• No results found

ABSOLUTE CONTRAINDICATIONS FOR EXERCISE Depending on any other co-morbidities, absolute

In document Exercise Prescription - eBook (Page 119-124)

Exercise and diet

ABSOLUTE CONTRAINDICATIONS FOR EXERCISE Depending on any other co-morbidities, absolute

contra-indications for exercise will be as for those cited for other individuals (Appendix A, Table A.1).

Suggested reading

SUMMARY

Obesity is now recognized as a disease in its own right and can increase risk of:

type II diabetes cardiovascular disease several types of cancer gallbladder disease musculoskeletal disorders respiratory problems.

Despite obesity having strong genetic determinants, the principal causes of the rise in obesity are seden-tary lifestyles and high-fat and energy-dense diets.

Overweight/obesity is a complex issue and factors that contribute are hormones, drugs, illness, environ-mental and psychological issues.

Active obese individuals show lower morbidity and mortality rates than normal weight sedentary indivi-duals. Therefore, being physically fit and overweight may be less risky to health than being slim and unfit.

Realistic weight loss goals should be set at around 0.25 kg to 0.5 kg and should be considered part of a lifestyle change.

Physical activity/exercise intervention should commence with light PA/exercise.

Increases in any lifestyle physical activity should be greatly encouraged.

To maximize energy expenditure, interval and longer bouts of PA/exercise are effective. Accumu-lative shorter bouts may be a suitable alternative.

A programme that integrates both aerobic and resis-tance PA/exercise is most effective at maintaining FFM and metabolic rate.

Habitual appropriate PA/exercise intervention can result in:

modification of associated disorders, such as coronary heart disease, diabetes and insulin resis-tance, blood lipids and blood pressure.

↓ rates of morbidity and mortality

↑ aerobic fitness

↓ body fat

maintenance of FFM

↑ RMR and energy expenditure enhanced insulin sensitivity assistance in weight management.

Co-morbidities and factors such as breathlessness and mobility should be considered within the PA/exercise programme.

Suggested readings

Groer M W, Shekleton M E 1989 Basic pathophysiology: a holistic approach, 3rd edn. Mosby, St Louis

Vander A J, Sherman J H, Luciano D S 1990 Human physiology.

McGraw-Hill, New York

References and bibliography

Andersen R E 1996 Physiology of obesity. In: Cotton R T (ed) Lifestyle and weight management consultant manual. American Council for Exercise, San Diego, p 95–118

Andersen R E 1999 Exercise, an active lifestyle, and obesity. The Physician and Sports Medicine 27(10):41–42

Andersen R E, Wadden T A, Bartlett S J et al 1999 Effects of lifestyle activity versus structured aerobic exercise in obese women: a randomised trial. Journal of the American Medical Association 281(4):335–340

Anderson D M, Keith J, Novak P D et al (eds) 2002 Mosby’s medical, nursing and allied health dictionary, 6th edn. Mosby, St Louis Astrup A 2001 Healthy lifestyles in Europe: prevention of obesity and

type II diabetes by diet and physical activity. Public Health Nutrition 4(2B):499–515

Axen K V, Dikeakos A, Sclafani A 2003 High dietary fat promotes syndrome X in nonobese rats. Journal of Nutrition 133(7):2244–2249

Babb T G, DeLorey D S, Wyrick B L et al 2002 Mild obesity does not limit change in end-expiratory lung volume during cycling in young women. Journal of Applied Physiology 92(6):2483–2490 Ballor D L, Poehlman E T 1995 A meta-analysis of the effects of exercise

and diet restriction on resting metabolic rate. European Journal of Applied Physiology 71(6):535–542

Bandini L G, Schoeller D A, Cyr H N et al 1990 Validity of reported energy intake in obese and nonobese adolescents. American Journal of Clinical Nutrition 52(3):421–425

Banz W J, Maher M A, Thompson W G et al 2003 Effects of resistance versus aerobic training on coronary artery disease risk factors.

Experimental Biology and Medicine 228(4):434–440

Barash G S, Farooqi S, O’Rahilly S 2000 Genetics of body-weight regulation. Nature 404:644–651

Bianchini F, Kaaks R, Vainio H 2002 Weight control and physical activity in cancer prevention. Obesity Reviews 3(1):5–8

Bjorntorp P A 1989 Sex differences in the regulation of energy balance with exercise. American Journal of Clinical Nutrition 17:55–65 Blair S N, Brodney S 1999 Effects of physical activity and obesity on

morbidity and mortality: current evidence and research issues.

Medicine and Science in Sports and Exercise 31(11 suppl): S646–S662 Boreder C E, Brenner M, Hofman Z et al 1991 The metabolic

consequences of low and moderate intensity exercise with or without feeding in lean and borderline obese males. International Journal of Obesity 15(2):95–104

Brownell K D 1995 Exercise in the treatment of obesity. In: Brownell K D, Fairburn C G (eds) Eating disorders and obesity: a

comprehensive handbook. Guilford Press, New York, p 473–478 Byrne H K, Wilmore J H 2001 The effects of a 20-week exercise training

program on resting metabolic rate in previously sedentary, moderately obese women. International Journal of Sport Nutrition and Exercise Metabolism 11(1):15–31

Campbell P, Dhand R 2000 Obesity. Nature 404:631

Cavallo E, Armellini F, Zamboni M et al 1990 Resting metabolic rate, body composition and thyroid hormones. Short term effects of very low calorie diet. Hormone and Metabolic Research 22(12):632–635 CDC (Centers for Disease Control) 2003 Defining overweight and

obesity. Online. Available:

http://www.cdc.gov/bccdogo/dnpa/obesity/defining.htm February 2004

CDP (Chronic Disease Prevention) 2003 Preventing obesity and chronic

disease through good nutrition and physical activity. Online.

Available: http://www.cdc.gov/nccdphp February 2004 Chandrasekharan N 1999 Changing concepts in lipid nutrition in

health and disease. Medical Journal of Malaysia 54(3):408–427 Chen G, Koyama K, Yuan X et al 1996 Disappearance of body fat in

normal rats induced by adenovirus-mediated leptin gene therapy.

Proceedings of the National Academy of Science USA 93:14795–14799

Chin S, Apriletti J, Gick G 1998 Characterization of a negative thyroid hormone response element in the rat sodium, potassium-adenosine triphosphataseα3 gene promoter. Endocrinology 139(8):3423–3431 Coleman K J, Raynor H R, Mueller D M et al 1999 Providing sedentary

adults with choices for meeting their walking goals. Preventive Medicine 28:510–519

Dale J, Daykin J, Holder R et al 2001 Weight gain following treatment of hyperthyroidism. Clinical Endocrinology 55(2):233–239 Dixon J B, Dixon M E, O’Brien PE 2003 Depression in association with

severe obesity: changes with weight loss. Archives of Internal Medicine 163(17):2058–2065

Ebisu T I 1985 Splitting the distance of endurance running: effect on cardiovascular endurance and blood lipids. Japanese Journal of Physical Education 30/31:37–43

El-Hazmi M A F, Warsy A S 1997 Prevalence of obesity in the Saudi population. Annals of Saudi Medicine 17(3):302–306

Felson D T, Anderson J J, Naimark A et al 1988 Obesity and knee osteoarthritis. The Framingham study. Annals of Internal Medicine 109(1):18–24

Fiebig R G, Hollander J M, Ney D et al 2002 Training down-regulates fatty acid synthase and body fat in obese Zucker rats. Medicine and Science in Sports and Exercise 34(7):1106–1114

Golan R 1993 Effects of thymopentin on the responses of hypothalamic-pituitary-adrenal axis to a high intensity dynamic exercise protocol.

Microform Publications for Sport and Human Performance, Eugene, OR

Golay A, Hagon I, Painot D et al 1997 Personalities and alimentary behaviours in obese patients. Patient Education and Counselling 31(2):103–112

Goodpaster B H, Katsiaras A, Kelly D E 2003 Enhanced fat oxidation through physical activity is associated with improved insulin sensitivity in obesity. Diabetes 52(9):2101–2197

Goran M I 2000 Energy metabolism and obesity. Medical Clinics in North America 84(2):347–362

Groer M W, Shekleton M E 1989 Basic pathophysiology: a holistic approach, 3rd edn. Mosby, St Louis

Hainer V, Kunesova M, Parizkova J et al 1997 Health risks and economic costs associated with obesity requiring a comprehensive weight reduction program. Casopis Lekaru Ceskych 136(12):367–372 Haynes G R, Heshka J, Chadee K et al 2003 Effects of dietary fat type

and energy restriction on adipose tissue fatty acid composition and leptin production in rats. Journal of Lipid Research 44(5):893–901 Hensrud DD 2004 Diet and obesity. Current Opinion in

Gastroenterology 20(2):119–124

Hickey M S, Calsbeek D J 2001 Plasma leptin and exercise: recent findings. Sports Medicine 31(8):583–589

Hill J O, Trowbridge F L 1998 Childhood obesity: future directions and research priorities. Paediatrics 101(3 Pt 2):570–574

Hill R J, Davies P S 2001 The validity of self-reported energy intake as determined using the doubly labelled water technique. British Journal of Nutrition 85(4):415–430

Hulens M, Vansant G, Lysens R et al 2001 Exercise capacity in lean versus obese women. Scandinavian Journal of Medicine and Science in Sports 11(5):305–309

Huskey R J 1998 How’s your BMI (body mass index)? Online. Available http://www.people.virginia.edu/~rjh9u/bmi.html February 2003 Idzior-Walus B, Mattock M B, Solnica B et al 2001 Factors associated

Suggested Readings, References and Bibliography 109

Suggested readings, references and bibliography

with plasma lipids and lipoproteins in type I diabetes mellitus: the EURODIAB IDDM Complications Study. Diabetic Medicine 18(10):786–796

Ikemoto S, Takahashi M, Tsunoda N et al 1996 High-fat diet-induced hyperglycemia and obesity in mice: differential effects of dietary oils. Metabolism: Clinical and Experimental 45(12):1539–1546 Jakicic J M, Wing R R, Butler B A et al 1995 Prescribing exercise in

multiple short bouts versus one continuous bout: effects on adherence, cardiorespiratory fitness and weight loss in overweight women. International Journal of Obesity 19:893–901

Jensen J, Bysted A, Dawids S et al 1999 The effect of palm oil, lard, and puff-pastry margarine on postprandial lipid and hormone responses in normal-weight and obese young women. British Journal of Nutrition 82(6):469–479

Jequier E, Bray G A 2002 Low-fat diets are preferred. American Journal of Medicine 113(suppl)9B:41S–46S

Jorm A F, Korten A E, Christensen H et al 2003 Association of obesity with anxiety, depression and emotional well-being: a community survey. Australian and New Zealand Journal of Public Health 27(4):434–440

Josling L 2000 Obesity: a curable epidemic. Online. Available:

http://www.wsws.org/articles August 2001

Katzmarzyk P T, Jassen I, Ardern C I 2003 Physical inactivity, excess adiposity and premature mortality. Obesity Reviews 4(4):257–290 Kautzky-Willer A, Ludwig C, Nowotny P et al 1999 Elevation of

plasma leptin concentrations in obese hyperinsulinaemic hypothyroidism before and after treatment. European Journal of Clinical Investigation 29(5):395–403

Kayman S, Bruvdd W, Stern J S 1990 Maintenance and relapse after weight loss in women: behavioural aspects. American Journal of Clinical Nutrition 52(5):800–807

Kelley D E, Goodpaster B H 1999 Effects of physical activity on insulin action and glucose tolerance in obesity. Medicine and Science in Sports and Exercise 31(11 suppl):S619–S623

Kempen K P, Saris W H, Kuipers H et al 1998 Skeletal muscle metabolic characteristics before and after energy restriction in human obesity:

fibre type, enzymatic beta-oxidation capacity and fatty acid-binding protein content. European Journal of Clinical Investigation 28(12):1030–1037

Key T J, Appleby P N, Reeves G K et al 2003 Body mass index, serum sex hormones, and breast cancer risk in postmenopausal women.

Journal of the National Cancer Institute 95(16):1218–1226 Kiess W, Galler A, Reich A et al 2001 Clinical aspects of obesity in

childhood and adolescence. Obesity Reviews 2(1):29–36

King A C, Tribble D L 1991 The role of exercise in weight regulation in nonathletes. Sports Medicine 11(5):331–349

Kiortsis D N, Durack I, Turpin G 1999 Effects of low-calorie diet on resting metabolic rate and serum tri-iodothyronine levels in obese children. European Journal of Pediatrics 158(6):446–450

Klesges R C, Eck L H, Ray J W 1995 Who underreports dietary intake in a dietary recall? Evidence from the Second National Health and Nutrition Examination Survey. Journal of Consulting and Clinical Psychology 63(3):438–444

Koenig S M 2001 Pulmonary complications of obesity. American Journal of the Medical Sciences 321(4):249–279

Kopp W 2003 High-insulinogenic nutrition – an etiologic factor for obesity and the metabolic syndrome? Metabolism: Clinical and Experimental 52(7):840–844

Kriketos A D, Sharp T A, Seagle H M et al 2000 Effects of aerobic fitness on fat oxidation and body fatness. Medicine and Science in Sports and Exercise 32(4):805–811

Laakso M, Suhonen M, Julkunen R et al 1990 Plasma insulin, serum lipids and lipoproteins in gall stone disease in non-insulin dependent diabetic subjects: a case control study. Comment in Gut 32(2):339–340 Lean M E 2000 Review, Pathophysiology of obesity. Proceedings of the

Nutrition Society 59(3):331–336

Lee C D, Blair S N, Jackson A S 1999 Cardiorespiratory fitness, body

composition, and all-cause and cardiovascular disease mortality in men. American Journal of Clinical Nutrition 69(3):373–380 Lewis G F, Carpentier A, Adeli K et al 2002 Disordered fat storage and

mobilization in the pathogenesis of insulin resistance and type 2 diabetes. Endocrine Reviews 23(2):201–229

Li J, Li S, Feuers R J et al 2001 Influence of body fat distribution on oxygen uptake and pulmonary performance in morbidly obese females during exercise. Respiration 6(1):9–13

Lin M H, Tuig J G, Romsos D R et al 1980 Heat production and Na+-K+ ATPase enzyme units in lean and obese (ob/ob) mice. American Journal of Physiology 238:E193–E199

Ljung T, Ottosson M, Ahlberg A C et al 2002 Central and peripheral glucocorticoid receptor function in abdominal obesity. Journal of Endocrine Investigation 25(3):229–235

Long S J, Hart K, Morgan L M 2002 The ability of habitual exercise to influence appetite and food intake in response to high- and low-energy preloads in man. British Journal of Nutrition 87(5):517–523 Mayer J, Bullen B A 1974 Nutrition, weight control and exercise. In:

Johnson W R, Buskirk E R (eds) Science and medicine of exercise and sport. Harper & Row, New York

Mehrotra C, Chundy N, Thomas V 2003 Obesity and physical inactivity among Wisconsin adults with arthritis. Wisconsin Medical Journal 102(7):24–28

Mehta S, Mathur D, Chaturvedi M et al 2001 Thyroid hormone profile in obese subjects: a clinical study. Journal of the Indian Medical Association 99(5):260–261

Melby C, Schroll C, Edwards G et al 1993 Effect of acute resistance exercise on post exercise energy expenditure and resting metabolic rate. Journal of Applied Physiology 75(4):1847–1853

Melton C A 1994 The effect of exercise intensity on excess post-exercise oxygen consumption (EPOC) in normal and fat obese women.

Microform Publications for Sport and Human Performance, Eugene, OR

Misra A, Arora N, Mondal S et al 2001 Relation between plasma leptin and anthropometric and metabolic covariates in lean and obese diabetic and hyperlipidaemic Asian Northern Indian subjects.

Diabetes, Nutrition and Metabolism – Clinical and Experimental 14(1):18–26

NHANES (National Health and Nutrition Examination Survey) 2002 National Health and Nutrition Examination Survey. Department of Health and Human Services, US

Nieman L K 2002 Diagnostic tests for Cushing’s syndrome. Annals of the New York Academy of Science 970:112–118

NIH (National Institutes for Health) 2003 Prescription medications for the treatment of obesity. Online. Available: http://www.niddk.nih.gov/

health/nutrit/pubs/presmeds.htm March 2004

Onyike C U, Crum R M, Lee H B et al 2003 Is obesity associated with major depression? Results from the Third National Health and Nutrition Examination Survey. American Journal of Epidemiology 158(12):1139–1147

Park S K, Park J H, Kwon Y C et al 2003 The effect of combined aerobic and resistance exercise training on abdominal fat in obese middle-aged women. Journal of Physiological Anthropology and Applied Human Science 22(3):129–135

Pate R R, Pratt M, Blair S N et al 1995 Physical activity and public health: A recommendation from the Centers of Disease Control and Prevention and the American College of Sports Medicine. Journal of the American Medical Association 273:402–407

Peters J C 2003 Dietary fat and body weight control. Lipids 38(2):123–127

Phillips G B, Jing T, Heymsfield S B 2003 Relationships in men of sex hormones, insulin, adiposity, and risk factors for myocardial infarction. Metabolism: Clinical and Experimental 52(6):784–790 Pihl E, Jurimae T 2001 Cardiovascular disease risk factors in males with

normal body weight and high waist-to-hip ratio. Journal of Cardiovascular Risk 8(5):299–305

Pijl H, Meinders A E 1996 Bodyweight change as an adverse effect of

drug treatment. Mechanisms and management. Drug Safety 14(5):329–342

Pinkney J H, Goodrick S J, Katz J et al 1998 Leptin and the pituitary-thyroid axis: a comparative study in lean, obese, hypopituitary-thyroid and hyperthyroid subjects. Clinical Endocrinology 49(5):583–588 Poehlman E T 1989 Exercise and its influence on resting energy

metabolism in man. Medicine and Science in Sports and Exercise 21(5):515–525

Poehlman E T, Toth M J, Bunyard L B et al 1995 Physiological predictors of increasing total and central adiposity in aging men and women. Archives of Internal Medicine 155(22):2443–2448 Poehlman E T, Toth M J, Ades P A et al 1997 Gender differences

in resting metabolic rate and noradrenaline kinetics in older individuals. European Journal of Clinical Investigation 27(1):23–28

Poirier P, Despres J P 2001 Exercise in weight management of obesity.

Cardiology Clinics 19(3):459–470

Prentice A M, Jebb S A 1995 Obesity in Britain: glutton or sloth? British Medical Journal 311(7002):437–439

Ramachandran A, Snehalatha C, Satyayani K et al 2000 Cosegregation of obesity with familial aggregation of type 2 diabetes mellitus.

Diabetes, Obesity and Metabolism 2(3)129–154

Ravussin E, Bogardus C 2000 Energy balance and weight regulation:

genetics versus environment. British Journal of Nutrition 83(suppl)1:S17–S20

Romsos D 1981 Efficiency of energy retention in genetically obese animals and in dietary-induced thermogenesis. Federation Proceedings 40(10):2524–2529

Ross R, Janssen I 1999 Is abdominal fat preferentially reduced in response to exercise-induced weight loss? Medicine and Science in Sports and Exercise 31(11) (suppl 1):S568–S572

Samaras K, Kelly P, Chiano M N et al 1999 Genetic and environmental influences in total-body and central abdominal fat: the effect of physical activity in female twins. Annals of Internal Medicine 130(11):873–882

Schoeller D A, Bandini L G, Dietz W H 1990 Inaccuracies in self-reporting intake identified by comparison with the doubly labelled water method. Canadian Journal of Physiology and Pharmacology 68(7):941–949

Seo C 1996 Effects of ethanol on thermoregulation response during cold air exposure in male and female subjects. Microform Publications for Sport and Human Performance, Eugene, OR

Shafrir E, Ziv E 1998 Cellular mechanism of nutritionally induced insulin resistance: the desert rodent Psammomys obesus and other animals in which insulin resistance leads to detrimental outcome.

Journal of Basic and Clinical Physiology and Pharmacology 9(2–4):347–385

Shah M, Miller D S, Geisslier C A 1988 Lower metabolic rates in post-obese versus lean women: thermogenesis, basal metabolic rate and genetics. European Journal of Clinical Nutrition 42(9):741–752 Shephard R J 1989 Nutritional benefits of exercise. Journal of Sports

Medicine and Physical Fitness 29(1):83–90

Sjodin A M, Forslund A H, Westerterp K R et al 1996 The influence of physical activity and BMR. Medicine and Science in Sports and Exercise 28(1):85–91

Sjostrom L, Rissanen A, Andersen T et al 1998 Randomised placebo-controlled trial of orlistat for weight loss and prevention of weight regain in obese patients. European multicentre orlistat study group.

Lancet 352:167–172

Slentz C, Duscha B D, Johnson J L et al 2004 Effects of the amount of exercise on body weight, body composition and measures of central obesity: STRRIDE – a randomised controlled study. Archives of Internal Medicine 164(1):31–39

Sone M, Osamura R Y 2001 Leptin and the pituitary. Pituitary 4(1–2):15–23

Speakman J R, Selman C 2003 Physical activity and resting metabolic

rate. Proceedings of the Nutrition Society 62(3):621–634 Stevens J, Cai J, Evenson K R et al 2002 Fitness and fatness as

predictors of mortality from all causes and from cardiovascular disease in men and women in the lipid research clinics study.

American Journal of Epidemiology 156(9):832–841

Sweeney G, Klip A 2001 Mechanisms and consequences of Na+-K+ -pump regulation by insulin and leptin. Cellular and Molecular Biology 47(2):363–372

Toth M J, Beckett T, Poehlman E T 1999 Physical activity and the progressive change in body composition with aging: current evidence and research issues. Medicine and Science in Sports and Exercise 31(11):S590

Tsofliou F I, Pitsiladis Y P, Malkova D I et al 2003 Moderate physical activity permits acute coupling between serum leptin and appetite-satiety measures in obese women. International Journal of Obesity 27(11):1332–1339

Ukkola O, Joanisse D R, Tremblay A et al 2003 Na+K+-ATPase alpha 2-gene and skeletal muscle characteristics in response to long-term overfeeding. Journal of Applied Physiology 94(5):1870–1874 US Surgeon General 2001 Call to action to prevent overweight and

obesity, 2001. Online. Available:

http://www.cdc/nccdphp/dnpa/obesity/contributing_factors.htm February 2004

Vague J 1947 La différenciation sexuelle, facteur determinant des formes de l’obésité. Presse Med 30:339–340

van Baak M A 1999 Physical activity and energy balance. Public Health Nutrition 2(3A):335–339

Vander A J, Sherman J H, Luciano D S 1990 Human physiology.

McGraw-Hill, New York

van Marken Litchenbelt W D, Daanen H A 2003 Cold-induced metabolism. Current Opinion in Clinical Nutrition and Metabolic Care 6(4):469–475

van Mil E G, Westerterp K R, Gerver W J et al 2001 Body composition in Prader–Willi syndrome compared with nonsyndromal obesity:

relationship to physical activity and growth hormone. Journal of Pediatrics 139(5):708–14

Weitzenblum E, Kessier R, Chaouat A 2002 Alveolar hypoventilation in the obese: the obesity–hypoventilation syndrome. Revue de Pneumologie Clinique 58(2):83–90

Wendelboe A M, Hegmann K T, Biggs J J 2003 Relationships between body mass indices and surgical replacements of knee and hip joints.

American Journal of Preventative Medicine 25(4):290–295 WHO (World Health Organization) 1997 Obesity epidemic puts

millions at risk from related diseases. Online. Available:

http://www.who.int/archives/inf-pr-1997/en/pr97–46.html February 2004

Williamson D F 1999 Pharmacotherapy for obesity. Journal of the American Medical Association 281:278–280

Wiser S, Telch C F 1999 Dialectical behavior therapy for binge-eating disorder. Journal of Clinical Psychology 55(6):755–768

Woolf-May K, Bird S, Owen A 1997 Effects of an 18 week walking programme on cardiac function in previously sedentary or relatively inactive adults. British Journal of Sports Medicine 31(1):48–53

Woolf-May K, Kearney E M, Jones D W et al 1998 The effect of two different 18 week walking programmes on aerobic fitness, selected blood lipids and factor XIIa. Journal of Sports Sciences 16:701–710 Xiong Y, Tanaka H, Richardson J A et al 2001 Endothelin-1 stimulates leptin production in adipocytes. Journal of Biological Chemistry 276(30):28471–28477

Young S S, Kseans S M, Austin T et al 2003 The effects of body fat on pulmonary function and gas exchange in cynomolgus monkeys.

Pulmonary Pharmacology and Therapeutics 16(5):313–319 Zimmermann U, Kraus T, Himmerrich H et al 2003 Epidemiology,

implications and mechanisms underlying drug-induced weight gain in psychiatric patients. Journal of Psychiatric Research 37(3):193–220

Suggested Readings, References and Bibliography 111

INTRODUCTION

The objective of this chapter is to emphasize to the exercise practitioner how acute and habitual physical activity (PA)/exercise may alter the potential of the blood to coagulate or bleed. The aim is also to highlight those individuals who are at increased risk of thrombosis during and after PA/exercise as a result of increased blood coagulation potential (El-Sayed 1996, Gibbs et al 2001, Morris et al 2003).

In document Exercise Prescription - eBook (Page 119-124)