06 Pathology
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1 1.The aortic valve seen in the
figure was discovered at the autopsy of a 72-year-old male. The heart weighed 580g, with marked left ventricular hypertrophy and minimal coronary arterial atherosclerosis. A serum chemistry panel revealed no abnormalities prior to death from congestive heart failure. Which of the following pathologic processes accounts for the appearance of the valve ?
A. Amyloidosis
B. Dystrophic calcification C. Lipofuscin deposition D. Hemosiderosis
2. A baby born at 36 weeks' gestation shows the facial features and positioning of extremities shown here. The baby soon develops severe respiratory distress. Which of the following conditions best explains these findings?
A. Congenital rubella infection B. Bilateral renal agenesis C. Maternal diabetes mellitus D. Trisomy 13
3. A 27-year-old woman presents with tender cervical lymphadenopathy.
A biopsy of one of the enlarged lymph nodes in this area isdiagnosed by
the pathologist as being a “reactive lymph node with follicular hyperplasia.”The associated schematic depicts the morphology of this reactive change. The majority of the proliferating cells in the area marked by the arrow labeled with an “*” are in the process of transforming into cells that eventually will secrete which substance? a.Erythropoietin b. Gamma-interferon c. Immunoglobulin d. Interleukin-2 4. A 7-year-old girl presents with signs of acute appendicitis including fever and right lower quadrant abdominal pain. A section from the resected appendix is seen in the associated picture. Which one of the listed laboratory tests is most commonly used to diagnose infection with this organism?
a. Examine the stool with an acid-fast stain
b. Measure vitamin B12 levels in the serum c. Perform an anal “Scotch-tape” test
d. Quantitate the amount of fecal fat in a 24-h stool specimen
5. A 41-year-old woman
presents with increasing fatigue, lethargy,
and muscle weakness. Her CBC reveals decreased numbers of erythrocytes, leukocytes, and platelets along with an increase in the MCV of the
erythrocytes. The
associated picture is from a smear of her peripheral blood. Which of the following substances is most likely to be deficient in this individual?
a. Aminolevulinic acid b. Ascorbic acid c. Folic acid d. Retinoic acid
2
6 Pigmented liver is seen in Dubin Johnson
syndrome
Rotors syndrome C Crigler Najjar
syndrome
D Gilberts syndrome
7 Which of the following is not
true of hepatitis B virus
Incubation period 6
weeks
DNA virus C Causes chronic
active hepatitis
D Transmitted
oro-anal route
8 Lipoprotein -- X is elevated i Hypercholesterolemia Primary Biliary
Cirrhosia
C Indian Childhood
Cirrhosis
D Alcoholic Cirrhosis
9 In cirrhosis liver all are seen
except
Loss of normal
architecture
Degeneration of
hepatocytes
C Fatty infiltrations D Loss of
intercellular connective tissue matrix
10 Nutmeg liver is foundin Fatty infitration Amyloidosis C Chronic venous
congestion
D None of the above
11 Non caseating granulomas are
seen in all except
Byssinosis Hodgkin's lymphoma C Metastatic Ca lung D TB
12 All increases chances of deep
vein thrombosis except
OCP Hypertension C Superficial
thrmbophlebitis
D MI
13 Severe hypovolemic shock occurs
when blood volume less is
>10 % > 20% C > 30 % D > 40%
14 Which is least resistant to O2
depletion
Liver Heart C Kidney D Spleen
15 Line of Zahn occurs in Postmortem clot Infarct C Embolus D Coralline
thrombus
16 Migratory thrmbophlebitis is
seen in
Disseminated cancer Rheumatic heart
disease
C Libman Sacks
endocarditis
D All of the above
17 First effect of endotoxin is Endothelial damage Perivascular necrosis C DIC D All of the above
3
19 TLR recognise bacterial products
and stimulate immune response by
Perforin and
granzyme mediated apoptosis
FADD ligand apoptosis C Transcription of
nuclear factor mediated by NFKb which recruits cytokine
D Cyclin
20 Toll like receptor involved in
action of bacterial endotoxin
I II C III D V
21 Not true regarding superantigen
is
Bind T-cell irrespctive of antigen specificity of TCR
bind directly to both
MHC II and TCR causing T-cell activation C Bind to cleft in MHC II Molecule D binds directly to lateral aspect of TCR
22 HLA Class III region genes are
important elements in transplant rejection phenomenon Governing suceptibility to autoimmune diseases C Immune surveillance D Antigen presentation and elimination
23 MHC restriction is a part of all
except
antiviral cytotoxic T -cell
antibacterial helper
T-cell /cytotoxic T-T-cell
C Allograft rejection D Autoimmune
disorder
24 Mixed lymphocyte culture is
used to identify
MHC class I antigens MHC class II antigens C B-lymphocytes D T-helper cells
25 T-cell recognize which antigen in
graft rejection
MHC II MHC I C both D none
26 Characteristic feature of SLE is Uveitis Joint deformity C Polyserositis D Cavity in lung
27 LE cells is a lymphocyte neutrophil C basophil D eosinophil
28 Sicca syndrome is associated
with all except
Midline granuloma Chronic active hepatitis C RA D scleroderma
4
30 Most common primary
immunodeficiency is Common variable immunodeficiecny Isolated IgA immunodeficiency C Wiskott-Aldrich syndrome D AIDS
31 Which is found in DiGeorge
syndrome
Eczema Mucocutaneous
candidiasis
C Absent B and T cells D Total absence of T
cells
32 IgG is normal or slightly reduced
in all except
Wiskott-Aldrich
syndrome
Selective IgA deficiency C DI-George
syndrome
D Common variable
immunodeficiency
33 Shrinking lung is afeature of SLE RA C Scleroderma D Sarcoidosis
34 Amyloidosis is seen in all except Multiple myeloma Hypernephroma C Thymoma D Lymphoma
35 AA amyloid chain is found in Multiple myeloma RA C Gout D Alzheimer's
disease
36 Lardaceous spleen is due to
deposition of amyloid in
Sinusoids of red pulp White pulp C Pencilary artery D Splenic trabeculae
37 Speckled pattern is seen in Anti Sm antibody Anti ds DNA antibody C Anti histone
antibody
D Anti chromatin
antibody
38 Large antigen-antibody reaction
is required to cause
Serum sickness Arthus reaction C Urticaria D Anaphylaxis
39 Mast cell releases all interleukins
except
IL-1 IL-2 C IL-3 D IL-4
40 Anti-fibrillin antibodies are
associated with
RA SLE C Mixed connective
tisssue disease
D Systemic slcerosis
41 All are seen in primary
extraglandular sjogren syndrome except
RA Raynaud's
phenomenon
5
42 Anticentromere antibodies are
most commonly associated with
Diffuse cutaneous
systemic sclerosis
Mixed connective
tissue disease
C CREST syndrome D Polymyositis
43 All are immune complex diseases
except
Serum sickness Farmer's lung C SLE D Graft rejection
44 Anti-nuclear antibodies in SLE
cause
Arthritis LE cell C Endocarditis D CNS lesions
45 NANA antibody is seen in Sarcoidosis TB C Leprosy D Carcinoid
46 AE type of amyloid is seen in Medullary carcinoma
thyroid
Primary amyloidosis C Multiple myeloma D Familial
amyloidosis
47 Lardaceous spleen is seen in Alcoholic hepatitis Chronic active hepatitis C Focal amyloidosis D Diffuse
amyloidosis
48 Serum amyloid associated
protein is found in
Alzheimer's disease Chronic inflammatory
states
C Chronic renal failure D Malignant
hypertension
49 Approximate numberof genes in
human genome is
40000 30000 C 80000 D 100000
50 Lack of differentiation is called Anaplasia Dysplasia C Metaplasia D Hyperplasia
51 Transition from G2 to M phase is
controlled by
Rb protein p53 protein C Cyclin E D Cyclin B
52 Which of the following is not a
cyclin dependent kinase inhibitor ?
p21 p27 C p53 D p57
53 Characteristic pathologic
features in malignant hypertension are
Fibrinoid necrosis Papillary necrosis C Glomerulosclerosis D Focal
glomerulonephritis
54 In Burkitts Lymphoma
chromosomal translocation is between
14 and 18 8 and 14 C 14 and 21 D 18 and 21
6
56 Morphological changes in
Necrosis
Enzymatic digestion Calcium Efflux C Fat accumulation D Fluid accumulation
57 Commonest variety of acute
inflamation is
Purulent
inflammation
Serous inflammation C Catarrhal
inflammation
D Necrotic
inflammation
58 Which of the following best
denotes classical complement pathway activation in immuno inflammatiory conditions C2, C4, and C3 decreaseed C2 and C4 normal C3 is decreased C C3 normal and C2, C4 decreased D C1 and C3 are normal and decreased
59 The 4 classical features of
inflammation ws decribed by
Celsus Hippocrates C Aristotle D Galen
60 Wound contracture is due to Myofibroblast Monocyte C Collagen D Elastin
61 Inflammation is usually Nothing but infection Adverse reaction C Defence mechanism
of the body
D Suppressed
immunological mechaism
62 AFP is increased in Endodermal Sinus
tumour
Teratoma C Dysgerminoma D Choriocarcinoma
63 Metastatic calcification is most
commonly seen in
Cornea Extensor tendon C Lungs D Renal tubles
64 Alcohol keratin is composed of Desmin Prekeratin filaments C Vimentin D Neurofilaments
65 Pre existing antiboids in Renal
transplantation leads to
Hyperacute rejection Acute Rejection C Chronic Rejection D graft Vs Host
Rejection
66 Complement responsible for
activation of baceterial lysis is
C3a C3b C C5-9 D C5
67 Medial calcification is seen in Altheroscloerosis Arteriotosclerosis C Monckebergs
sclerosis
D Dissecting
aneurysm
68 Most common translocation in
follicular lymphomas
14 << 18 17 << 19 C 11 << 14 D 22 << 9
69 AIDS involves T - Helper cells T- cuppressor C T - cytotoxic D B - cells
70 Chemical mediators or
inflammation includes all, except
7
71 Therapeutic oxygen therapy is
not useful in
TOF Interstitial lung disease C Acute pulmonary
edema
D Anaemia hypoxia
72 Commonest cause of
Hypertriglyceridemia is
Abetalipoproteinemia Dysbetalipoprotenemia C LDL receptor
deficiency
D Nephrotic
syndrome
73 Phagocytosis was first stuided
experimentally by
Virchow Robert Koch C Domog D Metchnikoff
74 Amyloidosis is associated with 21 P 22 P C Y chromosome D 17 Q
75 Liquefaction necrosis occurs in Brain Heart C Liver D Kidneys
76 Antibody production is by T cells B cells C K cells D NK cells
77 Following are labile cells except Hepatocytes Epithelium of skin C Intestinal mucosa D Bone marrow
78 Glucose-6- phosphate
dehydrogenase (deficiency) is inherited as
Autosomal dominant autosomal resessive C X-Linked recessive D X-limked dominant
79 Boydens micropore filter
technique is todemonstrate
Chemotaxis Phagocytosis C Defect in leucocytes
function
D None of the above
80 Chediak Higash syndromes is due
to
Defective chemo taxis Defective phagocytosis C Both of the above D None of the above
81 The most important mediator of
chemotaxis among following is
C3b C5a C C567 D C2
82 Integrins include all the following
Receptor Proteins Except
Fibronectin Glycoprotein on platelet surface C Leukocyte adhesion molecule D Platelet derived growth factor
83 Gene preventing nutrition of cell
to propagate and considered as Guardian of genome
p53 gene Rb gene C APF D Nf1
84 Syphilitic aneurysm mostly
involve
Arch of aorta Descending aorta C Abdominal aorta
above the renal arteries
D Abdominal aorta
below the renal arteries
85 All are labile cells except Bone marrow cells Epidermal cells C Living cells of small
intestine
D Hepatocyte
86 Occurrence of leucopenia in
septicemia is due to
Endotoxin Bone marrow
suppression
8
87 The patients with the following
show the maximum deposits of lipofuscin in
Gauchers disease Tay Sachs disease C Acute enteric fever D Severe
mainutrition
88 Wathin-Finkeldy gaint cells are
seen in
Measles Rubella C Influenza D Rickettsial pox
89 Cytokeratin filaments are seen in Lipo sarcoma Neurofibroarcoma C Osteosarcoma D Carcinoma
90 Soft granuloma is typically found
in
Amoeboma Leprosy C tuberculosis D Gumma
91 High molecular weight karatins
are expressed mostly in
Ductal carcinoma breast Adenocarcinoma stomach C Squamous cell carcinoma D Lymphoma
92 The cell most sensitive to
ischaemia is
Myocardial fibers Glial cells of brain C Renal tubular
epithelium
D Cortical neurone
93 Red infarct is encountered in lung Heart C Kidney D Spleen
94 In the stage of Grey hepatization WBC fill the alveoli RBC fill the alveoli C Organisms fill the
alveoli
D Accumulation of
fibrin
95 ESR is decreased in Multiple myeloma Polycythemia C Rheumatic fever D Sickle cell anaemia
96 Keratin is a tumour marker for Carcinoma cervix Neurofibroma C Rhabdomyosarcoma D Chorio carcinoma
97 Calcification in necrotic tissue is
called
Metastatic
calcification
Dystrophic calcification C Calcinosis D Tumoral calcinosis
98 The function of Liposomes is Synthesize steroids Store triglycerides C Cholesterol
breakdown
D Transport
lipoproteins
99 Amtloidosis is seen in all except Diabetes mellitus Colloid carcinoma of
throid
C Acute
pyelonephritis
D Multiple myeloma
100 Phagocytosis of TB bacillus does
not occur because of
Wax D Muramyl dipeptide C Cord factor D Peritrichate Cilia
101 Immediate transient type of
increase vascular permeability in acute inflammation occurs at
Venules Capillaries C Arterioles D All of them
102 In which of the following
conditions bilateral contracted kidneys are characteristically seen?
Amyloidosis Diabetes mellitus. C Rapidly progressive
(crescentic)
glomerulonephritis.
D Benign
9
103 Which of the following is
associated with adult polycystic kidney disease? Berry aneurysms in Circle of Willis Saccular aneurysms of aorta C Fusiform aneurysms of aorta D Leutic aneurysms 104 Following injection of
lymphokines, the same class of immunoglobulin are produced. This is to be referred as:
Group switching Clonal selection C Hybridisation D Class switching
105 The release of tissue
thromboplastin is the
mechanism for DIC in all except:
Massive trauma Extensive surgery C Severe burn D SLE
106 McCallum’s patch is diagnostic of Infective endocarditis Rheumatic
endocarditis
C Myocardial
infarction
D Tetralogy of Fallot
(ToF)
107 Dacrolymus acts through IL2 IL6 C IL3 D IL4
108 All of the following are involved
in the intrinsic pathway except:
Factor XII Factor XI C Factor VII D Factor VIII
109 Which leucotriene is the
adhesion factor for the
neutrophil on the cell surface to attach endothelium
B4 C4 C D4 D E4
110 All of the following vascular
changes are observed in acute inflammation, except:
Vasodilation Stasis of blood C Increased vascular
permeability.
D Decreased
hydrostatic pressure.
111 All of the following are related to
arachidomic acid metabolism except:
Prostacyclin Linoleic acid C Thromboxane D Cationic proteins
112 Irreversible injury in cell is Deposition of Ca++ in
mitochondria
Mitochondrial swelling C Myelin figure D Ribosomes
detachment
113 All of the following statements
are true for cell againg except :
Enlargement of telomere ¯number of mitochondria C Glycolysation of DNA D Glycolysation of RNA
114 All endothelial cells produce
thrombomodulin except those found in:
Hepatic circulation Cutaneous circulation C Cerebral
microcirculation
D Renal circulation
10
116 The philadelphia chromosome is
classically associated with which of the following
CLL CML C Burkits lymphoma D Hairy cell
leukaemia
117 Commonest site of lytic lesion in
multiple myeloma is :
Vertebral column Femur C Clavicle D Pelvis
118 Most common type of
thalassemia is :
Alpha Beta C Gamma D None of the above
119 All are true about anemia of
chronic disease except :
Decreased Iron
binding capacity
Normal serum iron C Increase ferritin D None of the above
120 Macrocytic anaemia is caused by Sideroblastic anemia Thallassemia C Hypothyroidism D Iron deficiency
121 Life span of Lymphocytes is 2-3 dyas Weeks C Months D Many years
122 Blood groups A1 and A2 differ in: Chemical structure of
antigen
Spatial configuration of
antigen
C Molecular groups D Ionic charges on
surface
123 All are histicytosis except: Letter seiwe
syndrome
Chloroma C
Handschuller-christian triad
D Eosinophilic
granuloma
124 All the following are causes of
pleural effusion except :
Thyroid tumors Bronchial carcinoma C Carcinoma breast D Lymphoma
125 Which of the following
histological type lung carcinoma has worst prognosis :
Squamous cell CA Adenocarcinoma C Alveolar-carcinoma D Small cell
carcinoma
126 All the following familial
syndromes are associated with development of pheochromocytomas except: Sturge-Weber syndrome Von Recklinghausen disease
C MEN Type II D Prader-Willi
syndrome.
127 Chemotherapeutic drugs can
cause
Only necrosis Only apoptosis C Both Necrosis and
apoptosis
D Anoikis
128 The tissue of origin of the
Kaposi’s sarcoma is
Lymphoid Vascular C Neural 3 D Muscular
129 Which is not a type III
hypersensitivity reaction
11
130 Langerhan’s cells are : Phagocytic cells Antigen presenting
cells C Seen in Autoimmune conditions D Seen in chronic infection
131 Most common vascular tumour
in AIDS
Kaposi-sarcoma Angio sarcoma C Lymphangioma D Lymphoma
132 Rapid progression of disease
with full blown manifestation in AIDS occurs when T4 cell count falls below:
1000/micro L 500/micro L C 200/micro L D 50/micro L
133 In the mitogen activated protein
kinase pathway, the activation of RAS is counteracted by
Protein kinase C GTPase activating
protein
C Phosphatidyl
inositol
D Inositol
triphosphate
134 Which one of the following is not
used as a tumor marker in testicular tumours?
AFP LDH C HCG D CEA
135 All of the following are familial cancers except
Breast carcinoma Ovarian Ca C Cervical Ca D Colon Ca
136 All are benign mesenchymal
tumours of stomach except:
Leiomyoma Adenoma C Fibroma D Lipoma
137 Warthin-Finkeldey giant cells are
seen in:
Measles Rubella C Influenza D Rickettsial pox
138 Vascular dilation in the
inflammatory response is mediated by all of the following except:
Prostaglandins C3a C Leukotrienes D C5a
139 A single whole body dose of how
many rads could result in death:
100 rads 200 rads C 300 rads D 400 rads
140 Example of Type IV
hypersensitivity is
Serum sickness Granulomatous
reaction
C Schwartzmann
reaction
D Arthus reaction
141 Most common change in
atherosclerotic vessel is Dystrophic calcification Superimposed thrombosis C Aneurysm thrombosis D Haemorrhage
12
143 The native valve with prior
damage is most commonly affected by which of the following organisms :
Pepto-streptococci Staphylococcus aureus C Alpha-hemolytic
streptococci
D Staphylococcus
epidermidis
144 In a patient with acute leukemia,
immunophenotype pattern is CD 19+ve, CD 10+ve, CD33+ve, CD 13+ve. He may probably have
Biphenotypic
leukemia
ALL C AML- M2 D AML-M0
145 Sickle cell trait patient do not have manifestations as that of Sickle cell disease, because :
50% HbS is required
for occurrence of sickling
HbA prevents sickling C 50% sickles D HbA prevents
polymerazitation of HbS
146 Best prognostic type of
Hodgkin’s lymphoma is:
Lymphocytic
predominant
Lymphocytic depletion C Mixed cellularity D Nodular sclerosis
147 All of the following statements
about Hairy cell leukaeumia are true except: Splenomegaly is conspicuous Results from an expansion of neoplastic T lymphocytes
C Cells are positive for Tartarate Resistant Acid Phosphatase
D The cells express
CD25 consistently
148 Ameloblastoma (Adamantinoma)
is found in
Pituitary Mandible C Tibia D All of the above
149 Histopathology of a lung cancer
shows ‘clara cells’ probable diagnosis is:
Squamous cell cancer Bronchio-alveolar
cancer
C Large cell cancer D Papillary
carcinoma
150 All are true about chronic venous
congestion of lung except
Brown & fibrin lung Squamous metaplasia C Hemosiderosis D Fibrosis
151 All of the following are seen in
asbestosis except :
Diffuse alveolar
damage
Calcify pleural plaques C Diffuse pulmonary
interstitial fibrosis
D Mesotheliomas
152 Macrocytic anemias are seen in
all except
Orotic aciduria Thiamine deficiency C Copper deficiency D Liver disease
153 Lacunar cells are seen in which
type of lymphoma
Lymphocyte
predomiant
13
154 The blood coagulation time is
prolonged in the following conditions except Haemophilla Idiopathic thrombocytopenia C Heparin administration D Afibrogenemia
155 Chronic ITP is due to increased platelet
consumption intravascular
Antibody production
against platelets
C Decreased synthesis D Decreased
megakaryocytes
156 Neutrophillia is seen in the
following conditions except
amoebic liver abscess Cellulitis C Enteric fever D Lobar pneumonia
157 Dithionite test is done for
assessing
HbF HbE C Hb A D Hb S
158 DIC is seen with all of following
except
Pancreatic carcinoma Leukemia C Snake bite D AIDS
159 Glanzmans disease is Cogenital defect of
platelets Congenital defect of RBcs C Defect of neutrophils D Clotting factor deficiency
160 False about von willebrand factor
is
Synthesized by
hepatocytes
Deficiency of factor VIII C
C Defect in platelet
adhesion
D None of the above
161 Which is not associated with
sickle cell anemia
ankle ulcer Cardiomegaly C Leucopenia D Fish mouth
vertebra
162 increased osmotic fragility is
seen in
Sickle cell anaemia Thalassemia C Hereditary
spherocytosis
D Hemophilia
163 Microcytic hypochromic anaemia
is seen in
Hereditary
spherocytosis
Thalassemia C Iron deficiency
anaemia
D Pernicious
anaemia
164 Earliest response to iro therapy is Increased in Hb % Reticulocytes C increased PCV D Increased
neutrophils
165 The best suited anticoagulant for
osmotic fragility test is
Heparin EDTA C Trisodium citrate D Potassium oxalate
166 Which is abnormal in classic
haemorrhagic disease of newborn
Platelet count Thrombin time C Fibrinogen level D APTT
167 In haemolytic uraemic syndrome
there is Thrombocytopenia + Renal failure Normal coagulative profile C Microanglopathic haemolytic anaemia
14
168 The ratio of Bone marrow
responsible for Erythropoiesis to granulopoiesis is
3 : 1 1 : 1 C 1 : 3 D 4 : 3
169 Karyotypic change of Acute
Promyelecytic Leukemia is
t 15 : 17 t 18 : 14 C t 8 : 22 D t 11 : 22
170 Platelet count is not decreased in Wiskot Aldrich
syndrome
Henoch Schonlein
purpura
C Dengue fever D immune mediated
lysis
171 For enzymatic estimation blood
is not collected in
EDTA Sodium fluoride C Sodium citrate D Sodium oxalate
172 Eosinophilia is a feature of Aspergillosis Histoplasmosis C Byssiosis D cocidiiomycosis
173 Which does not cause
disseminated intravascular
Snake bite Malaria C Hemophilia D Polycythemia
174 One of the following
endocrinologist wrote about primary aldosteronism and the clinical syndrome is named after him
Cushing Chevostek C Don Nelson D Conn
175 In neuroblastomas, following
metabolites are excreted in urine except
HVA VMA C DOPA D Catecholeamines -
epinephrine
176 Commonest presentation of
Endemic goiter
Asymptomatic Hypkothyroidism C Lump in neck D Hyperthyroidism
177 Commonest primary to give
secondaries to adrenal gland is
Lungs Breast C Bladder D Pancreas
178 Histopathological indicator of
malignancy in
phaseochromocytoma
High nuclear index Pleomorphism C increased mitotic
acitvity
D Vascular invasion
179 Paragangliomas may show
production of
ACTH Catecholamines C GH D ADH
180 Commonest cause of ambiguous
genitalia in a 2 yrars old child is
Klinefelter syndrome 21- hydroxylase
deficiency
C Mixed gonadal
dysgenesis
D Testiular
feminization
181 Amyloid stroma is seen in Papillary ca. thyroid Fillicuaar ca. thyroid C anaplastic ca.
thyroid
D Medullary ca.
15
182 Medullary ca of thyroid is
associated with increase in
Calcitonin Thyroid globulin C T3 D T4
183 Goitrous hypothyroidism
commonly occurs in all of the following except Hashimotos thyroiditis Dyshormonogenesis C Thyroprivic hypothyroidism D Iodine deficiency
184 Commonest cause of raised
serum calcium is
Ectopic secretion Parathyroid
hyperplasia
C Parathyroid
adenoma
D Parathyroid
carcinoma
185 The levels of 17- ketosteroids in
urine is increased in
adrenal tumour only Adrenal and Testicular
tumour
C Liver Secondaries D Bronchongenic
carcinoma
186 Neuroblastoma arises from Adrenal cortex Adrenal medulla C Retro peritoneal
mesenchyma
D Endodermal origin
187 Cushings syndrome is most
commonly seen in
Brochogenic
Carcinoma
Renal Cell carcinoma C Pancreatic
Carcinoma
D Lymphoma
188 Excretion of which of the
following is icreasedin pheochromocytoma
Plasma HMA Serum bradykinin C Urinary VMA D All of the above
189 Which organ is not involves in
MEN Type 1
Pancreas Adrenals C Parathyroid D Pituitary
190 Men syndrome is associated with
incrase in
Papillary ca of thyroid Medullary C Follicular D Anaplastic
191 normal thyroid weight varies
____ with dietary iodine content
Directly proportional Inversely C Inverse cubically D Not fixed
192 The most common
hypersecretory state of anterior pituitary gland
Growth hormone Prolactin C ACTH D ADH
193 Thyroglossal cyst may,
occasionally give rise to ______ carcinoma
Papillary Medullary C Anaplastic D Follicular
194 To diagnose hyperglycemia of
two weeks old the best investigation retrospectively is
Ketone bodies Glycosylated
haemoglobin
C Glucose in the blood D Chromosomal
study
195 Which is true about Addisions
disease
Hypoglycemia Hypolalemia C Hypernatremia D Increased protein
16
196 Condition associated with
obesity is all except
pheochromocytoma Hypothyroidism C insulinoma D Cushings
syndrome
197 The following organs are
involved in MEN type I except
Pituitary Parathyroid C Pheochromocytoma D Pancreas
198 Which substance is essential for
vit D metabolism
Parathormone Calcitonin C Thyroxine D Growth hormone
199 In Hashimotos disease, serum
antibodies are mainly against
Thyroid follicles Thyroxine C Thyroglobulins D Iodine
200 Characteristic feature of pagets
cells is
Eosinophilic
cytoplasm
Large vacuolated
cytoplasm
C Glycogen mass D Multinucleate