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Circadian clock proteins regulate neuronal redox homeostasis and neurodegeneration

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Figure

Figure 1Marked age-dependent cerebral astroglial activation in mRNA (Bmal1 KO mice. GFAP staining of sections from 6-month-old WT (A) and Bmal1 KO (B) mice shows severe astrogliosis throughout the brain of KO mice and most severe in cortex
Figure 2Synaptic degeneration and impaired functional connectivity in Bmal1 KO cortex
Figure 3Brain-specific deletion of
Figure 3 for comparison), while Aldh2 and Nrf2 showed minimal oscillation (Figure 5F)
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