[PDF] Top 20 A study of b cell responses induced by IL-4 and IL-13
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A study of b cell responses induced by IL-4 and IL-13
... between IL-4 dose responses for sIgM and CD23 ...afhnity IL-4 ...to IL-4 activity through the IL-4 and IL-13 ...X-SCID B cells suggest ... See full document
266
The IL 4/IL 13/Stat6 signalling pathway promotes luminal mammary epithelial cell development
... was induced at day 5 of gestation and maintained until lactation ...of IL-4R ␣ and Gata3 increased from day 10 of gestation, whereas c-Maf was increased later, from day 15 of ...and IL-4R ␣ was ... See full document
12
High salt reduces the activation of IL 4– and IL 13–stimulated macrophages
... M(IL- 4+IL-13) ...current study, we found no evidence for Sgk1 or Nfat5 in mediating the effect of salt on M(IL-4+IL-13) activation; however, this is in fact ... See full document
17
Original Article Expression of IL-4 and IL-13 predicts recurrence and survival in localized clear-cell renal cell carcinoma
... this study that warrant further ...of IL-4 and IL-13 expression needs to be validated in other populations and larger ...of IL-4 and IL-13 expression in ... See full document
10
Interleukin-1 participates in the classical and alternative activation of microglia/macrophages after spinal cord injury
... that IL-1b triggers the proliferation and early differentiation of neural progeni- tor cells during development of the spinal cord and after hippocampal injury ...present study, we found that IL-1b ... See full document
17
Inflammatory patterns of antrochoanal polyps in the pediatric age group
... previous study, decreased Treg cells infiltration in ACP compared to NP and inferior turbinate mucosa from control on histopathology ...cytokine, IL-10 was increased in whole ACP compared to controls in our ... See full document
7
Simultaneous disruption of Interleukin (IL) 4 and IL 13 defines individual roles in T Helper cell Type 2 mediated responses
... encoding IL-4 and IL-13 are closely linked on human chromosome 5 and the syntenic region of mouse chromosome 11, and map to a cytokine gene cluster that also includes IL-5, IL-3, ... See full document
8
Oestrogen receptor negative breast cancers exhibit high cytokine content
... present study we screened 17 members of the cytokine family (IL-1β, IL-2, IL-4, IL-5, IL-6, IL-7, IL-8, IL- 10, IL-12 [p70], ... See full document
11
Dynamics of IL-4 and IL-13 expression in the airways of sheep following allergen challenge
... present study, there was an initial decline ob- served in AM numbers following allergen challenge but also a clear shift in their functional phenotype, with an increase in the proportion of IL-4 (24 ... See full document
11
Adenosine mediates IL 13–induced inflammation and remodeling in the lung and interacts in an IL 13–adenosine amplification pathway
... COPD. IL-13 was originally described as an IL-4–like cytokine and noted to have effector properties rele- vant to Th2 ...that IL-13 is a powerful regulator of tissue inflammation ... See full document
14
T Helper 2 Cytokines Inhibit Autophagic Control of Intracellular Mycobacterium tuberculosis
... specifically study alternative activation of macrophages by IL-4 and IL-13 (Gordon, 2003) but instead focused on the effects of short-term ex- posure (2 hr) or treatment in combination ... See full document
13
Investigational therapeutics targeting the IL-4/IL-13/STAT-6 pathway for the treatment of asthma
... placebo-controlled study of anrukinzumab was completed in Canada in patients (n 5 27) with mild, atopic asthma ...primary study endpoint was maximum change in FEV 1 post-allergen challenge during early and ... See full document
9
<p>IL-33/13 Axis and IL-4/31 Axis Play Distinct Roles in Inflammatory Process and Itch in Psoriasis and Atopic Dermatitis</p>
... a study by Neis et al, the mRNA levels of IL-31 were shown to be increased in AD lesions but not psoriatic plaques and the levels of IL-31 in AD lesions correlated with the expression of ... See full document
6
Therapeutic vaccines based on Mycobacterium vaccae for treatment of an established IgE response to ovalbumin in BALB/c mice
... whereas cell-mediated immunity is more important for the elimination of intracellular ...the study of inbred mice has accumulated to suggest that this reciprocal relation between humoral and cellular ... See full document
195
Th2 responses induced by epicutaneous or inhalational protein exposure are differentially dependent on IL 4
... adjuvant, induced strong Th2 ...IgG1(both induced by IL-4), and little IgG2a, the murine isotype associated with IFN-γ production by Th1 cells (41, ...lung responses with ... See full document
12
Lymphomagenesis, hydronephrosis, and autoantibodies result from dysregulation of IL 9 and are differentially dependent on Th2 cytokines
... of IL-9 has been detected in Hodgkin’s lymphoma cell lines and in the neoplastic Reed-Sternberg cells of primary Hodgkin’s tumors, indicating that IL-9 may play a role in the de- velopment of human ... See full document
10
Lack of association or interactions between the IL 4, IL 4Rα and IL 13 genes, and rheumatoid arthritis
... The IL-4R I50V variant has been associated with increased radiological damage during the first 2 years of disease [7], but we did not observe such an ...in study design; our study is composed of a ... See full document
7
HSP90 inhibitor geldanamycin reverts IL 13– and IL 17–induced airway goblet cell metaplasia
... the IL-13 receptor (IL-13R) complex, it hypothetically might revert established gob- let cell metaplasia, even when exposure to IL-13 ...to IL-13 for 21 days to ... See full document
16
Modulation of experimental atopic dermatitis by topical application of Gami Cheongyeul Sodok Eum
... induce cell death (Figure ...CD19+ B cells isolated from AD-induced mice. Upon LPS/IL-4 stimulation, GCSE treatment significantly re- duced IgE production by B cells in a dose ... See full document
10
Interleukin (IL) 4 and IL 13 act on human lung fibroblasts Implication in asthma
... transduction induced in the three types of fibroblasts by IL-4 and IL-13 seem to be associated with different biological ...with IL-4 and IL-13, no VCAM-1 ... See full document
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