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Cuboidal tethered cyclodextrin frameworks tailored for hemostasis and injured vessel targeting

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Academic year: 2020

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Figure

Figure 1. Design and characterization of CL-MOF, GS5-MOF and GS5-NS nanoparticles. GS5-MOF nanoparticles are cuboidal carriers with uniform sizes (200 nm), good cytocompatibility and stability
Figure 2. In vitro binding of CL-MOF, GS5-NS and GS5-MOF nanoparticles to activated platelet-coated surfaces versus platelet-deficient surfaces under flow conditions
Figure 3. In vitro activated platelet aggregation under static conditions. Enhanced activated platelet aggregation and higher colocalization were found with a cuboidal (green) with Cy5-labeled CL-MOF, GS5-NS and GS5-MOF nanoparticles
Figure 4. Analysis of in vitro clot formation in the presence of CL-MOF, GS5-NS and GS5-MOF nanoparticles
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