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HIV-1: tackling the obstacles that limit the effectiveness of CRISPR-Cas9 gene editing of the T cell co-receptor CCR5 Tatiana Hillman 1https://orcid.org/0000-0002-7539-0512

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Academic year: 2020

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Figure

Figure 1 The Life Cycle of HIV  The HIV-1 virus binds to the CD4 receptor of a T cell
Figure 2 The Absence of CCR5 and the Inhibition of HIV Attachment A mutation of CCR5 causes the receptor to malfunction and become inactive
Figure 3 CRISPR Cas9-sgRNA Excision of CCR5 The Cas9 nuclease uses sgRNA as a guide to target the specific CCR5 DNA sequence

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