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Epimutational profile of hematologic malignancies as attractive target for new epigenetic therapies

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Figure

Figure 1: Representative proteins involved in DNA methylation and histone modifications that were identified to be recurrently mutated, translocated or aberrantly recruited in hematological malignancies
Table 1: Summary of clinical trials examining DNA hypomethylating agents (DHA) alone or in combination with Histone Deacetylase inhibitors in hematological malignanciesDHAPhaseCombinationHematological diseaseIdentifierstate
Table 2: Summary of clinical trials examining Histone Deacetylase, Histone Methyltransferase, and Bromodomain inhibitors in hematological malignancies

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