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(1)

Predictive Acquisition Cost

q

Introduction to PAC

i

(2)

Agenda

Five key criteria for new price type

Five

 

key

 

criteria

 

for

 

new

 

price

 

type

What

 

is

 

PAC?

Key

 

milestones

 

since

 

launch

(3)

Five Key Criteria for a

New Price Type

New Price Type

Transparency – benchmark bears a genuine 

l i hi h l i i i f h

Led by key NCPDP 

stakeholders/committees:

relationship to the actual acquisition cost of the 

drug. (In addition to this “relevance” definition, 

transparency also sometimes refers to being 

“understandable”.)

stakeholders/committees:

industry found fundamental 

short‐comings in each of the 

existing pricing benchmarks, 

Accessibility– benchmark readily accessible 

and can be readily adopted by the pharmacy 

industry.

consensus was reached on 

what criteria any suitable 

price type must satisfy

Comprehensiveness – benchmark available for 

all branded + generic drug groups.

Timeliness– benchmark updated with a 

frequency appropriate to the quickly changing frequency appropriate to the quickly changing 

actual acquisition costs, especially for generic 

products.

(4)

What is PAC?

Pharmacy Distribution System

• PAC estimates drug Acquisition Costs 

Pharmacy

 

Distribution

 

System

in a transparent and defensible way

• PAC is more closely aligned with true 

drug acquisition cost than any other 

available drug price type available drug price type

• PAC supports both Pricing Analytics 

and Contractual Requirements

– UseUse of of PACPAC(with(with PACPAClowl andand PACPAChi hhighrange)range) 

to determine performance of contracts, 

guide reimbursement rates, improve 

negotiating position

– Use of PACas formal reference in “cost 

plus” contracts orPAC Retailas formal plus  contracts or PAC Retailas formal 

(5)

The PAC Offering

g

The PAC output file delivers PAC (and a range 

PAClowto PAChigh) for each drug on a daily basis. 

PAC tracks acquisition‐cost far better than any of 

the traditional pricing benchmarks (e.g. AWP).

The PAC Dashboard is a convenient browser‐

based tool that allows you to look up the PAC 

value for any particular drug. Other information 

about the drug, including some of the items that 

(6)

Key Milestones Since Launch

y

Launch First PBM First LTC First 2012Q1 2012Q2 2012Q3 2012Q4 2013Q1 First Retail  Chain First Health  Plan First  Wholesaler Go Live! PAC Dashboard Model Update (data design) Model Update (NADAC) Q Q Q Q Q Model Update (codes)

(7)

Expanding Set of Use Cases

p

g

•Operational •Grade out PBMs,  challenge/negotiation  h •State Medicaids: 

•Replace or validate AAC

•Tune SMACs

•Employer / Plan Sponsor: 

PBM l l ti research

•Wholesaler RFP and 

contract pricing 

consistency

• U&C/cash pricing

•Loss File analysis

P f t l AC

PBM proposal evaluation 

/contract  performance 

(consultants)

•Proxy for actual AC; 

acceptable alternative to 

submitting invoices to 

CMS, states, others?

•Defend pricing when 

challenged by payer/PBM + 

challenge aggressive 

payer/PBM MACs

•Proxy for actual acquisition 

•Pharmacy MAC 

optimization: balanced; 

spread

cost; acceptable alternative 

to submitting invoices to 

CMS, states, others? spread

•Identify opportunities to 

create savings for clients

•Improve GER predictability

•Justify pricing (PBM vs 

(8)

PAC Addresses Two Fundamental

Drug Pricing Activities

Drug Pricing Activities

Establishing

 

or

 

assessing

 

specific

 

drug

 

prices

(9)

Use Case – Maximum Allowable Cost (PBM/Payer)

MAC Optimization

PAC range can translate into a range within  which the MAC should lie:

MAC Optimization

Value Proposition

• Balanced and Fair Pricing

which the MAC should lie: *Reduce drug spend‐ Identify 

situations where reimbursement is high

*Pharmacy relations‐Identify 

situations where reimbursement is low

Factor:  pharmacy

per‐script profit target

• Explainable methodology

PAClow PAChigh MAClow MAChigh

Drug Current MAC PAC PAClow PAChigh MAC Low MAC High Proposed Target Price Impact Potential

amlodipine besylate tab 10 mg 0.0915 0.0318 0.0195 0.0441 0.0758 0.1004 Unchanged 0.0915 $      ‐

gabapentin cap 300 mg 0.1235 0.0678 0.0473 0.0883 0.0697 0.1107 Reduce 0.1107 $       13,040.84

glimepiride tab 4 mg 0.3981 0.0616 0.0425 0.0807 0.0814 0.1196 Reduce 0.1196 $       31,319.04

glyburide tab 5 mg 0.2741 0.1565 0.1157 0.1973 0.1391 0.2207 Reduce 0.2207 $       5,788.63

loratadine tab 10 mg 0.0925 0.0667 0.0456 0.0878 0.1234 0.1656 Raise 0.1234 $         (25,653.50)

l t b 1 0 0812 0 0266 0 0155 0 0376 0 0630 0 0851 U h d 0 0812 $

lorazepam tab 1 mg 0.0812 0.0266 0.0155 0.0376 0.0630 0.0851 Unchanged 0.0812 $       ‐

zolpidem tartrate tab 10 mg 0.0706 0.0320 0.0197 0.0444 0.1011 0.1258 Raise 0.1011 $      (6,436.90)

Assumptions:

Min $‐profit/Rx (NOT including dispensing fee): $       2.50 Min %‐profit/Rx (NOT including dispensing fee): 10%

(10)

Use Case – Loss-File Analysis (Retail Pharmacy)

Purchasing and Reimbursement

Purchasing and Reimbursement

For

 

any

 

specific

 

claims,

 

a

 

pharmacy

 

can

 

use PAC and ranges (PAC

low

and PAC

high

) to

Value

 

Proposition

• Quickly identify if loss file issues

use

 

PAC

 

and

 

ranges

 

(PAC

low

and

 

PAC

high

)

 

to

 

identify

 

which

 

party

 

it

 

should

 

direct

 

its

 

attention

 

towards:

i.

Identify

 

claims

 

where

 

the

 

• Quickly identify if loss‐file issues 

are due to:

(a) Payer/PBM reimbursement 

OR

Payer/PBM

 

is

 

paying

 

less

 

than

 

PAC

low

ii.

Identify

 

claims

 

where

 

the

 

Wholesaler/Manufacturer

 

is

 

h

i

th

PAC

(b) Procurement

charging

 

more

 

than

 

PAC

high

• 58% of claims had a reimbursement price lower than AC 

• Claims which satisfied one of the criteria above

AClow AChigh

(i) Reimburse < PAC‐low (ii)Acquisition > PAC‐high

(11)

Use Case – Generic Effective Rate (GER)

GER Relevance and Stability

GER Relevance and Stability

GER to measure Price list quality

• GER approach is an effective  AWP

measurement of a price list’s 

performance if using  an underlying 

reference that tracks acquisition cost

PBM

 

case

 

study

 

for

 

a

 

Medicaid

 

book

 

of

 

business

 

target

 

74%

 

GER

 

for MAC performance measurement

for

 

MAC

 

performance

 

measurement

AWP

• Because AWP is so disconnected from 

i iti t d h f th $1 2

$1.4 $1.6 $1.8 $2.0

AC vs AWP (zoomed in)

acquisition cost, and hence from the 

PBM’s MAC, the GER varies 

dramatically across GCNs when based 

on AWP $0.2 $0.4 $0.6 $0.8 $1.0 $1.2 AW P

(12)

Use Case – Generic Effective Rate (GER)

GER Relevance and Stability (cont’d)

GER Relevance and Stability (cont d)

AWP

GER to measure Price list quality

• GER approach is an effective 

measurement of a price list’s 

performance if using  an underlying 

reference that tracks acquisition cost

PBM

 

case

 

study

 

for

 

a

 

Medicaid

 

book

 

of

 

business

 

target

 

74%

 

GER

 

for MAC performance measurement

for

 

MAC

 

performance

 

measurement

AWP

based

 

GER

 

measure

 

sensitive

 

to

 

utilization

 

mix

 

movement

• E.g. ~68% for Acute meds, while ~%85 

(13)

Use Case – Generic Effective Rate (GER)

GER Relevance and Stability (cont’d)

GER Relevance and Stability (cont d)

AWP

GER to measure Price list quality

• GER approach is an effective 

measurement of a price list’s 

performance if using  an underlying 

reference that tracks acquisition cost

PBM

 

case

 

study

 

for

 

a

 

Medicaid

 

book

 

of

 

business

 

target

 

74%

 

GER

 

for MAC performance measurement

for

 

MAC

 

performance

 

measurement

Basing

 

GER

 

on

 

an

 

PAC

 

Retail

 

(i.e.

 

AC

 

“MSRP”)

 

reference

PAC Retail

• Looking across GCNs, a PAC Retail 

based GER is tightly centered around 

(14)

Use Case – Generic Effective Rate (GER)

GER Predictability

GER Predictability

Beyond AWP’s disconnect with true acquisition cost, another issue exists when 

measuringg MAC performancep  based on GER:  

When looking across NDC’s within a GCN, the AWP often varies even though  PBM’s MAC is fixed at the GCN level

Outcome:  Resulting GER depends in part on which manufacturers a pharmacy 

Drug Label PBM MAC NDC AWP GER

TRETINOIN 0 05% CREAM 1 1860 45802036142 2 09511 43%

g p p f p y

purchases from (i.e. which NDCs within a GCN are utilized), adding a degree of 

uncertainty for PBM when targeting GER‐based performance metrics

TRETINOIN 0.05% CREAM 1.1860 45802036142 2.09511 43%

TRETINOIN 0.05% CREAM 1.1860 43478024220 2.51100 53%

HYDROCODON‐ACETAMINOPHEN 5‐500 0.0440 00406035705 0.19686 80%

HYDROCODON‐ACETAMINOPHEN 5‐500 0.0440 00591034901 0.50650 92%

PAC Retail exhibits little to no variance across NDCs within a GCN

Therefore, while the PAC Retail‐based GER is fixed at 74%, the same GCN utilization 

could result in an AWP‐based GER of anywhere from 68% to 77% (depending on 

(15)

Use Case – Retail Pharmacy

Grading out Payers/PBMs

Grading out Payers/PBMs

Plan GER (PAC)

Plan 1 55.6%

Plan 2 57.4%

Value

 

Proposition

• Rank Payers/PBMs based on 

Plan 3 60.6% Plan 4 59.2% Plan 5 59.8% Plan 6 57.6% Plan 7 58.7% Plan 8 59 3% y / reimbursement

• Quickly identify opportunities to 

seek improvement

Compare

 

each

 

PBM’s

 

reimbursement

 

to

 

some

 

common,

 

independent

 

measure

Plan 8 59.3% Plan 9 66.6% Plan 10 63.0% Plan 11 67.4% Plan 12 51.0% Plan 13 24.9%

– Difficult to use AWP because resulting GER is so 

sensitive to drug mix, and even to manufacturer 

from whom drug is purchased.

For each plan an overall GER based on PAC

Plan 14 43.1% Plan 15 60.1% Plan 16 58.7% Plan 17 58.4% Plan 18 53.9% Plan 19 66.2%

For

 

each

 

plan,

 

an

 

overall

 

GER

 

based

 

on

 

PAC

 

Retail

 

was

 

calculated

Plan 9 66. % Plan 20 41.2% Plan 21 66.3% Plan 22 69.2% Plan 23 72.8% Plan 24 44.6%

(16)

PAC

 

is

 

published

 

exclusively

 

by

 

Elsevier/Gold

 

Standard.

 

If

 

you

 

have

 

questions

 

about

 

PAC,

 

please

 

also

 

feel

 

free

 

to

 

contact

 

Glass

 

Box

 

Analytics

 

directly:

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