• No results found

The in vitro and vivo anti-tumor effects and molecular mechanisms of suberoylanilide hydroxamic acid (SAHA) and MG132 on the aggressive phenotypes of gastric cancer cells

N/A
N/A
Protected

Academic year: 2020

Share "The in vitro and vivo anti-tumor effects and molecular mechanisms of suberoylanilide hydroxamic acid (SAHA) and MG132 on the aggressive phenotypes of gastric cancer cells"

Copied!
18
0
0

Loading.... (view fulltext now)

Full text

Figure

Figure 1: The effects of SAHA and MG132 on the proliferation of gastric cancer cells. CCK-8 cell proliferation assays showed that SAHA and MG132 treatments induced cell death of MGC-803 and MKN28 cells in both concentration- and time-dependent manners with
Figure 2: The effects of SAHA on apoptosis, senescence and glucose catabolism of gastric cancer cells
Figure 3: The effects of SAHA on migration and invasion of gastric cancer cells. SAHA treatment increased the ability of MGC-803 and MKN28 cells to migrate and invade, especially at a low concentration (μM) by wound healing and transwell chamber A-C
Figure 3 (Continuedlamellipodia formation was observed using F-actin immunofluorescence staining after the treatment of both drugs  ): MG132 exposure had an inhibitory effect on the migration and invasion of both cancer cells (A-C)
+7

References

Related documents

Knowledge about sexual health is an important indicator in the development of healthy adolescent sexuality, but knowledge does not necessarily translate into behaviour.. Rather, it

Big Sib students’ perceptions of the educational environment at the school of medical sciences, Universiti Sains Malaysia, using Dundee ready educational environment measure

The extracted oil was immediately analyzed for chemical properties, such as iodine, acid and saponofication value, ester value and unsaponifiable matter while specific

We found that expression of SGLT1 and SMIT1 is signi fi - canctly higher than other SGLTs, indicating that other SGLT2- 6 may not play a main role in the glucose uptake of

Such workloads appear, for example, during the boot process of an operating system, where it checks the integrity of its components (see [‎15] for example). This

The primary end point of the study was the change from baseline in goblet cell density (determined by CIC) over the 3-month treatment period. Exploratory end

Fig- ures 6 and 7 show interpretations of the 0-lepton (2–6jets) and the 1-lepton analyses on the same 2 dimensional mass plane in one-step decay signals of squark and

Thrombosed arteriovenous (AV) fistulas with large venous aneurysms have poor treatment results, with both endovascular and surgical techniques, leading to a high rate of definitive