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PREVALENCE OF DEPRESSION AND ASSOCIATED RISK FACTORS AMONG THE ELDERLY

A Dissertation submitted to

THE TAMIL NADU DR. M.G.R. MEDICAL UNIVERSITY, CHENNAI- 600 032

In partial fulfilment of the award of the degree of MASTER OF PHARMACY

IN

Branch-VII –PHARMACY PRACTICE

Submitted by

Name: MUHAMMED SHAHEER .K REG.No.261640205

Under the Guidance of

Dr. N. VENKATESWARAMURTHY, M.Pharm., PhD, DEPARTMENT OF PHARMACY PRACTICE

J.K.K. NATTRAJA COLLEGE OF PHARMACY KUMARAPALAYAM – 638183

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PREVALENCE OF DEPRESSION AND ASSOCIATED RISK

FACTORS AMONG THE ELDERLY

A Dissertation submitted to

THE TAMIL NADU DR. M.G.R. MEDICAL UNIVERSITY,

CHENNAI - 600 032

In partial fulfilment of the award of the degree of

MASTER OF PHARMACY

IN

Branch-VII -- PHARMACY PRACTICE

Submitted by

Name: MUHAMMED SHAHEER .K

REG.No.261640205

Under the Guidance of

Dr. N. VENKATESWARAMURTHY, M.Pharm.,PhD, DEPARTMENT OF PHARMACY PRACTICE

J.K.K. NATTRAJA COLLEGE OF PHARMACY

KUMARAPALAYAM – 638183

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EVALUATION CERTIFICATE

This is to certify that the dissertation work entitled “Prevalence Of Depression And Associated Risk Factors Among The Elderly” submitted by the student bearing [REG.No.261640205] to “The Tamil Nadu Dr. M.G.R. Medical University”, Chennai, in partial fulfillment for the award of Degree of Master of Pharmacy in Pharmacy Practice was evaluated by us during the examination held on………..……….

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CERTIFICATE

This is to certify that the dissertation “Prevalence Of Depression And Associated Risk Factors Among The Elderly” is a bonafide work done by

Reg.No.261640205, Department of Pharmacy Practice, J.K.K. Nattraja College of Pharmacy, Kumarapalayam, in partial fulfillment of the University

rules and regulations for award of Master of Pharmacy in Pharmacy Practice under my guidance and supervision during the academic year 2016-2017.

Dr.R. SAMBATH KUMAR, M.Pharm,Ph.D.,

Principal, J.K.K.Nattraja College of Pharmacy, Kumarapalayam-638 183.

Dr.N.VENKATESWARAMURTHY, M.Pharm,Ph.D.,

Professor and Guide, Department of Pharmacy Practice, J.K.K.Nattraja College of Pharmacy, Kumarapalayam-638 183.

Place: Kumarapalayam

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CERTIFICATE

This is to certify that the work embodied in this dissertation en titled

dissertation “Prevalence Of Depression And Associated Risk Factors Among The Elderly”, submitted to “The Tamil Nadu Dr.M.G.R. Medical University”, Chennai, in partial fulfillment to the requirement for the award of Degree of Master of Pharmacy in Pharmacy Practice, is a bonafide work carried out by Mr.MUHAMMED SHAHEER .K, [REG.No.261640205]during the academic year 2016-2017, under the guidance and direct supervision of

Dr. N.Venkateswaramurthy, M.Pharm., Ph.D., Professor and Head, Department of Pharmacy Practice, J.K.K. Nattraja College of Pharmacy,

Kumarapalayam.

Dr.R. SAMBATH KUMAR, M.Pharm,Ph.D.,

Professor & Principal, J.K.K.Nattraja College of Pharmacy. Kumarapalayam-638 183.

Place: Kumarapalayam

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CERTIFICATE

This is to certify that the work embodied in this dissertation en titled

“Prevalence Of Depression And Associated Risk Factors Among The Elderly”, submitted to “The Tamil Nadu Dr. M.G.R. Medical University”, Chennai, in partial fulfillment to the requirement for the award of Degree of

Master of Pharmacy in Pharmacy practice, is a bonafide work carried out by Mr. MUHAMMED SHAHEER .K, [REG.No.261640205]during the academic year 2016-2017, under the my guidance and direct supervision in

the Department of Pharmacy practice, J.K.K. Nattraja College of Pharmacy,

Kumarapalayam.

Place: Kumarapalayam

Date:

Dr.N.VENKATESWARAMURTHY, M.Pharm,Ph.D.,

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DECLARATION

I do hereby declared that the dissertation “Prevalence Of Depression And Associated Risk Factors Among The Elderly”, submitted to “The Tamil Nadu Dr. M.G.R Medical University”, Chennai, for the partial fulfillment of the degree of Master of Pharmacy in Pharmacy Practice, It is a bonafide research work has been carried out by me during the academic

year 2016-2017, under the guidance and supervision of Dr. N. Venkateswaramurthy, M.Pharm., Ph.D., Professor, Head, Department of Pharmacy practice, J.K.K. Nattraja College of Pharmacy, Kumarapalayam.

I further declare that this work is original and this dissertation has

not been submitted previously for the award of any other degree, diploma,

associate ship and fellowship or any other similar title. The information

furnished in this dissertation is genuine to the best of my knowledge.

Place: Kumarapalayam

Date:

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Dedicated to Parents,

Teachers &

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ACKNOWLEDGEMENT

I express whole hearted gratitude to my guide Dr. N. Venkateswaramurthy, M.Pharm., Ph.D., Professor, Head, Department of Pharmacy practice, J.K.K. Nattraja College of Pharmacy, Kumarapalayam., for suggesting solution to problems faced by me and providing indispensable guidance, tremendous encouragement at each and every step of this dissertation work. Without his critical advice and deep-rooted knowledge, this work would not have been a reality.

It is our most pleasant duty to thank our beloved Principal Dr. R. SambathKumar, M.Pharm., Ph.D., J.K.K. Nattraja College of Pharmacy, Kumarapalayam for ensuring all the facilities were made available to us for the smooth running of this project.

Our sincere thanks to Dr. N. Venkateswaramurthy, M.Pharm., Ph.D., Professor and Head, Department of Pharmacy Practice, Mr. K. Kameswaran. M.Pharm, Lecturer, Department of Pharmacy Practice, Mr.Srinivasan, M.Pharm, Assistant Professor, Department of Pharmacy Practice, Dr. Tanya Jacob. Pharm.D., Lecturer, Department of Pharmacy Practice, Dr. Cindy Jose, Pharm.D., Lecturer, Department of Pharmacy Practice,

Dr.Krishna Ravi, Pharm.D., Lecturer, Department of Pharmacy Practice,

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Our sincere thanks to Dr. Shanmugasundaram, M.Pharm., Ph.D., Vice Principal & HOD, Department of Pharmacology, Mr. V. Venkateswaran, M.Pharm, Assistant Professor, Department of Pharmacology, Mrs. M.Sudha, M.Pharm., Lecturer, Department of Pharmacology, Mrs. R.Elavarasi, M.Pharm., Lecturer, Department of Pharmacology,

Mrs. M.Babykala, M.Pharm., Lecturer, Department of Pharmacology for their valuable suggestions.

Our sincere thanks to Dr. V.Sekar, M.Pharm., Ph.D., Professor & HOD, Department of Pharmaceutical Analysis, Dr. I.Caolin Nimila, M.Pharm., Ph.D., Assistant Professor, Department of Pharmaceutical Analysis, Mrs. V.Devi, M.Pharm., Lecturer, Department of Pharmaceutical Analysis for their valuable suggestions.

Our sincere thanks to Mrs. S. Bhama, M.Pharm., Assistant Professor, Mr. R. Kanagasabai, B.Pharm, Biotech., Assistant Professor, Department of Pharmaceutics, Mr. K. Jaganathan, M.Pharm., Lecturer, Department of Pharmaceutics, Mr. C. Kannan M.Pharm., Lecturer, Department of Pharmaceutics and Mr. Kamalakannan M.Pharm., Lecturer, Department of pharmaceutics for their valuable help during our project.

Our sincere thanks to Dr. M. Vijayabaskaran, M.Pharm., Ph.D., Professor and head Department of Pharmaceutical chemistry, Dr. S. P. Vinoth Kumar, M.Pharm., Ph.D.,

Assistant Professor, Department of Pharmaceutical chemistry, Mrs. S. Gomathi, M.Pharm,

Lecturer, Department of Pharmaceutical chemistry and Mrs. S. Vasuki, M.Pharm., Lecturer, Department of Pharmaceutical chemistry, for their valuable suggestions.

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Department of Pharmaceutical Analysis, Dr. M. Senthilraja, M.Pharm., Ph.D., Assistant Professor, Department of Pharmaceutical Analysis, and Mrs. Carolin, M.Pharm., Lecturer, Department of Pharmaceutical Analysis for their valuable suggestions.

Our sincere thanks to Mrs. P. Meenaprabha, M.Pharm., Lecturer, Department of Pharmacognosy for their valuable suggestions.

We greatly acknowledge the help rendered by Mrs. K. Rani, Office Superintendent,

Mr.E.Vasanthakumar, MCA, Ms.M.Venkateswari, MCA, Typist, Mrs. V. Gandhimathi, M.A., M.L.I.S., Librarian, and Mrs. S. Jayakala, B.A., B.L.I.S., Asst. Librarian for their co-operation.

We are proud to dedicate our deep sense of gratitude to the founder, (Late) Thiru J.K.K. Nattaraja Chettiar, providing us the historical institution to study.

Our sincere thanks and respectful regards to our reverent Chairperson Smt. N. Sendamaraai, B.Com., Director Mr. S. OmmSharravana, B.Com., LLB., J.K.K. Nattraja Educational Institutions, Kumarapalayam for their blessings, encouragement and support at all times.

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CONTENTS

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INFORMATION FOR PATIENT

Dear participant,

I Mr.MUHAMMED SHAHEER .K, [REG.No.261640205] student of

J.K.K.Nattraja College of Pharmacy, Kumarapalayam currently conducting a project entitled “Prevalence Of Depression And Associated Risk Factors Among The Elderly” for the partial fulfillment for the award of Degree of Master of Pharmacy in Pharmacy Practice.

As the part of project we need to collect data regarding my studies from you.

We will appreciate very much if you could kindly assist us to collect your medical data‟s. However identifiable personal data‟s will not be disclosed.

Thank you very much for your kind participation.

CONSENT FORM

I, ____________________________, have read and understand the above information. I have agreed to allow my data to be collected for the project work.

_______________________________ ____________________ Signature of participant Date

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ANNEXURE - (1)

1. Name of the Patient: 2. Address:

3. Gender :

a. male b. female 4. Participant‟s Age

a. 60-70 b. 71-80 c. More than

81

5. Geriatric depression scale (GDS)

DATE:

1 Are you basically satisfied with your life? No Yes

2 Have you dropped many of your activities or interests? Yes No

3 Do you feel that your life is empty? Yes No

4 Do you often feel bored? Yes No

5 Are you in good spirits most of the time? No Yes

6 Are you afraid that something bad is going to happen to you? Yes No

7 Do you feel happy most of the time? No Yes

8 Do you often feel helpless? Yes No

9 Do you prefer to stay at home, rather than going out and doing

new things? Yes No

10 Do you feel you have more problems with your memory than

most? Yes No

11 Do you think it is wonderful to be alive? No Yes

12 Do you feel pretty worthless the way you are now Yes No

13 Do you feel full of energy? No Yes

14 Do you feel that your situation is hopeless? Yes No

15 Do you think that most people are better off than you are? Yes No > 5 problems (answers in BOLD) indicates probable depression

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6. GERIATRIC DEPRESSION SCALE (GDS) - SCORE

1. The GDS short form (15 questions) has been derived from the 30 question version. It has been designed for the assessment of depressive symptomatology in elderly people and excludes any questions relating to the physical symptoms of depression common in old age.

2. The GDS is a screening device and should not be used as a diagnostic tool. It can be used to monitor the client‟s emotional state in relation to treatment or change in physical health. The questionnaire can guide further clinical interviews and when used this way has been found very acceptable to clients.

3. The questions are read out and the patient is asked how they have felt over the past week using a Yes/No response format. No further explanation or interpretation should be given to the questions.

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ANNEXURE - (2)

DEPRESSION PREVALENCE

1. Marital status:

a. Living with spouse b. Either spouse expired c. Other

7. Educational status:

a. Literate b. Illiterate 8. Family type:

a. Joint b. Nuclear 9. Family size:

a. Small ≤ 5 b. Large ≥ 5 10. Family Income:

a. ≤ 10,000 b. > 10,000

11. Past occupational status of the depressive elder‟s (before 60 years): a. Professional / administrative class

b. Others (includes Housewives, clerical & technical staff, teachers & others)

12. Present occupational status of the depressive elder‟s: a. Employed

b. Unemployed

13. Family history of psychiatric illness: a. Present

b. Absent

14. Past history of psychiatric illness: a. Present

b. Absent

15. Lifetime history of substance abuse: a. Present

b. Absent

16. Opportunities for companionship (spends day with someone) a. Yes

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17. Has someone to confide? a. Yes

b. No

18. Makes new friends? a. Yes

b. No

19. Family illness in last 6 months? a. Yes

b. No

20. Death of family member in last 6 months? a. Yes

b. No

21. Number of medical condition? a. 0

b. 1 or 2 c. 3

d. 4 or more

22. Change in weight in past year a. No change

b. Gained 10 kg c. Lost 10 kg

23. Participants reported with Hypertension a. Yes

b. No

24. Number of activities requiring assistance? a. 0

b. 1 c. 2

d. 3 or more

25. Sleep pattern of the patients? a. Yes

b. No

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a. Yes b. No

27. Forgets to take medications or pay bills a. Yes

References

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