[PDF] Top 20 Turnover of Hepatitis B Virus X Protein Is Regulated by Damaged DNA-Binding Complex
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Turnover of Hepatitis B Virus X Protein Is Regulated by Damaged DNA-Binding Complex
... stabilized protein might ensure its efficient recruitment into a particular functional pathway by the other ...stabilized protein is the target of a chaperone, which assists it in acqui- sition of a ... See full document
7
Hepatitis B Virus X Protein Interferes with Cellular DNA Repair
... abolished binding to UVDDB even though aa 61 lies out- side the minimal domain defined by Sitterlin et ...to binding damaged DNA, UVDDB may have a role in transcription, as has been described ... See full document
7
Spatiotemporal Analysis of Hepatitis B Virus X Protein in Primary Human Hepatocytes
... HBx protein levels and leads to reappearance of Smc6 in HBV-infected ...HBx protein levels could be reduced by RNA interference and whether this would lead to the reappearance of the Smc5/6 complex ... See full document
16
Altered DNA Mutation Spectrum in Aflatoxin B1-Treated Transgenic Mice That Express the Hepatitis B Virus X Protein
... UV-damaged DNA binding protein (DDB1 [also known as UV-DDB]) component of NER, mutant cII plaques from ATX and WT mice were isolated and sequenced, to determine whether the interaction ... See full document
5
Drosophila Damaged DNA-Binding Protein 1 Is an Essential Factor for Development
... HE damaged DNA-binding protein (DDB) com- tants) are selectively defective in global genomic repair plex, which is a heterodimeric protein composed (GGR; Hwang et ...of DNA ... See full document
12
Hepatitis B Virus X Protein Is both a Substrate and a Potential Inhibitor of the Proteasome Complex
... Hepatitis B virus (HBV) has a unique fourth open reading frame (ORF) coding for a protein known as hepatitis B virus X (HBX) (for reviews, see references 3, 10 and ... See full document
10
Proteasome complex as a potential cellular target of hepatitis B virus X protein.
... The X gene of woodchuck HBV derived from the WHV81 strain was fused to the lexA DNA binding domain through the NcoI site of woodchuck HBV (nucleotide 1501), which contains the AUG start codon of ... See full document
10
Hepatitis B virus X protein interacts with a probable cellular DNA repair protein.
... a protein that binds to damaged DNA and that may represent the defective protein in XP group E patients (15, ...the protein (XPE-binding factor) from human ...high binding ... See full document
8
Hepatitis B Virus X Protein and Simian Virus 5 V Protein Exhibit Similar UV-DDB1 Binding Properties To Mediate Distinct Activities
... the X protein of hepatitis B virus ...regulatory protein that is well conserved among the mammalian members of the family Hepadnaviridae, which also includes the hepatitis ... See full document
10
Interaction of the UV-damaged DNA-binding protein with hepatitis B virus X protein is conserved among mammalian hepadnaviruses and restricted to transactivation-proficient X-insertion mutants.
... In order to confirm these results on a more quantitative basis, we performed a similar analysis in the LexA-based two- hybrid system using the lacZ reporter gene. All HBx mutants affected in their transactivation ... See full document
6
Hepatitis B Virus X Protein Function Requires Zinc Binding
... 5/6 complex (Smc5/6) suppresses hepatitis B virus (HBV) ...the X protein (HBx), which redirects the cellular DNA damage-binding pro- tein 1 (DDB1)-containing E3 ... See full document
18
The Enigmatic X Gene of Hepatitis B Virus
... bind DNA, and its ability to activate transcription likely involves several different properties, in- cluding direct interaction with nuclear transcription compo- nents and activation of cytosolic signal ... See full document
10
Hepatitis B virus X protein represses miRNA 148a to enhance tumorigenesis
... in virus-related cancers; however, miRNA regula- tion of virus-related cancer development and progression remains poorly ...by hepatitis B virus (HBV) X protein (HBx) to ... See full document
17
Naringenin attenuates hepatitis B virus X protein induced hepatic steatosis
... the DNA-binding activity of the ...the DNA-binding activity of SREBP1, while Nar exposure yielded nominally dose-dependent decreases in this activity ... See full document
10
Enhancement of Hepatitis B Virus Replication by Its X Protein in Transgenic Mice
... genomic DNA as the standard, the homozygous wtTg05 mouse was found to carry two copies of the HBV genome and the wtTg08 mouse was found to carry six copies (data not ...and B, and a more detailed time-point ... See full document
6
Hepatitis B virus X protein is not central to the viral life cycle in vitro.
... Naturally occurring missense mutation in the Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest To exclude a pX-like contribution of HuH-7 hepatoma cells to viral gene exp[r] ... See full document
5
Enhancement of Hepatitis B Virus Replication by the Regulatory X Protein In Vitro and In Vivo
... capsid-associated DNA by Southern blot hybridization and densitometer ...HBV DNA measured in mice injected with ...viral DNA detected in the livers of mice injected with other plasmids ...viral ... See full document
7
In Silico Prediction and Docking of Tertiary Structure of Multifunctional Protein X of Hepatitis B Virus
... of protein provide (SCOP) collection of available protein structures and also augment them with the newer database like Protein Data Bank (PDB) ...for protein Structure ... See full document
12
Ground squirrel hepatitis virus DNA: molecular cloning and comparison with hepatitis B virus DNA.
... Thus, the two specific regions of HBV DNA used here as probes, one of which appears to contain the coding sequence for the major HBV surface antigen polypeptide and the other of which po[r] ... See full document
5
Distribution of Hepatitis B Virus Nuclear DNA
... HBV DNA under conditions mimicking antiviral ...nuclear DNA after cell division should have resulted in a much FIG 5 Dilution of HBV nuclear ...Hirt DNA from HepAD38 cells maintained under the ... See full document
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