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WE HAVE previously shown that the

WE HAVE previously shown that the

... 1 ' 3 While abnormal electrical activity demar- cated the outermost limits of measurable dys- function, distinction of the borders of ischemic areas from the centers required simultaneou[r] ... See full document

12

Divergence of male courtship displays between sympatric forms of anadromous threespine stickleback

Divergence of male courtship displays between sympatric forms of anadromous threespine stickleback

... sympatry. We have previously shown that males of the Pacific Ocean lineage perform the zig-zag dance, while sympatric males of the Japan Sea lineage perform a different dance, which we ... See full document

19

Cosuppression of I Transposon Activity in Drosophila by I-Containing Sense and Antisense Transgenes

Cosuppression of I Transposon Activity in Drosophila by I-Containing Sense and Antisense Transgenes

... genesis (Picard and L’He´ritier 1971; reviewed in Yet, the refined molecular mechanisms involved in Bre´gliano et al. 1980; Bre´gliano and Kidwell 1983; cosuppression are still poorly understood, despite exten- Finnegan ... See full document

8

Circannual basis of geographically distinct bird schedules

Circannual basis of geographically distinct bird schedules

... conditions. We have previously shown that stonechats of European, Siberian and African origin differed conspicuously in the timing of postjuvenile moult and migratory restlessness and in the ... See full document

11

Hepatic JAK2 protects against atherosclerosis through circulating IGF-1

Hepatic JAK2 protects against atherosclerosis through circulating IGF-1

... others have previously shown that JAK2 is required for growth hormone (GH) signaling in the liver, such that hepatic Jak2–deficient mice have significantly reduced levels of circulating IGF-1 ... See full document

18

Immune escape by human immunodeficiency virus type 1 from neutralizing antibodies: evidence for multiple pathways.

Immune escape by human immunodeficiency virus type 1 from neutralizing antibodies: evidence for multiple pathways.

... We have previously shown that neutralization resistance of an escape mutant with an amino acid substitution in the transmembrane protein A582T occurs because of alteration of a conformat[r] ... See full document

8

Restoration of LDL receptor function in cells from patients with autosomal recessive hypercholesterolemia by retroviral expression of ARH1

Restoration of LDL receptor function in cells from patients with autosomal recessive hypercholesterolemia by retroviral expression of ARH1

... cells. We have previously shown that EBV-lymphocytes from the probands in families 1 and 2 are unable to take up and degrade LDL ...(2). We have recently obtained an explant from ... See full document

9

Tacaribe arenavirus RNA synthesis in vitro is primer dependent and suggests an unusual model for the initiation of genome replication.

Tacaribe arenavirus RNA synthesis in vitro is primer dependent and suggests an unusual model for the initiation of genome replication.

... We have previously shown that in vivo, the viral mRNAs are predominantly found in the pellet fraction and the genomes and antigenomes are predominantly found in the CsCl band fraction of[r] ... See full document

7

Hordein polypeptide pattern in relation to malting quality and the varietal identification of malted barley-grain

Hordein polypeptide pattern in relation to malting quality and the varietal identification of malted barley-grain

... We have previously shown the presence of different seed types, or biotypes, in a number of varieties and have shown that this variation exists in seed and plants checked for morphologica[r] ... See full document

5

The intrinsic stiffness of human trabecular meshwork cells increases with senescence

The intrinsic stiffness of human trabecular meshwork cells increases with senescence

... has shown that the HTM in glaucoma is ~20 fold stiffer [12], and available data suggests this is due to changes in both cytoskeletal dynamics and extracellular matrix ...as we have previously ... See full document

13

A novel octopamine receptor with preferential expression in <i>Drosophila</i> mushroom bodies

A novel octopamine receptor with preferential expression in <i>Drosophila</i> mushroom bodies

... because we have previously shown that the novel dopamine receptor DAMB is localized preferentially to the mushroom body lobes and pedun- culi (Han et ... See full document

9

IKBKB founder mutation). We have previously

IKBKB founder mutation). We have previously

... PID, we have previously shown that it will not identify the majority of T-cell positive forms of SCID and PID that are prevalent in our ...programme we hope to implement in the coming ... See full document

9

Inflammation and chronic colonization of &lt;em&gt;Haemophilus influenzae&lt;/em&gt; in sputum in COPD patients related to the degree of emphysema and bronchiectasis in high-resolution computed tomography

Inflammation and chronic colonization of <em>Haemophilus influenzae</em> in sputum in COPD patients related to the degree of emphysema and bronchiectasis in high-resolution computed tomography

... exacerbations. We have previously shown that chronic colonization of Haemophilus influenzae during stable disease is related to increased inflammation, and we now aimed to relate ... See full document

9

Neuronal eotaxin and the effects of ccr3 antagonist on airway hyperreactivity and M2 receptor dysfunction

Neuronal eotaxin and the effects of ccr3 antagonist on airway hyperreactivity and M2 receptor dysfunction

... The role of eosinophils as effector cells in asthma has been debated in recent years. A study in patients with asthma exam- ined the effects of neutralizing IL-5 with a humanized monoclonal antibody and suggested that ... See full document

10

Homothorax and Extradenticle alter the transcription factor network in Drosophila ommatidia at the dorsal rim of the retina

Homothorax and Extradenticle alter the transcription factor network in Drosophila ommatidia at the dorsal rim of the retina

... 2012). We described two factors that are required for Hth/Exd function and therefore might directly interact with ...them. We show that Otd is required for the activation of rh3 expression in the DRA, ... See full document

11

‘We may be children, but we all have rights’

‘We may be children, but we all have rights’

... The children and young people also expressed concern about nothing being done when they complain, even when their complaint is taken seriously. They are also nervous about possible negative repercussions and are acutely ... See full document

17

‘We may be children, but we all have rights’

‘We may be children, but we all have rights’

... would have the option of raising the complaint with her local education authority, she may also want to pursue a complaint against her individual teacher with the ... See full document

90

Neoadjuvant Endocrine Therapy in Breast Cancer Upregulates the Cytotoxic Drug Pump ABCG2/BCRP, and May Lead to Resistance to Subsequent Chemotherapy

Neoadjuvant Endocrine Therapy in Breast Cancer Upregulates the Cytotoxic Drug Pump ABCG2/BCRP, and May Lead to Resistance to Subsequent Chemotherapy

... Ethical approval for use of patient samples and anonymised data and for the consent process used was obtained from Leeds (East) Research Ethics Committee (reference 06/Q1206/180). Informed consent was obtained when ... See full document

19

ARDS following oesophagectomy: a comparison of two trials

ARDS following oesophagectomy: a comparison of two trials

... may be that dihydropyridine use is a marker of worse systemic disease and therefore perioperative risk, although we did not find an association with aspirin, beta-blockers or statins. It would be premature to ... See full document

5

Glycolysis, Glutaminolysis, and Fatty Acid Synthesis Are Required for Distinct Stages of Kaposi&#039;s Sarcoma-Associated Herpesvirus Lytic Replication

Glycolysis, Glutaminolysis, and Fatty Acid Synthesis Are Required for Distinct Stages of Kaposi's Sarcoma-Associated Herpesvirus Lytic Replication

... Glycolysis is required for early and late gene expression. To determine at what stage inhibition of glycolysis blocks viral replication, we examined early and late KSHV gene expression upon oxamate treatment of ... See full document

15

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