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Assessing telomeric DNA content in pediatric cancers using whole genome sequencing data

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Figure

Figure 1 Association with matched non-tumor telomeric DNA content and age. (a) Comparison of age distribution of pediatric PCGPsamples and adult TCGA samples
Figure 2 Telomere analysis using whole-genome sequencing data of 235 pediatric cancersother two groups (Mann-Whitneyclustering, which divided theblue
Figure 3 Age distribution versus telomere statusno change. There is no significant difference in age distribution across the three groups (ANNOVA,
Figure 4 Validation of WGS telomeric DNA content predictions. (a) Quantitative PCR for a subset of samples, including 16 medulloblastomaand 11 neuroblastoma samples, showing changes in telomeric DNA content between normal and diagnosis log2(Absolute telome
+2

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