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Expression of CCR5 Increases during Monocyte Differentiation and Directly Mediates Macrophage Susceptibility to Infection by Human Immunodeficiency Virus Type 1

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Academic year: 2019

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Figure

FIG. 1. HIV-1 infection of monocytes and MDM. Freshly isolated peripheralblood monocytes and MDM cultured in duplicate for 5 days were infected with
FIG. 3. Surface expression of HIV-1 receptors on monocytes and MDM. Freshly isolated PBMC and MDM cultured for 5 days were stained with MAb specific forCD4, CXCR4 (MAb 12G5), or CCR5 (MAb 2D7 and 5C7) and analyzed by two-color flow cytometry
FIG. 4. CCR5 MAb 2D7 blocks infection of MDM by HIV-1Monocytes and MDM obtained from four donors and analyzed for coreceptorexpression in Fig

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