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Some considerations in the design and interpretation of antimalarial drug trials in uncomplicated falciparum malaria

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Figure

Figure 1 compares the per protocol estimate A (PP) of thefailure rate and the Kaplan-Meier estimate B (KM) for dif-ferent numbers of patients dropping out from trial follow-up after day 28 and different distributions of observedfailures
Table 2: Illustrating how the "Intention to treat" approach ascribing indeterminate treatment outcomes as failures overestimates the true failure rate

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