I.
I.
Pulmonary Ventilation
Pulmonary Ventilation
Gas exchange between atmosphere and Gas exchange between atmosphere and
lungs. Gas flow in is regulated by pressure
lungs. Gas flow in is regulated by pressure
differences.
Respiration Respiration is the process of bringing in is the process of bringing in oxygen to supply the blood cells with, and oxygen to supply the blood cells with, and
removing carbon dioxide produced by removing carbon dioxide produced by
cellular activity (cellular respiration). cellular activity (cellular respiration).
Respiration is made up of three Respiration is made up of three
processes: 1) Pulmonary Ventilation processes: 1) Pulmonary Ventilation
2) External Respiration2) External Respiration
A. Process of Inspiration
A. Process of Inspiration
(breathing in)
(breathing in)
1.
1. Volume of thoracic cavity changesVolume of thoracic cavity changes
a. The volume increases and the pressure
a. The volume increases and the pressure
decreases.
decreases.
b. The inspiration muscles (diaphragm and the
b. The inspiration muscles (diaphragm and the
intercostals) contract.
intercostals) contract.
i. Diaphragm flattens (it is usually
i. Diaphragm flattens (it is usually
curved up).curved up).
ii. Intercostals pull the ribs up and
ii. Intercostals pull the ribs up and
the
2. Pressure
2. Pressure
The pressure in the The pressure in the
lungs (alveolar
lungs (alveolar
pressure) needs to
pressure) needs to
decrease so the air
decrease so the air
will rush into the
will rush into the
lungs, stretching the
lungs, stretching the
lungs. This happens
lungs. This happens
when the volume
when the volume
increases.
B. Process of Expiration
B. Process of Expiration
(breathing out)
(breathing out)
1.
1. Volume of thoracic cavity decreases.Volume of thoracic cavity decreases. a. Lungs recoils as the air exits.
a. Lungs recoils as the air exits.
b. The diaphragm and inspiration
b. The diaphragm and inspiration
muscles relax.
muscles relax.
2. Pressure increases – the air exits the
2. Pressure increases – the air exits the
lungs.
II. External Respiration
II. External Respiration
The movement of The movement of
oxygen and carbon
oxygen and carbon
dioxide between the
dioxide between the
alveoli of the lungs and
alveoli of the lungs and
the pulmonary
the pulmonary
capillaries across the
capillaries across the
alveoli-capillary
alveoli-capillary
membrane
A.
A. CarbaminohemoglobinCarbaminohemoglobin breaks down breaks down into carbon dioxide and hemoglobin.
into carbon dioxide and hemoglobin.
B.
B. Carbon dioxide moves out of the lung Carbon dioxide moves out of the lung capillary blood and into the alveolar air
capillary blood and into the alveolar air
and out of the body when expired air
and out of the body when expired air
leaves.
leaves.
C.
C. Oxygen moves into lung capillary blood.Oxygen moves into lung capillary blood. D.
D. Oxygen combines with hemoglobin and Oxygen combines with hemoglobin and forms
forms oxyhemoglobin.oxyhemoglobin.
III. Internal Respiration
III. Internal Respiration
The movement The movement
of oxygen and
of oxygen and
carbon dioxide
carbon dioxide
between the
between the
tissue
tissue
capillaries and
capillaries and
the tissue cells.
Internal Respiration
Internal Respiration
A.
A. Oxyhemoglobin breaks down and forms Oxyhemoglobin breaks down and forms oxygen and hemoglobin.
oxygen and hemoglobin.
B.
B. Oxygen goes from the capillary blood Oxygen goes from the capillary blood
into tissue cells.
into tissue cells.
C.
C. Carbon dioxide goes from the tissue Carbon dioxide goes from the tissue cells to the capillary blood.
cells to the capillary blood.
D.
D. Carbon dioxide combines with Carbon dioxide combines with hemoglobin making
hemoglobin making
carbaminohemoglobin.
Oxygen and Carbon dioxide always flow Oxygen and Carbon dioxide always flow
from an area of high concentration to an
from an area of high concentration to an
area of low concentration (diffusion!)
Organ Anatomy & Function
Organ Anatomy & Function
I.
I. Overall functionOverall function
A. Bring in oxygen (inspiration) and
A. Bring in oxygen (inspiration) and
expel carbon dioxide (expiration) and
expel carbon dioxide (expiration) and
exchange these gases.
exchange these gases.
B. Produce sound.
B. Produce sound.
C. Filter air and eliminate waste.
II. Mucous Membrane
II. Mucous Membrane
(MM)
(MM)
A.
A. Lines the air Lines the air passageways
passageways
B.
B. Covered with Covered with mucous to trap
mucous to trap
foreign particles.
foreign particles.
C.
C. Contain cilia which Contain cilia which move the trapped
move the trapped
particle out of the
particle out of the
respiratory system.
III. Organs of Upper
III. Organs of Upper
Respiratory Tract
Respiratory Tract
A.
A. Nose – warms and moistens air; Nose – warms and moistens air; contains sense organs
contains sense organs
1.
1. External Nares – nostrilsExternal Nares – nostrils 2.
2. Nasal Cavity – hollow chamber behind the Nasal Cavity – hollow chamber behind the nose
nose
3.
3. Nasal Conchae – membrane folds to Nasal Conchae – membrane folds to increase surface area
increase surface area
4.
Nose
Nose
5. Nasal Hairs – filter air and trap particles
5. Nasal Hairs – filter air and trap particles
6. Paranasal Sinuses – hollow spaces lined with
6. Paranasal Sinuses – hollow spaces lined with
MM that aid in sound production.
B. Pharynx
B. Pharynx
Passageway for food liquid and Passageway for food liquid and air. Lined with MM.
air. Lined with MM.
1.
1. Position – intermediate to the Position – intermediate to the nasal/oral cavity and the
nasal/oral cavity and the
vertebrae
vertebrae
2.
2. Divisions Divisions
a. Nasopharynx – opens to
a. Nasopharynx – opens to
auditory tubes; receives air
auditory tubes; receives air
from nasal cavity.
from nasal cavity.
b. Oropharynx – common
b. Oropharynx – common
pathway for food, liquid, and
pathway for food, liquid, and
air; contains opening from the
air; contains opening from the
mouth.
mouth.
c. Laryngopharynx – connect
c. Laryngopharynx – connect
esophogus and larynx
IV. Organs of the Lower
IV. Organs of the Lower
Respiratory Tract
Respiratory Tract
A.
A. Larynx – passageway for air only; aides in Larynx – passageway for air only; aides in sound production
sound production
1. Rings of Cartilage 1. Rings of Cartilage a. Three single rings a. Three single rings
1. Thyroid cartilage - (Adam’s apple) 1. Thyroid cartilage - (Adam’s apple)
Covers the front of larynxCovers the front of larynx
2. Epiglottis – flat that covers larynx 2. Epiglottis – flat that covers larynx
Larynx, cont.
Larynx, cont.
b. Three paired rings
b. Three paired rings
1. Cricoid – 1
1. Cricoid – 1stst ring ring of trachea
of trachea
2. Arytenoid – rings
2. Arytenoid – rings
that help voice
that help voice
production
2. Vocal Cords
2. Vocal Cords
Ligaments in PharynxLigaments in Pharynx
1. True cords – produce sound
1. True cords – produce sound
2. False cords – blocks particles from entering
B. Trachea
B. Trachea
Passageway for air, connect larynx to the Passageway for air, connect larynx to the
bronchi lined with MM
bronchi lined with MM
1.
1. Tube made of C rings of cartilage, they are Tube made of C rings of cartilage, they are for support and to hold the trachea open.
for support and to hold the trachea open.
2.
2. Obstruction of tracheaObstruction of trachea a.
a. Can result in death within secondsCan result in death within seconds
b.
b. Tracheostomy – incision in the trachea Tracheostomy – incision in the trachea
below the obstruction to make an
below the obstruction to make an
emergency airway
C. Bronchi
C. Bronchi
Branches of the trachea (left and right), Branches of the trachea (left and right),
line with MM, composed of cartilage rings.
line with MM, composed of cartilage rings.
1.
1. Branches Branches
a. Primary
a. Primary
b. Secondary
b. Secondary
c. Tertiary
c. Tertiary
2. Bronchial Tree – many sets of bronchial
2. Bronchial Tree – many sets of bronchial
branches, looks like an upside down tree
D. Bronchioles
D. Bronchioles
E. Alveolar Ducts
E. Alveolar Ducts
Microscopic cavity Microscopic cavity
at the end of the
at the end of the
bronchioles.
bronchioles.
1.
1. Each duct ends in a Each duct ends in a sac with many
sac with many
alveoli
alveoli
*Alveoli – exchange
*Alveoli – exchange
point of oxygen and
point of oxygen and
carbon dioxide with
carbon dioxide with
the blood capillary.
F. Lungs
F. Lungs
Cone shaped organs responsible for Cone shaped organs responsible for
breathing
breathing
a.
a. Base – bottom of lungBase – bottom of lung
b.
b. Apex – narrow top portionApex – narrow top portion c.
c. Hilus – where bronchus enters lungHilus – where bronchus enters lung d.
Lungs
Lungs
a.
a. Lobes – each lung is divided into lobesLobes – each lung is divided into lobes a. Right Lung has 3 lobes
a. Right Lung has 3 lobes
1. Superior
1. Superior
2. Middle
2. Middle
3. inferior
3. inferior
b. Left lung has 2 lobes
b. Left lung has 2 lobes
1. Superiof
Pulmonary Volumes and
Pulmonary Volumes and
Capacities
Capacities
Pulmonary Volumes
Pulmonary Volumes (normal rate: 12-18 (normal rate: 12-18 breaths/minute)
breaths/minute)
1.Tidal Volume (TV) – amount normally
1.Tidal Volume (TV) – amount normally
breathed in or out with each breath
breathed in or out with each breath
2. Inspiratory Reserve Volume
2. Inspiratory Reserve Volume (IRV) – (IRV) – amount of air that can be forcibly inhaled
amount of air that can be forcibly inhaled
after a normal inspiration
Pulmonary Volumes,
Pulmonary Volumes,
Cont.
Cont.
3. Expiratory Reserve Volume (ERV) –
3. Expiratory Reserve Volume (ERV) –
amount of air that can be forcibly
amount of air that can be forcibly
exhaled after expiring tidal volume
exhaled after expiring tidal volume
4. Residual Volume (RV) – amount of air
4. Residual Volume (RV) – amount of air
left in lungs after forceful exhalation.
Pulmonary Capacities
Pulmonary Capacities
1.
1. Inspiratory Capacity (IC) – max. amount Inspiratory Capacity (IC) – max. amount of air that can be inhaled after normal
of air that can be inhaled after normal
expiration. IC = TV + IRV
expiration. IC = TV + IRV
2.
2. Functional Residual Capacity (FRC) – Functional Residual Capacity (FRC) – amount of air left in lungs after normal
amount of air left in lungs after normal
tidal expiration. FRC = ERV + RV
Pulmonary Capacities
Pulmonary Capacities
Cont.
Cont.
3. Vital Capacity (VC) – max amount of air
3. Vital Capacity (VC) – max amount of air
that can forcefully be expired after max
that can forcefully be expired after max
inspiration. VC = TV + IRV + ERV
inspiration. VC = TV + IRV + ERV
4. Total Lung Capacity (TLC) – max
4. Total Lung Capacity (TLC) – max
amount of air in lungs following max
amount of air in lungs following max
inspiration
Controls of Respiration
Controls of Respiration
and Homeostasis
and Homeostasis
I.
I. Respiratory CenterRespiratory Center
A. The respiratory center is a group of
A. The respiratory center is a group of
neurons located in the medulla
neurons located in the medulla
oblongata and the pons of the brain
oblongata and the pons of the brain
stem.
B. The neuron groups work together differently to
B. The neuron groups work together differently to
send impulses to the respiratory muscles that
send impulses to the respiratory muscles that
control the size of the thoracic cavity which
control the size of the thoracic cavity which
controls breathing.
controls breathing.
1. Medullary rhythmicity area controls the normal
1. Medullary rhythmicity area controls the normal
rhythm of breathing.
rhythm of breathing.
a. The
a. The Inspiratory areaInspiratory area controls the controls the
impulses sent via the nerves to the inspiratory
impulses sent via the nerves to the inspiratory
muscles (diaphragm and intercostals).
muscles (diaphragm and intercostals).
b. The
b. The Expiratory area Expiratory area sends impulses via sends impulses via nerves to expiratory muscles for force expiration.
nerves to expiratory muscles for force expiration.
During normal breathing this area is inactive.
2.
2. Pneumotaxic Area - Pneumotaxic Area -
located in the upper pons,
located in the upper pons,
it brings on expiration by
it brings on expiration by
inhibiting or limiting
inhibiting or limiting
inspiration.
inspiration.
3.
3. Apneustic Area Apneustic Area – located – located in lower pons, prolongs
in lower pons, prolongs
inspiration by inhibiting
inspiration by inhibiting
expiration. The
expiration. The
pneumotaxic area can
pneumotaxic area can
override this response.
II. Regulator of Breathing
II. Regulator of Breathing
A.
A. The direct connection to the cerebral The direct connection to the cerebral cortex allows the voluntary regulation
cortex allows the voluntary regulation
breathing patterns.
breathing patterns.
B.
B. Stretch receptors on the lungs send Stretch receptors on the lungs send signal to Respiratory Center to inhibit
signal to Respiratory Center to inhibit
inspiration so lungs don’t overstretch.
inspiration so lungs don’t overstretch.
This is called the
C. Chemoreceptors sense changes in the
C. Chemoreceptors sense changes in the
CO
CO22 and H and H++ levels. If they increase too levels. If they increase too
much (hypercapnia), these receptors send
much (hypercapnia), these receptors send
signals to the chemosensitive area in the
signals to the chemosensitive area in the
medulla oblongata to increase breathing
medulla oblongata to increase breathing
rate.
rate.
D. Temperature is directly related to the rate
D. Temperature is directly related to the rate
of respiration. As the temp. decreases, so
of respiration. As the temp. decreases, so
does the respiration rate. A sudden drop in
does the respiration rate. A sudden drop in
temperature can cause
temperature can cause apneaapnea, a , a temporary stop in breathing.
E. Prolonged pain can also increase the
E. Prolonged pain can also increase the
respiration rate.
respiration rate.
http://www.youtube.com/watch?
http://www.youtube.com/watch?
v=RmMcqnXqrvA&safety_mode=true&persist_
v=RmMcqnXqrvA&safety_mode=true&persist_
safety_mode=1