Nervous Tissue
Nervous Tissue
Pages 236-252
Pages 236-252
I. Functions
I. Functions
A.
A.
Sensory input – senses stimuli occurring
Sensory input – senses stimuli occurring
inside and outside of the body
inside and outside of the body
A.
A.
Integration – analyzes sensory information in
Integration – analyzes sensory information in
order to make a decision
order to make a decision
A.
A.
Motor output – response to stimuli by
Motor output – response to stimuli by
activating muscles, glands, or other parts of
activating muscles, glands, or other parts of
II. Structural Organization
II. Structural Organization
A.
A. Central Nervous Central Nervous
System (CNS) is System (CNS) is composed of
composed of 1. Brain
1. Brain
2. Spinal Cord 2. Spinal Cord
B. Peripheral Nervous B. Peripheral Nervous
System (PNS) is System (PNS) is composed of
composed of
III. Histology
III. Histology
A.
A.
Neurons – conduct nervous impulses from one
Neurons – conduct nervous impulses from one
part of the body to another; basic information
part of the body to another; basic information
processing unit
processing unit
1.
1.
Structure
Structure
a. Dendrites – initially receive
a. Dendrites – initially receive
impulses
impulses
and carry them to the cell
and carry them to the cell
body
body
b. Cell body – contains the nucleus
b. Cell body – contains the nucleus
and
i.
i. Axon terminalAxon terminal – end of axon – end of axon ii.
ii. Synaptic end bulbsSynaptic end bulbs – ends of axon terminals; – ends of axon terminals; form junctions with muscle, nervous, or glandular form junctions with muscle, nervous, or glandular
tissue tissue
iii.
iii. MyelinMyelin – lipid-protein covering that – lipid-protein covering that protects, protects, insulates, and speeds transmission
insulates, and speeds transmission iv.
iv. Schwann cellsSchwann cells – (neurolemmacytes – not – (neurolemmacytes – not part part of the CNS), produce myelin
of the CNS), produce myelin v.
v. Nodes of RanvierNodes of Ranvier – spaces on the axon – spaces on the axon between Schwann cells
between Schwann cells vi.
vi. NeurolemmaNeurolemma – sheath covering Schwann – sheath covering Schwann cellscells C. Axons – extension that sends impulse to another C. Axons – extension that sends impulse to another
2. Types of Neurons
2. Types of Neurons
a.
a. SensorySensory (afferent) – (afferent) –
conduct impulses to the conduct impulses to the brain and spinal cord
brain and spinal cord
b.
b. MotorMotor (efferent) – (efferent) –
conduct impulses away conduct impulses away from the brain and
from the brain and
spinal cord to muscles spinal cord to muscles and glands
and glands
c.
c. InterneuronsInterneurons – conduct – conduct
impulses from sensory impulses from sensory neurons to motor
neurons to motor neurons
B. Neuroglia – function in support,
B. Neuroglia – function in support,
insulation, and protection
insulation, and protection
1.
1.
Type in the CNS
Type in the CNS
a.
a.
Astrocyte
Astrocyte
– star shaped cells that hold
– star shaped cells that hold
bloood vessel to neurons
bloood vessel to neurons
b.
b.
Microglia
Microglia
– phagocytic cells that
– phagocytic cells that
monitor the CNS
monitor the CNS
c.
c.
Oligodendrocyte
Oligodendrocyte
– form myelin sheaths
– form myelin sheaths
in CNS
in CNS
d.
2. Types in the PNS
2. Types in the PNS
a.
a.
Schwann cells – produces myelin
Schwann cells – produces myelin
sheaths for PNS
sheaths for PNS
b.
b.
Satellite cells – support neurons in
Satellite cells – support neurons in
C. Axon bundles
C. Axon bundles
1.
1.
In the PNS the bundles form WHITE
In the PNS the bundles form WHITE
MATTER, they are white because of
MATTER, they are white because of
the myelin, the white matter
the myelin, the white matter
propagates nerve signals.
propagates nerve signals.
2.
2.
In the CNS the cell bodies and
In the CNS the cell bodies and
unmyelinated axons are called
unmyelinated axons are called
GRAY MATTER. This tissue
GRAY MATTER. This tissue
IV. Nerve Impulses – tiny electric currents that
IV. Nerve Impulses – tiny electric currents that
travel along the surface of a neuron
travel along the surface of a neuron
membrane
membrane
A.
A.
Na-K pump
Na-K pump
– ion gated; functions in
– ion gated; functions in
transmitting the impulses
transmitting the impulses
1. This process propagates the nerve
1. This process propagates the nerve
signal down the axon.
signal down the axon.
2. The charges on the Na and the K
2. The charges on the Na and the K
changes the charge on each side of the
changes the charge on each side of the
B. Functions
B. Functions
1.
1.
Excitability – the ability to respond
Excitability – the ability to respond
to a stimulus and convert it into a
to a stimulus and convert it into a
nerve impulse (electrochemical)
nerve impulse (electrochemical)
a. Threshold stimulus – any
a. Threshold stimulus – any
stimulus that is strong enough to
stimulus that is strong enough to
initiate a nerve impulse
initiate a nerve impulse
b. All or none response – once the
b. All or none response – once the
threshold is reached, the impulse is
threshold is reached, the impulse is
conducted down the entire axon at
conducted down the entire axon at
c. Stimulus changes the permeability
c. Stimulus changes the permeability
to the neuron membrane allowing
to the neuron membrane allowing
Na+ to enter the cell (
Na+ to enter the cell (
depolarization
depolarization
)
)
d. Electrical condition of the resting
d. Electrical condition of the resting
stage (
stage (
polarized
polarized
) is restored by the
) is restored by the
diffusion of K+ out of the cell, this is
diffusion of K+ out of the cell, this is
called
2. Conductivity – the ability to
2. Conductivity – the ability to
transmit the impulse to the other
transmit the impulse to the other
neurons, muscles, or glands
neurons, muscles, or glands
a.
a.
Neurotransmitters are released from
Neurotransmitters are released from
the axon terminal of a presynaptic
the axon terminal of a presynaptic
neuron into the synaptic cleft
neuron into the synaptic cleft
b.b.
Neurotransmitter binds to a specific
Neurotransmitter binds to a specific
molecule in the membrane of a
molecule in the membrane of a
postsynaptic neuron. This stimulates
postsynaptic neuron. This stimulates
the impulse conduction by the
the impulse conduction by the
Spinal Cord and Brain
Spinal Cord and Brain
I.
I. Meninges are Meninges are
connective tissues that connective tissues that cover the organs of the cover the organs of the CNS
CNS
a. Dura Mater (
a. Dura Mater (tough tough
mother)
mother) – outermost – outermost
layer; provides protection layer; provides protection for the organ
for the organ b.
b. Arachnoid mater – Arachnoid mater –
middle layer; resembles middle layer; resembles a spider web
a spider web c.
c. Pia Mater – inner layer; Pia Mater – inner layer;
adheres to the surface of adheres to the surface of the organ
II. Spinal Cord
II. Spinal Cord
A.
A. Location – extends Location – extends
from magnum foreman from magnum foreman of the occipital bone to of the occipital bone to the second lumbar
the second lumbar vertebrae.
vertebrae.
B.
B. Cauda equina Cauda equina (horse’s (horse’s
tail) – nerves arising tail) – nerves arising from the spinal cord. from the spinal cord.
C.
C. H-shaped interior H-shaped interior
portion is gray matter. portion is gray matter.
D.
D. Outer portion is called Outer portion is called
white matter; tracts white matter; tracts called
called
E. Functions
E. Functions
A.
A.
Primary reflex center
Primary reflex center
1. Reflex arcs – conduction of nerve
1. Reflex arcs – conduction of nerve
impulses results in a reflex.
impulses results in a reflex.
2. Somatic arcs control skeletal muscle
2. Somatic arcs control skeletal muscle
3. Autonomic arcs control smooth and
3. Autonomic arcs control smooth and
cardiac muscle and glands
cardiac muscle and glands
B. Sensory impulses ascend through tracts
B. Sensory impulses ascend through tracts
III. Brain is composed of about 100
III. Brain is composed of about 100
billion neurons and weighs about 3
billion neurons and weighs about 3
lbs.
lbs.
A.
A. CerebrumCerebrum
1.
1. Largest part of brainLargest part of brain 2.
2. Ridges are called gyrus made by Ridges are called gyrus made by the folds
the folds 3.
3. Spaces between the gyrus are Spaces between the gyrus are called sulci
called sulci 4.
4. Deepest sulci are fissuresDeepest sulci are fissures a.
a. Longitudinal fissure Longitudinal fissure divides divides the cerebrum into the left and the cerebrum into the left and right hemispheres joined
right hemispheres joined together by the
together by the corpus corpus collosum
collosum and allows the right and allows the right and left to communicate
b.
b.
Central Fissure
Central Fissure
(fissure of
(fissure of
Rolando)
Rolando)
separates frontal and
separates frontal and
parietal lobes
parietal lobes
c.
c.
Lateral fissure
Lateral fissure
separates frontal
separates frontal
5. Lobes are identified by the bones
5. Lobes are identified by the bones
that cover them
that cover them
a.
a. FrontalFrontal
i. Motor skills (located in i. Motor skills (located in precentral gyrus)
precentral gyrus)
ii. Broca’s area – generally ii. Broca’s area – generally on the left side, controls on the left side, controls motor speech
motor speech
iii. Intelligence and iii. Intelligence and abstract reasoning abstract reasoning
b. Parietal b. Parietal
i. Somatic sensory area i. Somatic sensory area ii. Reading
c. Temporal
c. Temporal
i. Auditory
i. Auditory
ii. Language/speech comprehension
ii. Language/speech comprehension
d. Occipital
d. Occipital
i. Visual
i. Visual
6.
6.
Cerebral cortex
Cerebral cortex
– the thin layer of
– the thin layer of
gray matter (non-myelinated) on the
gray matter (non-myelinated) on the
7. Interior of the brain
7. Interior of the brain
is composed of white
is composed of white
matter (myelinated)
matter (myelinated)
a. Within the white
a. Within the white
matter there are
matter there are
paired masses of
paired masses of
gray matter called
gray matter called
basal nuclei
basal nuclei
that
that
control skeletal
control skeletal
muscle movements.
8. Diencephalon –
8. Diencephalon –
interbrain; lies on top of
interbrain; lies on top of
the brain stem and is
the brain stem and is
enclosed by the cerebral
enclosed by the cerebral
hemispheres
hemispheres
a. Thalamus – dumbbell
a. Thalamus – dumbbell
shaped mass of gray
shaped mass of gray
matter in each cerebral
matter in each cerebral
hemisphere
hemisphere
i. relays sensory
i. relays sensory
impulses to cerebral
impulses to cerebral
cortex sensory areas
cortex sensory areas
ii. Produces emotions of
ii. Produces emotions of
pleasantness and
pleasantness and
unpleasantness with
b. Hypothalamus – consists mainly
b. Hypothalamus – consists mainly
of the posterior pituitary gland,
of the posterior pituitary gland,
pituitary stalk, and gray matter
pituitary stalk, and gray matter
i.
i. Major center for Major center for
controlling the ANS controlling the ANS (controls internal (controls internal organs)
organs)
ii.
ii. Controls hormone Controls hormone
secretions by anterior secretions by anterior and posterior pituitary and posterior pituitary gland
gland
iii.
iii. Contains center for Contains center for
controlling normal body controlling normal body temp, feeling of pain, temp, feeling of pain, rage, aggression,
rage, aggression, pleasure, appetite, pleasure, appetite, thirst, and sleep thirst, and sleep patterns
c. Pituitary gland –
c. Pituitary gland –
master gland in
master gland in
body
body
d. Pineal gland –
d. Pineal gland –
melatonin secretion
melatonin secretion
controls the body’s
controls the body’s
IV. Cerebellum
IV. Cerebellum
a.
a. Second largest part of Second largest part of
brain brain
b.
b. Composed of an outer Composed of an outer
layer of gray matter and layer of gray matter and an inner layer of white an inner layer of white matter
matter
c.
c. Lies behind the medulla Lies behind the medulla
and pons and under the and pons and under the occipital lobe
occipital lobe
d.
d. Functions include muscle Functions include muscle
coordination, equilibrium, coordination, equilibrium, memory, and regulation of memory, and regulation of balance and posture
V. Brain Stem
V. Brain Stem
A.
A.
Medulla Oblongata
Medulla Oblongata
1. Located in the inferior and
1. Located in the inferior and
posterior portion of the cranial
posterior portion of the cranial
cavity; just superior to the foramen
cavity; just superior to the foramen
mangnum
mangnum
2. Contains all sensory (ascending)
2. Contains all sensory (ascending)
tracts and motor (descending) tracts
tracts and motor (descending) tracts
that run between the brain and
that run between the brain and
spinal cord
3. The white and gray matter are closely 3. The white and gray matter are closely
intertwined intertwined
4. The
4. The pyramidspyramids – 2 triangular structures that – 2 triangular structures that make up the medulla; contain the motor tract make up the medulla; contain the motor tract
5. The pyramid on the right side
5. The pyramid on the right side
controls the left side of the body and
controls the left side of the body and
visa versa
visa versa
6. Controls vital center functions
6. Controls vital center functions
II. Pons
II. Pons
1.
1.
Located superior
Located superior
to the medulla
to the medulla
2.2.
Gray and white
Gray and white
matter
matter
arrangement
arrangement
similar to that of
similar to that of
medulla
medulla
3.3.
Some of the
Some of the
cranial nerves
cranial nerves
III. Midbrain
III. Midbrain
1.
1.
Extends from lower
Extends from lower
portion of pons to
portion of pons to
the diencephelon
the diencephelon
2.
2.
Connect cerebral
Connect cerebral
cortex with the
cortex with the
pons and the spinal
pons and the spinal
cord
cord
3.
3.
Some of the cranial
Some of the cranial
nerves originate
nerves originate
IV. Throughout the brain stem, the
IV. Throughout the brain stem, the
midbrain, and the diencephalon is
midbrain, and the diencephalon is
the
the
reticular formation
reticular formation
The reticular
The reticular
formation is a
formation is a
netlike group of
netlike group of
neurons. It
neurons. It
receives and
receives and
integrates input
integrates input
from the cerebral
from the cerebral
cortex, cerebellum,
cortex, cerebellum,
and spinal cord
V. Cerebrospinal Fluid
V. Cerebrospinal Fluid
1.
1.
Fills spaces in the
Fills spaces in the
brain called
brain called
ventricles.
ventricles.
2.2.
2 Functions:
2 Functions:
Protection &
Protection &
circulation
circulation
3.3.
Formed by the
Formed by the
choroid
choroid
plexuses
PNS
PNS
I.
I.
Cranial Nerves
Cranial Nerves
A. 12 pair that attach to the
A. 12 pair that attach to the
undersurface of brain
undersurface of brain
B. Connect brain with the neck and
B. Connect brain with the neck and
structures in the throat and
structures in the throat and
C. Nerves
C. Nerves
1.
1.
Olfactory (1) {sensory} – sense of smell
Olfactory (1) {sensory} – sense of smell
2.
2.
Optic (2) {sensory} – vision
Optic (2) {sensory} – vision
3.
3.
Oculomotor (3) {motor} – eyeball &
Oculomotor (3) {motor} – eyeball &
eyelid movements and pupil constriction
eyelid movements and pupil constriction
4.4.
Trochlear (4) {motor} – eye movements
Trochlear (4) {motor} – eye movements
(superior oblique)
(superior oblique)
5.5.
Trigeminal (5) {both} – sensation of the
Trigeminal (5) {both} – sensation of the
face, oral cavity, and chewing
face, oral cavity, and chewing
6.6.
Abducens (6) {motor} – turning eyes out
Abducens (6) {motor} – turning eyes out
(lateral rectus)
Cranial Nerves, Cont.
Cranial Nerves, Cont.
7. Facial (7) {both} – sense of taste,
7. Facial (7) {both} – sense of taste,
contraction of the facial, throat, and ear
contraction of the facial, throat, and ear
muscles
muscles
8. Vestibulocochlear (8) {sensory} – hearing
8. Vestibulocochlear (8) {sensory} – hearing
and balance
and balance
9. Glassopharyngeal (9) {both} – sensation
9. Glassopharyngeal (9) {both} – sensation
of throat and taste; swallowing
of throat and taste; swallowing
10. Vagus (10) {both} – extends to
10. Vagus (10) {both} – extends to
abdomen; sensation of throat, larynx, and
abdomen; sensation of throat, larynx, and
thoracic and abdominal organs (and
thoracic and abdominal organs (and
regulation), moves tongue, voice production
Cranial Nerves, Cont.
Cranial Nerves, Cont.
11. Accessory (11) {motor} –
11. Accessory (11) {motor} –
shoulder movements, turning head
shoulder movements, turning head
12. Hypoglossal (12) {motor} –
12. Hypoglossal (12) {motor} –
tongue movements
tongue movements
O
O
h
h
O
O
nce
nce
O
O
ne
ne
T
T
akes
akes
T
T
he
he
A
A
natomy
natomy
F
F
inal
inal
V
V
ery
ery
G
G
ood
ood
V
V
acations
acations
A
A
re
re
H
II. Spinal Nerves
II. Spinal Nerves
A.
A.
Nerves arise from ventral roots and
Nerves arise from ventral roots and
dorsal roots off of the spinal cord
dorsal roots off of the spinal cord
B.
B.
Dorsal contains sensory neurons
Dorsal contains sensory neurons
Spinal Nerves
Spinal Nerves
C.
C. 31 pairs are named and 31 pairs are named and
numbered according to numbered according to what region of the spinal what region of the spinal cord they originate from cord they originate from 1. Cervical Nerves – 8 1. Cervical Nerves – 8 pairs
pairs
2. Thoracic Nerves – 12 2. Thoracic Nerves – 12 pairs
pairs
3. Lumbar Nerves – 5 3. Lumbar Nerves – 5 pairs
pairs
4. Sacralspinal nerves – 5 4. Sacralspinal nerves – 5 pairs
pairs
5. Coccygeal nerves – 1 5. Coccygeal nerves – 1 pair
D. When a spinal nerve leaves the
D. When a spinal nerve leaves the
vertebral column, it divides into
vertebral column, it divides into
branches called
branches called
rami
rami
.
.
1. Dorsal – deep muscles and skin of
1. Dorsal – deep muscles and skin of
back
back
2. Ventral – superficial muscles of
2. Ventral – superficial muscles of
back, structures of limbs, and trunk
back, structures of limbs, and trunk
E. A network of adjacent nerves is called
E. A network of adjacent nerves is called
plexuses.
plexuses.
All spinal nerves form
All spinal nerves form
plexuses except the thoracic nerves;
plexuses except the thoracic nerves;
they go directly to the muscles and
they go directly to the muscles and
skin of trunk.
Plexuses
Plexuses
1.
1.
Cervical – skin and muscles of the
Cervical – skin and muscles of the
head, neck, shoulders, and
head, neck, shoulders, and
diaphragm (phrenic nerve)
diaphragm (phrenic nerve)
2.2.
Brachial – upper arms, neck, and
Brachial – upper arms, neck, and
shoulders (carpal tunnel)
shoulders (carpal tunnel)
a.
a.
Axillary (rotates and abducts arm)
Axillary (rotates and abducts arm)
b.
b.
Radial (flexes forearm and extends
Radial (flexes forearm and extends
fingers)
fingers)
c.
Plexuses
Plexuses
3. Lumbar – abdominal wall, external
3. Lumbar – abdominal wall, external
genitalia, and lower limbs
genitalia, and lower limbs
a. Obturator (rotates and adducts thigh)
a. Obturator (rotates and adducts thigh)
b. Femoral ( flexes thigh and extends
b. Femoral ( flexes thigh and extends
leg)
leg)
4. Sacral – buttocks and lower limbs
4. Sacral – buttocks and lower limbs
a. Tibial (flexes foot, leg, and toes)
a. Tibial (flexes foot, leg, and toes)
Functional Nervous System
Functional Nervous System
I.
I. Somatic Nervous SystemSomatic Nervous System
a.
a. Function – transmit action potentials from CNS to Function – transmit action potentials from CNS to
skeletal muscle. skeletal muscle.
II. Autonomic Nervous System
II. Autonomic Nervous System
A.
A.
Function – transmits action potential
Function – transmits action potential
from CNS to smooth muscle.
from CNS to smooth muscle.
1. Automatic response
1. Automatic response
2. Receives impulses from ANS and have
2. Receives impulses from ANS and have
B. In the ANS there are two motor
B. In the ANS there are two motor
neurons and a ganglia
neurons and a ganglia
1.1.
The first neuron (
The first neuron (
preganglionic
preganglionic
neuron
neuron
) which are myelinated, comes
) which are myelinated, comes
from the CNS and relays to the ganglia.
from the CNS and relays to the ganglia.
2.2.
The second neuron (
The second neuron (
postganglionic
postganglionic
neuron
neuron
), which are unmyelinated,
), which are unmyelinated,
comes from the ganglia and delivers an
comes from the ganglia and delivers an
action potential to the visceral effector
action potential to the visceral effector
(organ).
(organ).
3.3.
Ganglia receive messages and direct to
Ganglia receive messages and direct to
appropriate postganglionic neuron.
III. Divisions of Autonomic
III. Divisions of Autonomic
A.
A.
Sympathetic
Sympathetic
1.
1. Concerned with processes involving Concerned with processes involving expending energy.
expending energy. 2.
2. Contains the parasympathetic system to Contains the parasympathetic system to maintain homeostasis.
maintain homeostasis. 3.
3. Active during times of extreme stress, Active during times of extreme stress, emotion, and exercise.
emotion, and exercise. 4.
4. Fight or Flight response.Fight or Flight response.
a.
a. Pupils dialatePupils dialate
b.
b. Heart rate increase Heart rate increase
c.
B. Parasympathetic
B. Parasympathetic
1.
1.
Concerned with conservation of energy
Concerned with conservation of energy
2.
Summary
Summary
1.
1.
Stimulus (pin in paw) – Activation of
Stimulus (pin in paw) – Activation of
receptor
receptor
2.
2.
Activation of Sensory Neuron
Activation of Sensory Neuron
3.
3.
Info processing in CNS
Info processing in CNS
4.
4.
Activation of Motor Neuron