[PDF] Top 20 Suppression of hepatitis B virus expression and replication by hepatitis C virus core protein in HuH-7 cells.
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Suppression of hepatitis B virus expression and replication by hepatitis C virus core protein in HuH-7 cells.
... To elucidate the molecular status of superinfection with these two hepatitis viruses, we cotransfected the full-length or truncated version of HCV structural genes core and envelope 1 to[r] ... See full document
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Modulation of the trans-suppression activity of hepatitis C virus core protein by phosphorylation.
... the core protein of hepatitis C virus (HCV) can suppress gene expression and replication of hepatitis B virus (HBV) in a human hepatoma cell line ... See full document
12
Interaction of Hepatitis C Virus Core Protein with Viral Sense RNA and Suppression of Its Translation
... HCV core protein suppresses its own translation by interacting with its ...in cells infected with the recombi- nant baculovirus AcCA816, AcCAlacZ, or AcCAG ...of core protein ... See full document
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Effect of Hepatitis C Virus Core Protein on the Molecular Profiling of Human B Lymphocytes
... gene expression in forward and reverse labeling of control samples was shown to be highly correlated and ensured dye la- beling ...from B cells infected with Ade-β-gal (Cy5), and B ... See full document
7
Posttranscriptional regulation of hepatitis B virus replication by the precore protein.
... two core-related open reading ...p21 core protein, which subsequently becomes a structural component of the viral ...precore protein that is targeted by a signal peptide to a cell secretory ... See full document
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Prohibitin is overexpressed in Huh 7 HCV and Huh 7 5 HCV cells harboring in vitro transcribed full length hepatitis C virus RNA
... conserved protein, and it is widely distributed in bacteria, plants, fungi, protozoa, and mammals ...multifunctional protein that localizes at different intracellular ...membrane protein superfam- ... See full document
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MicroRNA 130a Regulates both Hepatitis C Virus and Hepatitis B Virus Replication through a Central Metabolic Pathway
... ABSTRACT Hepatitis C virus (HCV) infection has been shown to regulate microRNA 130a (miR-130a) in patient biopsy specimens and in cultured ...and hepatitis B virus (HBV) ...HCV ... See full document
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Point Mutations Upstream of Hepatitis B Virus Core Gene Affect DNA Replication at the Step of Core Protein Expression
... lacking core protein expression (core ⫺ 4B genome) and with defective polymerase expression and nonfunctional encapsidation signal (Pol ⫺ /ε ⫺ 4B genome) were employed in the ... See full document
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Hepatitis C Virus Core Protein Leads to Immune Suppression and Liver Damage in a Transgenic Murine Model
... Hepatitis C virus (HCV) is remarkably efficient in establishing persistent infection, possibly mediated by an impaired immune response to HCV ...immune cells, such as macrophages, B ... See full document
10
Macrophages in Hepatitis B and Hepatitis C Virus Infections
... stellate cells and hepatocytes ...envelope protein expression, KCs exhibiting high levels of superoxides are observed specifically beside proliferating hepatocytes ...HCV core- and NS5A- ... See full document
7
Expression of Hepatitis C Virus Core Protein in Hepatocytes Does Not Modulate Proliferation or Apoptosis of CD8+ T Cells
... gene expression in ...HCV core and EGFP-OVA. (B) Primary mouse hepatocytes were observed after 24 h of infection with baculo- virus expressing ...Liver cells infected with baculovirus ... See full document
8
Conditional Replication of Duck Hepatitis B Virus in Hepatoma Cells
... the protein-priming reaction for reverse transcription ...of core particles containing pgRNA and at least four nucleotides of minus strand DNA ...the cells were incubated with and without ... See full document
9
The Hepatitis B Virus X Protein Transactivates Viral Core Gene Expression In Vivo
... Immunohistology. Tissue specimens were fixed in 4% formaldehyde solution in phosphate-buffered saline (pH 7.2). HBcAg-specific immunostaining was per- formed with paraffin sections using the avidin-biotin complex method ... See full document
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Hepatitis B Virus Replication and Release Are Independent of Core Lysine Ubiquitination
... Huh7 cells grown on glass coverslips were transfected with the HBV expression plas- ...These cells were used for immunofluorescence because HBV-Met and TRE-HBV cells adhere poorly to ... See full document
11
Expression of an IRF 3 fusion protein and mouse estrogen receptor, inhibits hepatitis C viral replication in RIG I deficient Huh 7 5 cells
... (ISG) expression en route for restraining hepatitis C virus (HCV) ...fusion protein of IRF-3 and mouse estrogen receptor (ER) to examine IFN production and anti-HCV effects of IRF-3 in ... See full document
8
Natural history and treatment of hepatitis B virus and hepatitis C virus coinfection
... HBV replication, as demonstrated by studies showing that patients with chronic hepatitis B who are coinfected with HCV have lower HBV DNA levels, decreased activity of HBV DNA polymerase, and ... See full document
12
Epigenetic Silencing of Antiviral Genes Renders Clones of Huh-7 Cells Permissive for Hepatitis C Virus Replication
... how expression of CREB3L1 is suppressed in HRP1 cells, we performed extensive sequencing analysis but were unable to identify any mutation in the coding region or in the 5= regula- tory element of the gene ... See full document
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Activity-based protein profiling of the hepatitis C virus replication in Huh-7 hepatoma cells using a non-directed active site probe
... (nine protein classes were identified in this study) (Figure 5A) could be reflected by the diversity of amino acids known to be labeled by the PS4≡ probe (aspartate, cysteine, gluta- mate, and tyrosine) [27], ... See full document
15
Hepatitis B Virus DNA Replication Is Coordinated by Core Protein Serine Phosphorylation and HBx Expression
... of core protein dimers and/or capsids with their viral nucleic acids into the nucleus (19, 23, 34), although it is not clear whether this modification might simply favor capsid ...HBV, core ... See full document
11
Identification of the Hepatitis C Virus RNA Replication Complex in Huh-7 Cells Harboring Subgenomic Replicons
... naive Huh-7 ...replicon cells. (a) 9-13 replicon cells were labeled with NS5A-specific MAb 11H (7; kindly provided by Jan Albert Hellings, Organon Teknika ...naive Huh-7 ... See full document
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