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Prophylactic onabotulinumtoxinA in patients with chronic migraine and comorbid depression: An open-label, multicenter, pilot study of efficacy, safety and effect on headache-related disability, depression, and anxiety

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Academic year: 2020

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Figure

Table I Patient characteristics at screening
Table 3 changes in health-related quality of life assessed using sF-36® Version 2.0
Figure 2 changes in impact and disability associated with depression and anxiety: patient responses (A) and change from baseline in total score (B).Notes: The PHQ-9 question 10/GAD-7 question 8 was “If you checked off any problems, how difficult have these problems made it for you to do your work, take care of things at home, or get along with other people?” **P=0.0054 vs baseline.Abbreviations: GaD-7, seven-item Generalized anxiety Disorder questionnaire; PhQ-9, nine-item Patient health Questionnaire depression module; sD, standard deviation.

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