[PDF] Top 20 Testing the activitystat hypothesis: a randomised controlled trial protocol

... This protocol has been specifically designed to test the activitystat hypothesis while taking into account the key conceptual and methodological considerations of testing a biologically ... See full document

... After completing all baseline data collection measures, participants are randomised to either intervention group protocols or control group protocols for 12 weeks or until healed. Participants in the intervention ... See full document

... In the full trial, we plan to calculate the cost-effectiveness of Pregnancy Circles compared to control from concep- tion until 4 months postpartum. NICE recommend that cost-effectiveness is calculated as the cost ... See full document

... a randomised controlled trial (RCT) with N = 182 adolescents aged 12 – 16, allocated to either the target intervention plus treatment as usual (OVK + TAU) or treatment as usual only ... See full document

... pilot trial is important to assess the best methods for conducting this proposed randomised controlled trial of this model of group antenatal care in the ...full trial (see Table 1) ... See full document

... the Trial to Incentivise Adherence for Diabetes (TRIAD) we test whether adding financial incentives to usual care can improve HbA1c levels among people with diabetes and whether the financial incentives work ... See full document

... and testing complex interventions [34, 35], the purpose of this research is to assess the feasibility and acceptability of delivering a midwife-led group inter- vention to reduce levels of anxiety in pregnant ... See full document

... After anteroposterior and lateral scanograms, a non- enhanced scan will be performed using prospective ECG triggering over a single heartbeat with a gantry rotation and x-ray exposure time of 0.35 s, 0.5-mm slice ... See full document

... placebo-controlled, randomised trial is currently underway to address this ...injury trial is a stratified prospective, multi-centre, randomised, blinded, parallel-group, ... See full document

... This protocol is for a pilot randomised trial to evaluate the feasibility of conducting a larger trial and will compare a moisturising oil versus no treatment for the prevention and reduction ... See full document

... previous trial in which all participants were undertaking an exercise programme ...to testing whether ACEi drugs really have clinically relevant benefit in the target population for this commissioned call ... See full document

... The protocol has been developed according to the SPIRIT 2013 statement [10], follows the CONSORT statement [11], and is registered in ...the protocol for a study where the main aim is to assess the effects ... See full document

... This paper has presented the theoretical rationale, as well as the protocol, for a RCT that is testing the efficacy of specially-designed unloading shoes for managing the symptoms of knee OA. The findings ... See full document

... parallel, randomised sham-controlled trial with equal allocation of participants to two trial ...are randomised to receive either true needle acupuncture or sham acupuncture with ... See full document

... satisfaction and improved performance in key areas such as communication skills [7]. Patient narratives involving patients sharing their stories with professionals are now widely employed as part of medical training and ... See full document

... We will use intention to treat analysis; all participants will be included in their randomised groups, whether or not they have received their allocated treatment. The primary outcome will be the IBS SSS at three ... See full document

... Methods/design: This study is a randomised, double-blinded and placebo-controlled, multicentre trial. It has two parallel arms: the Euiiyin-tang group and the placebo group. A total of 160 obese ... See full document

... A number of recent findings suggest that cost-effectiveness studies in the public domain may represent a biased sam- ple of the population of economic evaluations [14,15]. It is possible that this finding reflects a ... See full document

... the trial by clinic midwives or via self-referral; these women will need to undergo a detailed assessment of their eligibility for the ...the trial and will just need to be asked some additional ...the ... See full document

... The Data Safety Monitoring Committee (DSMC) consists of independent experts (medical experts and a statisti- cian) external to a trial who assess the progress, conduct, participant safety and critical endpoints of ... See full document