[PDF] Top 20 Tyrosine phosphorylation in the human duodenum
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Tyrosine phosphorylation in the human duodenum
... These findings suggest that tyrosine kinase activity is not a significant factor in the regulation of crypt cell proliferation in the human duodenum either in normal subjects or in coeli[r] ... See full document
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Detection of a Tyrosine Phosphatase LAR on Intestinal Epithelial Cells and Intraepithelial Lymphocytes in the Human Duodenum
... of tyrosine phosphorylation in the human duodenum have indicated that proliferating cells in the middle portion of the duodenal crypt were devoid of this feature, suggesting that ... See full document
8
NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22
... MSU-treated human MM6 monocytic cells (Supplemental Figure 1B) and in ultraviolet light–treated (UV-treated) primary human keratino- cytes transfected with either control or PTPN22-targeting siRNA ... See full document
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Tyrosine Phosphorylation of the Tio Oncoprotein Is Essential for Transformation of Primary Human T Cells
... any phosphorylation signal, confirming that a tyrosine residue within the Flag epitope tag used for all Tio expression constructs is not ...Tio phosphorylation which was in- terpreted as an effect of ... See full document
7
Crystal induced neutrophil activation III Inflammatory microcrystals induce a distinct pattern of tyrosine phosphorylation in human neutrophils
... The tyrosine phosphorylation patterns induced by microcrystals differed from those stimulated by other soluble (FMLP, C5a, or leukotriene B4) or particulate (unopsonized latex beads or zymosan) agonists ... See full document
8
Crystal induced neutrophil activation IV Specific inhibition of tyrosine phosphorylation by colchicine
... The results obtained demonstrate a that colchicine specifically inhibits, at least in part through its action on microtubules, crystal-induced tyrosine phosphorylation in human neutrophi[r] ... See full document
9
Role of the tyrosine kinase pyk2 in the integrin dependent activation of human neutrophils by TNF
... primary human neutrophils; localize it to focal adhesions and podosomes; and demon- strate its tyrosine phosphorylation, activation, and association with paxillin during stimulation of adherent cells ... See full document
10
Tyrosine dephosphorylation of ASC modulates the activation of the NLRP3 and AIM2 inflammasomes
... ASC phosphorylation at Y144 was abrogated by ...where human and murine macrophages with concentrations of 1 µM and ...ASC tyrosine dephosphorylation is inhibited by PAO, we hypothesize that PAO acts ... See full document
10
Glucose induced phosphorylation of the insulin receptor Functional effects and characterization of phosphorylation sites
... the human insulin receptor have been identified as stoichiometrically the major phosphorylation sites in response to phorbol ester treat- ment (12, ...to phosphorylation at these sites, then removal ... See full document
9
Initiation of human myoblast differentiation via dephosphorylation of Kir2 1 K+ channels at tyrosine 242
... a tyrosine kinase inhibitor, genistein, and reduced by a tyrosine phosphatase inhibitor, ...a tyrosine phosphorylation is ...on human myoblast proliferation as the drugs were added to ... See full document
9
Gold nanoparticles induce heme oxygenase-1 expression through Nrf2 activation and Bach1 export in human vascular endothelial cells
... in human vascular endothelial cells ...its tyrosine phosphorylation ...export/tyrosine phosphorylation, leading to Nrf2 binding to the HO-1 E2 enhancer promoter region to drive HO-1 ... See full document
15
Human immunodeficiency virus matrix tyrosine phosphorylation: characterization of the kinase and its substrate requirements.
... of human immunodeficiency virus (HIV) matrix (MA) molecules is phos- phorylated on C-terminal ...MA tyrosine phosphor- ylation is accomplished by a cellular protein kinase which is incorporated into ...MA ... See full document
8
Activation of phospholipase C in human B cells is dependent on tyrosine phosphorylation
... on human lymphocytes, in addition to activation of PLC, increases tyrosine phosphorylation of specific ...of tyrosine kinase inhibitors which compete for substrate binding site of specific ... See full document
6
Phosphorylation of the Bovine Papillomavirus E2 Protein on Tyrosine Regulates Its Transcription and Replication Functions
... P apillomaviruses (PVs) are nonenveloped, double-stranded DNA viruses with circular genomes of ⬃ 8 kb. This compact genome harbors 8 major genes, including 6 early genes (E1, E2, E4, E5, E6, and E7) and 2 late genes (L1 ... See full document
15
Src drives the Warburg effect and therapy resistance by inactivating pyruvate dehydrogenase through tyrosine-289 phosphorylation
... by phosphorylation of three specific serine residues on pyruvate dehydrogenase (PDH), the first and most important enzyme component of PDC ...Such phosphorylation is catalyzed by pyruvate dehydrogenase ... See full document
12
Proteomic analysis of tyrosine phosphorylation during human liver transplantation
... Protein phosphorylation is considered to be one of the major determinants regulating a large spectrum of biolog- ical processes ...and tyrosine residues, by acting as a switch to turn "on" or ... See full document
15
Antiviral chemotherapy facilitates control of poxvirus infections through inhibition of cellular signal transduction
... of human epithelial cells, a series of in vitro experiments was ...of human fibroblasts with various concentrations of recombinant SPGF produced and purified as detailed elsewhere (8), the number of cells ... See full document
10
The role of the phosphatidylinositol transfer protein and the small GTP-ASE ARF in regulated exocytosis from RBL-2H3 mast cells
... FcsR1 tyrosine-phosphorylation was unaffected, however PLC activity and serotonin release were both ...the phosphorylation of a number of receptor-associated proteins, PLCy1 and y2 (49,50), the 85kDa ... See full document
195
Original Article Baicalein suppresses EGF-induced proliferation and migration of glioma cells via EGFR/Akt signaling pathways
... on human health and treat- ...Bad phosphorylation in vivo and in baicalein-treated xenograft ...of human cancer cells by inducing autophagic cell death in human pros- tate and breast cancer ... See full document
12
Paxillin is an intrinsic negative regulator of platelet activation in mice
... whereas human platelets only express Hic-5 ...In human platelets, which only express Hic-5, it will be necessary to elucidate whether Hic-5 acts as a positive regulator of integrin αIIbβ3 ... See full document
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