[PDF] Top 20 URI 1 is required for DNA stability in C elegans
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URI 1 is required for DNA stability in C elegans
... The uri gene (unconventional prefoldin RPB5 interactor) was first identified in human cells where URI was found to be part of a multi- protein ...that URI is phosphorylated in a TOR-dependent manner ... See full document
9
Alpi, Arno (2004): DNA damage checkpoint pathways and the maintenance of genome stability in C. elegans. Dissertation, LMU München: Fakultät für Biologie
... how DNA damage can be ...for DNA damage sensors because they interact with DNA and they are essential for the activation of the DNA damage response pathways (reviewed in (O'Connell et ... See full document
154
TRPM channels are required for rhythmicity in the ultradian defecation rhythm of C. elegans
... and gtl-1 compromises the ability of the oscillator to adhere to the input period. This is clearly the case to some extent as genes such as clk-1 change the mean of the cycle without destabilising the ... See full document
11
The C elegans homolog of nucleoporin Nup98 is required for the integrity and function of germline P granules
... C. elegans JH1999 hermaphrodites (GFP::Histone H2B::nos-2 3⬘UTR) were treated with the indicated RNAi for 22 hours and their embryos co-stained for PGL-1, GFP and ... See full document
10
Protection offered by Resveratrol against Acrylamide induced Genotoxicity in C elegans
... phase 1 metabolism and allow for subsequent detoxification in phase ...phase 1 enzymes and comprise a superfamily of heme-containing monoxygenases (Menzel et ...in C. elegans exposed to 500 ... See full document
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Components of the transcriptional Mediator complex are required for asymmetric cell division in C elegans
... In every organism, asymmetric cell divisions are crucial to the generation of cell diversity (Hawkins and Garriga, 1998; Horvitz and Herskowitz, 1992). In Drosophila, asymmetric divisions of neuroblasts cause the ... See full document
9
PAR 3 is required for epithelial cell polarity in the distal spermatheca of C elegans
... A comparison of par-3(RNAi) and control worms revealed a slightly reduced growth rate in the treated individuals. On average, the treated worms molted into adults 2-3 hours later than controls. This difference is within ... See full document
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The folic acid metabolism gene mel 32/Shmt is required for normal cell cycle lengths in Caenorhabditis elegans
... human DNA and chromosome breakage: impli- cations for cancer and neuronal ...Caenorhabditis elegans. Genetics 77: 71-94. CABREIRO F, AU C, LEUNG KY, VERGARA-IRIGARAY N, COCHEME HM, NOORI T, WEINKOVE ... See full document
6
CDC 25 1 stability is regulated by distinct domains to restrict cell division during embryogenesis in C elegans
... in C. elegans, two ...is required for the timely degradation of ...its stability and turnover, in order to ensure the timely divisions of intestinal cells and coordinate them with the ... See full document
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Homologous Recombination Is Required for Genome Stability in the Absence of DOG-1 in Caenorhabditis elegans
... The C. elegans p53 ortholog, cep-1, and deletions in the dog-1 background: In ...C. elegans, as in mammals, CEP- 1/p53 is required for DNA-damage-induced ... See full document
12
The Oxidative Stress Response in Caenorhabditis elegans Requires the GATA Transcription Factor ELT-3 and SKN-1/Nrf2
... 2015). C. elegans lacks a Keap1 ortholog; however, the C. elegans protein WDR-23 (which interacts with the CUL-4/DDB-1 complex) acts analogously by target- ing SKN-1 for ... See full document
14
The GAPs, GEFs, and GDIs of heterotrimeric G-protein alpha subunits
... the C. elegans RIC-8 protein can act as a GEF for the nematode Gα subunits GOA-1 or ...or C. elegans RIC-8 can act as a GEF for GoLoco-bound Gα·GDP ...to C. elegans and ... See full document
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The 60-Residue C-Terminal Region of the Single-Stranded DNA Binding Protein of Herpes Simplex Virus Type 1 Is Required for Cooperative DNA Binding
... The C-terminal deletion mutant was derived from Bac29 by substitution of the SalI-HindIII fragment with a PCR product containing a deletion of nucleotides 3409 to 3591 and generated using the primers ... See full document
11
Signaling by the Engulfment Receptor Draper: A Screen in Drosophila melanogaster Implicates Cytoskeletal Regulators, Jun N-Terminal Kinase, and Yorkie
... Caenorhabditis elegans, is a cell-surface receptor required for the recognition and engulfment of apoptotic cells, glial clearance of axon fragments and dendritic pruning, and salivary gland ... See full document
18
MIB-1 Is Required for Spermatogenesis and Facilitates LIN-12 and GLP-1 Activity in Caenorhabditis elegans
... is required for secretory cells to differentiate normally and avoid transitioning to a pre- cancerous state (Capoccia et ...kinase 1, resulting in the phosphorylation and activation of interferon regulatory ... See full document
21
gld-1, a tumor suppressor gene required for oocyte development in Caenorhabditis elegans.
... Thus, in both sexes, class D alleles disrupt the decision of germ cells to adopt the male fate but have no effect on other germline processes (oogenesis, progression throu[r] ... See full document
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PAR 6 is required for junction formation but not apicobasal polarization in C elegans embryonic epithelial cells
... DLG- 1/Discs large, and AJM-1 in par-6(M/Z) ...HMP- 1 and HMR-1 fragmentation was often less severe than DLG-1 or AJM-1 ...also required to form continuous apical ... See full document
10
THE DNA OF CAENORHABDITIS ELEGANS
... Adult nematodes obtained from liquid cultures contain about fifteen times more DNA than do larvae. The growth of the gonad and the number of develop- ing embryos is sufficie[r] ... See full document
10
<p>c-Src is required for hypoxia-induced metastasis-associated functions in prostate cancer cells</p>
... Figure 1 SFKs are activated in prostate cancer. (A) Gene expression of SRC, FYN and LYN and overall survival curve in prostate cancer patients analyzed by TCGA data- mining. Kaplan-Meier method and log-rank test ... See full document
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The mog-1 gene is required for the switch from spermatogenesis to oogenesis in Caenorhabditis elegans.
... By contrast, animals homo- zygous for any of six loss-of-function mutations in the gene mog-1 (for masculinization of the germ line) make sperm continuously and do n[r] ... See full document
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