[PDF] Top 20 Structure and function of IL-4 and IL-13 receptors on human B cells
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Structure and function of IL-4 and IL-13 receptors on human B cells
... CD40L. IL-13 is also active in antibody class switching. IL-4 was originally thought to be the only cytokine capable of switching B cells to the production of lgG4 and IgE, but ... See full document
280
Human Breast Carcinoma Cells Express Type II IL-4 Receptors and Are Sensitive to Antitumor Activity of a Chimeric IL-4-Pseudomonas Exotoxin Fusion Protein in vitro and in vivo
... cancer cells may help generate targeted anti- breast cancer ...target human breast ...ErbB-4 receptors, is connected to a truncated form of Pseudomonas exotoxin ...cer cells that ... See full document
14
Interleukin-1 participates in the classical and alternative activation of microglia/macrophages after spinal cord injury
... that IL-1b triggers the proliferation and early differentiation of neural progeni- tor cells during development of the spinal cord and after hippocampal injury ...that IL-1b levels remained high up ... See full document
17
High salt reduces the activation of IL 4– and IL 13–stimulated macrophages
... M(IL- 4+IL-13) ...Th17 cells (22) and M(LPS) macrophages (18), we revealed that sodium medi- ated its effect by boosting a proinflammatory SGK1-NFAT5 sig- naling ...so ... See full document
17
Lymphomagenesis, hydronephrosis, and autoantibodies result from dysregulation of IL 9 and are differentially dependent on Th2 cytokines
... of IL-9 has been detected in Hodgkin’s lymphoma cell lines and in the neoplastic Reed-Sternberg cells of primary Hodgkin’s tumors, indicating that IL-9 may play a role in the de- velopment of ... See full document
10
Interleukin (IL) 4 and IL 13 act on human lung fibroblasts Implication in asthma
... that IL-4 and IL-13 act on human lung fibroblasts by increasing the expression of cell surface b 1 integrin and VCAM-1 adhesion molecules and the secretion of some of the ... See full document
12
Intra-pancreatic tissue-derived mesenchymal stromal cells: a promising therapeutic potential with anti-inflammatory and pro-angiogenic profiles
... stromal cells (MSCs) have the potential for treating various diseases ...the function of pancreatic β-cells, reduced the incidence of diabetic com- plications, and led to insulin independence in some ... See full document
14
Expression of high affinity interleukin 4 receptors on human renal cell carcinoma cells and inhibition of tumor cell growth in vitro by interleukin 4
... for IL-4R gene expression, performed with a cDNA probe to IL-4R, revealed that all RCC cells exhibited a single mRNA species of 4 ...kb. IL-4 downregulated the surface expression ... See full document
7
Allergen induced IL 9 directly stimulates mucin transcription in respiratory epithelial cells
... USA). Human GAPDH primers were 3′: GGG GTC TAC ATG GCA ACT GTG AGG AGG GGA and 5′: AAA CCT GCC AAA TAT GAT GAC ATC AAG AAG ; human MUC5AC primers 3′: TCA CAG CCG GGT ACG CGT TGG CAC AAG TGG and 5′: TGC TAT ... See full document
9
Therapeutic vaccines based on Mycobacterium vaccae for treatment of an established IgE response to ovalbumin in BALB/c mice
... naive human T cells into the Th2 pathway mainly depends on the levels and the kinetics of autocrine IL-4 production at ...to IL-4 from accessory cells and may be ... See full document
195
Interleukin-4 inhibits secretion of interleukin-1beta in the response of human cells to mycobacterial heat shock proteins.
... of IL-1 b have been found in response to mycobacterial antigens by testing human cells from the synovial infiltrates of RA patients (14, ...of IL-4 on proinflammatory cytokine ... See full document
6
Modulation of experimental atopic dermatitis by topical application of Gami Cheongyeul Sodok Eum
... as IL-4, IL- 5, and ...[6,8,33]. IL-4, IL-5 and IL-13 are typical Th2 type cytokines that stimulate Th2 differentiation and IgE production by B cells ... See full document
10
IL 1 Receptor Type II Production Is Upregulated by IL 4 and IL 13, and Downregulated by IFN γ in Mouse Gingival Epithelial Cells
... that human gingival fibroblasts overexpressed IL-1RII, which regulated the mRNA expression of IL-1β ...[12]. IL-1RII expression was also shown to be decreased in stromal and epithelial ... See full document
11
A study of b cell responses induced by IL-4 and IL-13
... The human yc was first identified as a component of the IL-2 receptor (Takeshita et ...The human gene produces a RNA species of ...genomic structure of the human yc gene consists of 8 ... See full document
266
Dynamics of IL-4 and IL-13 expression in the airways of sheep following allergen challenge
... epithelial cells [31] the most likely ...on IL-6 signalling, al- though the contribution of classical or IL-6 trans- signalling, as recently investigated in mice and human subjects [57], is ... See full document
11
Alterations of serum biomarkers associated with lung ventilation function impairment in coal Workers: A cross-sectional study
... A previous study from our laboratory demonstrated that levels of serum MMP-9 in asymptomatic miners were significantly lower when compared with the levels in healthy control subjects who had no coal dust expo- sure [22]. ... See full document
8
Dupilumab: a novel treatment for asthma
... after 4 weeks and to progressively reduce and then suspend their ICS therapy between weeks 6 and ...after 4 weeks of treatment, and persisted up to week 12 at lower levels than baseline values, in spite of ... See full document
8
Human recombinant granulocyte macrophage colony stimulating factor and interleukin 3 cause basophil histamine release
... of human cells, including T lymphocytes and alveolar ...on human basophils and/or mast cells and therefore tested preparations of human recombinant IL 3, IL 4, ... See full document
5
Soshiho tang water extract inhibits ovalbumin induced airway inflammation via the regulation of heme oxygenase 1
... antigen-presenting cells to CD4 + T cells. Antigen-activated CD4 + T cells induce several character- istic features of asthma, including the secretion of Th2- type cytokines such as ... See full document
10
IL 10 producing regulatory B cells (B10 cells) in autoimmune disease
... of B cells in autoimmune disease was thought to be predominantly limited to the production of ...production, B cells have other functions potentially relevant to ...T cells, expression ... See full document
12
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