[PDF] Top 20 The multidimensional mechanisms of long noncoding RNA function
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The multidimensional mechanisms of long noncoding RNA function
... lncRNA function are strictly dependent on the inherent properties of the RNA molecules, including their ability to fold into different structures and to conduct molecular interac- tions with other nucleic ... See full document
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Long Noncoding RNA: Recent Updates in Atherosclerosis
... distal X-chromosome by identifying the three-dimen- sional structure of the X-chromosome [8]. Fendrr specifically binds to PRC2 and guides PRC2 to the promoters of Foxf1 in cis and Pitx2 in trans [9]. ANRIL could work as ... See full document
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Functions and mechanisms of long noncoding RNAs in lung cancer
... indicated that the conservation of lncRNAs should include four dimensions: sequence, structure, function, and expres- sion from synthetic loci. Despite the differences between lncRNAs and mRNAs, they share certain ... See full document
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Multiplicity in Long Noncoding RNA in Living Cells
... has long been considered that the structures and functions of macromolecules, such as proteins and nucleic acids, inside the living cells are different from those in in vitro ... See full document
6
<p>The Long Noncoding RNA ZFAS1 Potentiates the Development of Hepatocellular Carcinoma via the microRNA-624/MDK/ERK/JNK/P38 Signaling Pathway</p>
... Long noncoding RNAs (lncRNAs) represent a group of non-protein coding RNAs that were regarded as genomic “ junk ” and “ noise ” at the beginning ...to function as potent oncogenes or tumor ... See full document
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Induction of long noncoding RNA MALAT1 in hypoxic mice
... Abstract: Long thought to be “junk DNA”, in recent years it has become clear that a substan- tial fraction of intergenic genomic DNA is actually transcribed, forming long noncoding RNA ... See full document
8
Prognostic significance of the long noncoding RNAs in nasopharyngeal carcinoma: a systematic review and meta-analysis
... molecular mechanisms by which the lncRNAs regulate carci- nogenesis and metastasis are expected to be ...their function and association with various cancer subtypes, and developing novel lncRNA-based ... See full document
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<p>Long Non-Coding Small Nucleolar RNA Host Genes (SNHGs) in Endocrine-Related Cancers</p>
... and function (eg proliferation, inva- sion, migration, apoptosis, autophagy, and chemoresistance) in multiple endocrine-related ...various mechanisms, including direct regulation (promotion or inhibition) ... See full document
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Expression of the Antisense-to-Latency Transcript Long Noncoding RNA in Kaposi's Sarcoma-Associated Herpesvirus
... (PAN) RNA, has been known for 2 decades (22, ...PAN RNA is either not expressed or expressed at low basal levels during latency (33, 34) and then is induced to higher levels during lytic reacti- vation; ... See full document
18
Decoding Noncoding RNAs: Role of MicroRNAs and Long Noncoding RNAs in Ocular Neovascularization
... by RNA Pol II from genomic loci as the miRNAs [26], nonetheless, they may be 5ʹ ‑ capped, spliced, and 3’-polyadenylated in unconventional ...or RNA target structures. Collectively, lncRNAs can ... See full document
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Structure of noncoding RNA is a determinant of function of RNA binding proteins in transcriptional regulation
... the N-terminal of the glutamine-rich domain, RRM, ZnF and other RGG domains did not [60]. The carboxy- terminal RGG domain of EWS contributes not only to the binding to G-quadruplex RNA but also that to G- ... See full document
8
Analyzing the lncRNA, miRNA, and mRNA-associated ceRNA networks to reveal potential prognostic biomarkers for glioblastoma multiforme
... Noncoding RNAs (ncRNAs), a class of RNAs with limited protein encoding abilities that are commonly expressed in many tumors including GBM, have received considerable attention [7]. The lncRNAs, a subtype of ncRNA ... See full document
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Reprogramming of Small Noncoding RNA Populations in Peripheral Blood Reveals Host Biomarkers for Latent and Active Mycobacterium tuberculosis Infection
... as biomarkers for patient classification and (pending a better understanding of their physiological functions) as tools for new insights into pathophysiological mechanisms. SNORD104, also known as U104, is ... See full document
23
Long noncoding RNA SNHG6 promotes the progression of colorectal cancer through sponging miR-760 and activation of FOXC1
... its function by sponging miR-760 and activating ...Nevertheless, long non-coding RNA could play crucial roles in many different ...or RNA binding proteins, and subsequently regulate the ... See full document
10
Expressions of Long Non Coding RNAs in Carcinogenesis of Cervix: A Review
... DOI: 10.4236/ojog.2018.82017 137 Open Journal of Obstetrics and Gynecology lncRNA located in the 8q24 chromosomal region of the human genome which is also the commonest sites of cancer-related amplifications containing ... See full document
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Long noncoding RNA expression profiles in sub lethal heat treated hepatoma carcinoma cells
... specimens during or after RFA treatment because HCC biopsies are controversial in our institution (rarely produced). Therefore, HCC tissue specimens were not used for microarray analysis. So, we will quantify ... See full document
14
A Lytic Viral Long Noncoding RNA Modulates the Function of a Latent Protein
... of noncoding RNAs, called long noncoding RNAs (lncRNAs), are defined as RNA polymerase II (Pol II)-transcribed noncoding RNAs greater than 200 nucleo- tides in length ...nuclear ... See full document
6
The Long Noncoding RNA HEAL Regulates HIV 1 Replication through Epigenetic Regulation of the HIV 1 Promoter
... provirus. Long noncoding RNAs (lncRNAs, ⬎ 200 nucleotides) are increasingly recognized to play important roles in ...the RNA-binding protein FUS, which facilitates HIV replication through at least ... See full document
18
Long non coding RNA repertoire and targeting by nuclear exosome, cytoplasmic exonuclease and RNAi in fission yeast
... Long noncoding RNAs (lncRNAs), which are longer than 200 nucleotides but often unstable, contribute a substantial and diverse portion to pervasive noncoding ...on RNA-seq data from twelve ... See full document
20
Insights into long noncoding RNAs of naked mole rat ( Heterocephalus glaber ) and their potential association with cancer resistance
... The function of lncRNA 1169 in the NMR is not clear, but BLASTN searching of lncRNA 1169 as well as the other four NMR-HCRLs against the NON- CODE database found BLAST hits on the queries, not only in human but ... See full document
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