Nascent human immunodeficiency virus type 1 reverse transcription occurs within an enveloped particle.

The addition of lysates made from mammalian cell lines (Jurkat, HEK293T, and NIH 3T3 cells) to virions delipidated by detergent stimulated late reverse transcription efficiency..

DC-SIGN, a lectin expressed on dendritic cell and macrophage subsets, binds to human immunodeficiency virus Env glycoproteins, allowing capture of viral particles.. Captured

To examine the early events of the life cycle of human immunodeficiency virus type 1 (HIV-1), we analyzed the intracellular complexes mediating reverse transcription isolated

The efficient packaging of genomic RNA into virions of human immunodeficiency virus type 1 (HIV-1) is directed by cis-acting encapsidation signals, which have been mapped to

This correlates the presence of equal amounts of partial reverse transcripts in wild-type and nef-mutated virions (not illustrated) and suggests that Nef stimulates viral DNA

To generate nonpathogenic viral particles which express active human immunodeficiency virus type 1 (HIV-1) protease (PR), plasmids containing sequences from the genomes of HIV-1

We have obtained three-dimensional structures of individual immature and mature HIV-1 virus-like particles by cryoelectron tomography.. Reconstructions of the mature

Mass spectrometric lipid analysis of purified HIV particles HIV-1 virions were purified from cell culture supernatants of infected MT-4 lymphocyte cultures and subjected to