array of environmental conditions and readily bind to many surfaces, including fresh strawberries. There are no known methods currently available to remove or ... See full document
150
C-Terminal Arginine Cluster Is Essential for Receptor Binding of Norovirus Capsid Protein
... studied capsid and P proteins share the same primary sequences, their differences should be attributed to their tertiary or quaternary structure, which could be in turn environment ...the capsid protein/VLP ... See full document
10
The Structural Basis of Peptide-Protein Binding Strategies
... Peptide-protein interactions are very prevalent, mediating key processes such as signal transduction and protein trafficking. How can peptides overcome the entropic cost involved in switching from an unstructured, ... See full document
12
The Structural Basis for Microtubule Binding and Release by Dynein
... construct increases. Our work with the SRS-MTBD suggests that the further away from the microtubule surface, the less likely sufficient structural order will be present for sub-nanometer resolution ... See full document
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