[PDF] Top 20 Theiler's virus as a vector for foreign gene delivery.
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Theiler's virus as a vector for foreign gene delivery.
... DA virus that contains an insertion of an enceph- alitogenic PLP peptide (that is known to produce an autoim- mune demyelinating disease in SJL mice [25]) may determine whether there is an enhanced capacity for ... See full document
5
Delivery of Factor VIII Gene into Skeletal Muscle Cells Using Lentiviral Vector
... adeno-associated virus (AAV) vectors into skeletal muscles, and showed sufficient expression of FVIII in the skeletal muscles and proven that AAV vectors could produce FVIII in the skeletal ...this gene ... See full document
6
Improved Hepatic Gene Transfer by Using an Adeno-Associated Virus Serotype 5 Vector
... these vector doses has not been demonstrated before using an AAV vector, and recent data from others have also demonstrated improved efficacy of hepatic gene transfer with the AAV-5 serotype ...of ... See full document
6
Self-contained, tetracycline-regulated retroviral vector system for gene delivery to mammalian cells.
... tTA gene), which is under the transcriptional control of internal SV40 or JC virus promoter, and the response unit, which is under the transcriptional control of a minimal CMV promoter (lacking enhancers) ... See full document
6
Yaba-Like Disease Virus: an Alternative Replicating Poxvirus Vector for Cancer Gene Therapy
... cancer gene therapy (4, 25). They have been investigated as vectors for delivery of tumor-associated antigens, cytokines, and costimulatory molecules in cancer pa- tients, for the development of an ... See full document
9
Intrathecal Adeno-Associated Virus Vector Delivery for Mucopolysaccharidosis Type I
... associated virus genome could be provided in trans, allowing for the generation of infectious particles in which the endogenous genome was replaced with a transgene (Samulski, Chang, and Shenk 1989, ... See full document
161
Recombinant Vaccinia Virus-Induced T-Cell Immunity: Quantitation of the Response to the Virus Vector and the Foreign Epitope
... the foreign gene(s) expressed by the ...viral vector and the insert following the infection of mice with VV expressing a cytotoxic T lymphocyte (CTL) epitope (NP118–126) from lymphocytic ... See full document
9
Structure of Adeno-Associated Virus Serotype 8, a Gene Therapy Vector
... the delivery of the corrective genes into the target cells and long- term expression of the genes have been two major challenges of this treatment ...potential gene therapy vectors which can deliver ... See full document
12
High-Titer Human Immunodeficiency Virus Type 1-Based Vector Systems for Gene Delivery into Nondividing Cells
... immunodeficiency virus type 1 (HIV-1) vectors to deliver genes into nondividing cells ...a vector construct harboring a reporter gene such as neo, ShlacZ (encoding a phleomycin resistance/ b ... See full document
11
Vector design influences hepatic genotoxicity after adeno associated virus gene therapy
... AAV gene therapy and survey for long-term ...AAV gene delivery and used a novel high-throughput integration site-capture technique to locate AAV insertions in tumors and matched control tissues, ... See full document
12
Rapid Delivery of Foreign Genes into Plants by Direct Rub-Inoculation with Intact Plasmid DNA of a Tomato Bushy Stunt Virus Gene Vector
... that foreign proteins can be expressed from modified TBSV sgRNA1 that contains an elongated leader promoting translational initiation at the au- thentic start codon on the foreign ... See full document
7
A Respiratory Syncytial Virus Replicon That Is Noncytotoxic and Capable of Long-Term Foreign Gene Expression
... of foreign genes, as shown here by the example of GFP and the blasticidin S deaminase ...cytoplasmic vector for long-term gene expression in cultured ...luciferase gene into the RSV ... See full document
10
Rescue of Infectious Rift Valley Fever Virus Entirely from cDNA, Analysis of Virus Lacking the NSs Gene, and Expression of a Foreign Gene
... fever virus (RVFV) (genus Phlebovirus, family Bunyaviridae) has a tripartite negative-strand genome, causes a mosquito-borne disease that is endemic in sub-Saharan African countries and that also causes large ... See full document
8
Peptide Mediated Tumor Targeting by a Degradable Nano Gene Delivery Vector Based on Pluronic Modified Polyethylenimine
... a gene carrier ...PEI delivery relies simply on the electrostatic attraction be- tween the positively charged polymer and negatively charged cells, which is ... See full document
13
An Avian Sarcoma/Leukosis Virus-Based Gene Trap Vector for Mammalian Cells
... leukosis virus (ASLV) (11, 14, ...env gene encoding the ASLV envelope glycopro- tein with the env gene of the amphotropic murine leukemia virus (MLV) ...resulting virus, RCASBP-M2C, is ... See full document
7
Dendrimers in gene delivery
... non-viral delivery systems, which all have distinct advantages and disadvantages ...any gene delivery system will always have to be matched with the clinical situation, the specific disease and the ... See full document
26
Persistent Gene Expression in Mouse Nasal Epithelia following Feline Immunodeficiency Virus-Based Vector Gene Transfer
... The vector was applied to the apical or basolateral surface of the epithelial sheet for 4 ...lowing vector delivery, gene transfer was quantified by mea- suring  -galactosidase ...date. ... See full document
10
Bioreducible and acid-labile poly(amido amine)s for efficient gene delivery
... significant gene transfection ability, which was higher than for nonresponsive or single-responsive ...rent vector is easy to disassemble in the systemic circulation, the principle described in the current ... See full document
14
Guanidinylated bioresponsive poly(amido amine)s designed for intranuclear gene delivery
... bromide (MTT) were purchased from Sigma-Aldrich Co. (St Louis, MO, USA). Lipofectamine 2000 (Lipo) reagent, Dulbecco’s Modified Eagle’s Medium, fetal bovine serum (FBS), penicillin, streptomycin, and trypsin were ... See full document
14
Recovery of infectious respiratory syncytial virus expressing an additional, foreign gene.
... Construction of cDNA encoding RSV antigenomic RNA con- taining the CAT gene. We previously constructed cDNA D46, which encodes a complete, 15,223-nucleotide RSV antigenome (one nucleotide longer than that of ... See full document
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